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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MeO-DiPT Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 27 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Foxy, Foxy methoxy, foxy-methoxy, 5meodipt

    Summary dose.wiki Erowid TripSit PsychonautWiki

    5-Methoxy-N,N-diisopropyltryptamine (also known as 5-MeO-DiPT, Foxy, and Foxy Methoxy) is a novel psychedelic substance of the tryptamine class that produces psychedelic effects when administered. It is related in structure to DiPT and 5-MeO-MiPT. The first human trials of 5-MeO-DiPT were undertaken by Alexander Shulgin in 1975. who would co-author and publish a paper detailing its synthesis and human psychopharmacology in 1981.

    Perspectives

    “Effects were present in twenty minutes, and I took my portable radio into the garden at forty minutes just to pull weeds. Each weed had special significance, and my cat Ms. joined me and agreed with me. This is excessively strange. The radio was discussing a President Ford fund-raiser, and continued with word sequences such as fund, fun, profun, profound, profane, refrain, and on and on. A car drove by with sitar music playing on its radio! Why not. And by my hour number three, I am back where I started. That was quite a morning.”

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 3-10mg 10-15mg 15-20mg 20mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-40 min 30-60 min 1-2 hrs 2-4 hrs 2-6 hrs 6-12 hrs
    Insufflated 4-19 min 15-30 min 45-90 min 1-3 hrs 2-4 hrs 4-8 hrs
    Smoked 1-4 min 4-10 min 30-90 min 1-2 hrs 2-6 hrs 4-8 hrs

    Effect Profile

    217 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 158 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.0
    Intense 8/10

    Strong visuals, auditory effects, and headspace with strong body load

    Visual Intensity ×3
    10
    color enhancement tracers drifting pattern recognition enhancement color shifting depth perception distortions +3 more
    Headspace Depth ×3
    8
    conceptual thinking personal bias suppression time distortion confusion
    Auditory Effects ×1
    10
    auditory distortions auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction bodily pressures muscle tension increased heart rate
    Empathogen 7.9
    Intense 8/10

    Strong euphoria, stimulation, and sensory enhancement with mild empathy

    Empathy / Social Openness ×3
    5
    empathy
    Euphoria / Mood Elevation ×2
    10
    cognitive euphoria euphoria emotional enhancement
    Stimulation ×1
    10
    stimulation restlessness increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement enhanced tactile sensation color enhancement visual acuity enhancement increased libido
    Stimulant 5.1
    Moderate+ 5/10

    Strong euphoria with strong anxiety/jitters, moderate stimulation, low focus

    Stimulation / Energy ×3
    7
    stimulation
    Euphoria / Mood Lift ×2
    9
    cognitive euphoria euphoria
    Focus / Productivity ×2
    1
    ⚠ Anxiety / Jitters ×1
    10
    restlessness increased heart rate vasoconstriction muscle tension

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    Phenethylamines

    Effects Erowid Bluelight

    Aggregated from 158 single-substance Erowid and 59 Bluelight experience reports (the Bluelight figures come from the 50 of them read for effects); 109 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 70

