This was It, the culmination of all my questions and all my fears every state of mind that I knew to be real or simply thought was imaginary was loaded into a cannon and shot directly into my feeble perception of reality, call it god, enlightenment, it may simply be known as I AM I orally ingested one 14mg capsule of 2...
2C-E
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 28 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 28 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Aliases: Europa, Eternity, Aquarust, 2ce
Summary
2,5-Dimethoxy-4-ethylphenethylamine (also known as 2C-E, or colloquially as "Aquarust" and "Eternity") is a lesser-known psychedelic substance of the phenethylamine class. It is a member of the 2C-x family of psychedelic phenethylamines, which are closely related to the classical psychedelic mescaline. Like other psychedelics, it is thought to produce its effects by binding to serotonin receptors in the brain, although the precise mechanism is poorly understood.
Perspectives
“It seems I have the misfortune of adverse reactions to 2C-E, what has been tauted as a spectacular substance by many. The headspace was unique and enjoyable, as was the visual aspect, I feel like thereβs a lot of directions to take this substance, but unforuntaely my explorations seem to be hampered by the feeling of being acutely poisoned.”
“There was a strange devil-angel pairing. As I was being told of the ecstatic white-light ascent of my partner into the God-space of an out-of-body experience, I was fighting my way out of a brown ooze. She saw the young Jesus at the bottom of a ladder drifting upwards step by step to some taking-off place, and I saw all the funny gargoyles around the base of the ladder surrounded by picnic bunting. For me it was the 4th of July, rather than Easter!”
“This wasn't bouncy or fun but there was a depth there waiting to be explored. I felt as though I was at the door, peeping inside.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-15mg | 15-30mg | 30mg+ |
| Insufflated | 1-4mg | 4-7mg | 7-14mg | 14mg+ |
Light
Common
Strong
Heavy
Sources
Oral
Dose ladder — PsychonautWikiInsufflated
Dose ladder — PsychonautWikiOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-90 min | 30-90 min | 2-4 hrs | 2-3 hrs | 4-9 hrs |
| Insufflated | 1-10 min | - | 1.5-3 hrs | 1-2 hrs | 6-14 hrs |
Effect Profile
362 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 235 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
8.8
Intense+
9/10
Strong visuals, headspace, and auditory effects with strong body load
Visual Intensity
×3
10
internal hallucinations
colour enhancement
autonomous entities
drifting
tracers
synaesthesia
+8 more
Headspace Depth
×3
10
conceptual thinking
thought connectivity
emotion enhancement
perspective alterations
perspective distortions
personal bias suppression
+2 more
Auditory Effects
×1
10
auditory distortion
auditory enhancement
auditory hallucinations
auditory hallucination
synaesthesia
Body Load / Somatic Effects
×1
10
nausea
temperature regulation suppression
muscle tension
teeth grinding
increased heart rate
Tolerance
Build-up
develops rapidly after a single use
Reset
7β14 days for baseline
Tolerance Decay
Full tolerance
1d
Half tolerance
7d
Baseline
~14d
Tolerance patterns for 5βHT2A psychedelics are based on community reports and general HR guidance; high interβindividual variability. Allow 1β2 weeks between sessions for best effect restoration.
Cross-Tolerances
Effects
Aggregated from 235 single-substance Erowid and 127 Bluelight experience reports (the Bluelight figures come from the 50 of them read for effects); 161 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Effect glossary — · full glossary
Positive Effects 74
70.2% (95% interval 65 to 75 percent)
79%
54.7% (95% interval 49 to 60 percent)
87%
41.8% (95% interval 36 to 48 percent)
82%
40.0% (95% interval 34 to 46 percent)
86%
32.6% (95% interval 28 to 38 percent)
87%
31.5% (95% interval 26 to 37 percent)
79%
29.5% (95% interval 24 to 35 percent)
87%
28.0% (95% interval 18 to 42 percent)
85%
27.0% (95% interval 22 to 32 percent)
84%
Auditory Effects
24.9% (95% interval 20 to 30 percent)
82%
24.2% (95% interval 20 to 30 percent)
87%
24.0% (95% interval 14 to 37 percent)
86%
24.0% (95% interval 14 to 37 percent)
84%
20.0% (95% interval 11 to 33 percent)
81%
20.0% (95% interval 11 to 33 percent)
88%
20.0% (95% interval 11 to 33 percent)
84%
18.0% (95% interval 10 to 31 percent)
84%
18.0% (95% interval 10 to 31 percent)
83%
16.5% (95% interval 13 to 21 percent)
86%
16.0% (95% interval 8 to 28 percent)
82%
Show 54 more positive effects
16.0% (95% interval 8 to 28 percent)
83%
15.1% (95% interval 11 to 20 percent)
84%
14.0% (95% interval 7 to 26 percent)
81%
12.0% (95% interval 6 to 24 percent)
80%
12.0% (95% interval 6 to 24 percent)
87%
11.9% (95% interval 9 to 16 percent)
75%
11.2% (95% interval 8 to 15 percent)
80%
10.0% (95% interval 4 to 