    52.9% (95% interval 46 to 60 percent) 77%
    48.1% (95% interval 41 to 55 percent) 85%
    42.3% (95% interval 36 to 49 percent) 82%
    38.0% (95% interval 32 to 45 percent) 85%
    37.0% (95% interval 31 to 44 percent) 86%
    28.0% (95% interval 18 to 42 percent) 86%
    26.5% (95% interval 21 to 33 percent) 86%
    24.0% (95% interval 14 to 37 percent) 84%
    24.0% (95% interval 14 to 37 percent) 86%
    21.1% (95% interval 16 to 27 percent) 86%
    20.0% (95% interval 11 to 33 percent) 82%
    20.0% (95% interval 11 to 33 percent) 84%
    17.8% (95% interval 13 to 24 percent) 78%
    16.0% (95% interval 8 to 28 percent) 84%
    16.0% (95% interval 8 to 28 percent) 84%
    15.9% (95% interval 12 to 21 percent) 87%
    15.4% (95% interval 11 to 21 percent) 82%
    14.0% (95% interval 7 to 26 percent) 86%
    14.0% (95% interval 7 to 26 percent) 76%
    14.0% (95% interval 7 to 26 percent) 83%
    Show 50 more positive effects
    12.0% (95% interval 6 to 24 percent) 82%
    12.0% (95% interval 6 to 24 percent) 82%
    10.6% (95% interval 7 to 16 percent) 85%
    10.1% (95% interval 7 to 15 percent) 80%
    10.0% (95% interval 4 to 21 percent) 85%
    8.0% (95% interval 3 to 19 percent) 85%
    8.0% (95% interval 3 to 19 percent) 88%
    8.0% (95% interval 3 to 19 percent) 85%
    8.0% (95% interval 3 to 19 percent) 82%
    7.7% (95% interval 5 to 12 percent) 80%
    7.2% (95% interval 4 to 12 percent) 82%
    6.0% (95% interval 2 to 16 percent) 83%
    6.0% (95% interval 2 to 16 percent) 87%
    6.0% (95% interval 2 to 16 percent) 78%
    6.0% (95% interval 2 to 16 percent) 80%
    6.0% (95% interval 2 to 16 percent) 80%
    6.0% (95% interval 2 to 16 percent) 82%
    6.0% (95% interval 2 to 16 percent) 82%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 72%
    4.0% (95% interval 1 to 14 percent) 85%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 80%
    4.0% (95% interval 1 to 14 percent) 88%
    2.5% (95% interval 1 to 6 percent) –
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 82%
    2.0% (95% interval 0 to 10 percent) 87%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 90%
    Visual Effects 2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%

    Adverse Effects 60

    50.0% (95% interval 37 to 63 percent) 86%
    39.4% (95% interval 33 to 46 percent) 84%
    32.0% (95% interval 21 to 46 percent) 82%
    31.7% (95% interval 26 to 38 percent) 81%
    23.5% (95% interval 18 to 30 percent) 88%
    22.1% (95% interval 17 to 28 percent) 84%
    18.0% (95% interval 10 to 31 percent) 77%
    16.0% (95% interval 8 to 28 percent) 81%
    16.0% (95% interval 8 to 28 percent) 86%
    16.0% (95% interval 8 to 28 percent) 77%
    14.0% (95% interval 7 to 26 percent) 79%
    14.0% (95% interval 7 to 26 percent) 82%
    14.0% (95% interval 7 to 26 percent) 80%
    10.0% (95% interval 4 to 21 percent) 82%
    10.0% (95% interval 4 to 21 percent) 76%
    10.0% (95% interval 4 to 21 percent) 81%
    10.0% (95% interval 4 to 21 percent) 82%
    10.0% (95% interval 4 to 21 percent) 84%
    9.2% (95% interval 6 to 14 percent) 81%
    8.7% (95% interval 6 to 13 percent) 76%
    5.1% (95% interval 3 to 10 percent) –
    2.5% (95% interval 1 to 6 percent) –
    Show 38 more adverse effects
    8.0% (95% interval 3 to 19 percent) 79%
    6.8% (95% interval 4 to 11 percent) 79%
    6.7% (95% interval 4 to 11 percent) 85%
    6.7% (95% interval 4 to 11 percent) 90%
    6.0% (95% interval 2 to 16 percent) 77%
    6.0% (95% interval 2 to 16 percent) 73%
    6.0% (95% interval 2 to 16 percent) 82%
    6.0% (95% interval 2 to 16 percent) 87%
    6.0% (95% interval 2 to 16 percent) 78%
    6.0% (95% interval 2 to 16 percent) 80%
    6.0% (95% interval 2 to 16 percent) 81%
    4.4% (95% interval 2 to 9 percent) –
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 75%
    4.0% (95% interval 1 to 14 percent) 78%
    4.0% (95% interval 1 to 14 percent) 82%
    4.0% (95% interval 1 to 14 percent) 79%
    4.0% (95% interval 1 to 14 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 75%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 65%
    2.0% (95% interval 0 to 10 percent) 80%
    2.0% (95% interval 0 to 10 percent) 90%
    2.0% (95% interval 0 to 10 percent) 70%
    2.0% (95% interval 0 to 10 percent) 85%
    2.0% (95% interval 0 to 10 percent) 80%

    Also reported in combinations. In the 109 5-MeO-DiPT reports where another drug was taken too, 14 (12.8%) mention hospital, emergency services or an overdose, 3 (2.8%) a seizure and 5 (4.6%) psychosis. In the 158 single-substance reports: 10.1%, 2.5% and 5.1%. These are not in the figures above: they cannot be put down to 5-MeO-DiPT alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check 5-MeO-DiPT with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 3 positive 2 neutral 3 cautionary visit
    Very Pleasant, but Extremely Intense positive exp #15177

    Preparation: I read the Tihkal report and several other reports online before trying this drug. I highly recommend doing the same, not just with this drug, but any. The most useful information for this experience was to go in with an empty stomach. The body load with this chemical is unbelieveably high.

    DJM · 12.5 mg oral / 9.4 mg oral
    A Universe I Call the 'FOX' positive exp #3384

    Received 5-MeO-DIPT in mail two days prior, mixed 250 mg. in with 250 ml. of purified water. Empty stomach except for a small salad and a nutrigrain bar at lunch. Open and clear mind. I'm in a good mood. 8:15 PM. Me and good friend J dose 10 ml. each mixed in with fruit juice.

    Q-tip · 10 mg oral
    A Vulpine Adventure cautionary exp #28543

    This was my first experience with ย‘foxy methoxyย’ and certainly will not be my last. My friend Giles had acquired large quantities of pure 5-MeO-DIPT from an online source. Before taking a new drug I would normally research it carefully, working out dosage, the expected effects, duration etc.

    Smoke & Mirrors · 22.5 mg oral
    Challenging Foxy Orthodoxy neutral exp #115045

    The following Greek letters have been changed to protect the innocent. This trip report is written by Theta. This was our second experience with 5-MeO-DiPT, and our first time smoking it.

    Kaleida · 5 mg smoked / repeated smoked
    A World of Difference positive exp #21989

    BODY WEIGHT: 143bs Note: If you do this chemical and come down... good luck sleeping! I'm still up! and have I got a crazy story to tell... On a bright beautiful saturday afternoon in my college dormroom, I recieved a call (that I was awaiting) from a few friends of mine.

    The Hunted Cat
    Stoned, Ripped, Twisted... Good People neutral exp #15782

    After getting our Jollies by scaring the shit out of a church-going brother and a sister by chasing them around a parking in my mothers car void any headlights, My friends 'Green', 'Brown' and myself returned to our prearranged parking spot and continued waiting for our irresponsible Foxy dealer.

    Murdock
    Psychotic Episode & Temporary Organ Failure cautionary exp #27587

    I recently spent four days in the hospital because of a disastrous 5-meo-dipt trip that included a psychotic episode, temporary failure of my kidneys, and suspicion of heart problems.

    I Am LeBron · 25 mg oral
    Human Conscience and Chemical Intercourse cautionary exp #22261

    It had been a long time since I had touched a hallucinogenic substance. There was a reason I had quit doing them. As I lay in bed almost two years ago, unable to sleep after a horrible experience on a heavy dose of AMT, I knew that something had to change.

    Raoul · 35 mg oral

    Bluelight Reference Guide Bluelight

    Tryptamines The Big & Dandy 5-MeO-DiPT Thread

    Comparisons 5-MeO-MiPT vs 5-MeO-DiPT Combinations 5-MeO-DIPT & MDMA Original Post: Well I've taken 5-MeO-DiPT all ways but snorting now(and of course I've not plugged it thats just gross).....I've come to the conclusion that IV is the best route for 5-MeO-Dipt.

    Read full thread on Bluelight โ†’

    PiHKAL / TiHKAL Shulgin

    TiHKAL #37: 5-MeO-DIPT

    “Effects were present in twenty minutes, and I took my portable radio into the garden at forty minutes just to pull weeds. Each weed had special significance, and my cat Ms. joined me and agreed with me. This is excessively strange. The radio was discussing a President Ford fund-raiser, and continued with word sequences such as fund, fun, profun, profound, profane, refrain, and on and on. A car drove by with sitar music playing on its radio! Why not. And by my hour number three, I am back where I started. That was quite a morning.”

    โ€” Alexander Shulgin, TiHKAL (with 6 mg, orally)
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 5-MeO-DiPT, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "5-MeO-DiPT (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference)
    5-MeO-DiPT: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    
    Insufflated duration: onset 4-19m ยท come-up 15-30m ยท peak 0.75-1.5h ยท offset 1-3h ยท total 4-8h ยท after-effects 2-4h
    Smoked duration: onset 1-4m ยท come-up 4-10m ยท peak 0.5-1.5h ยท offset 1-2h ยท total 4-8h ยท after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.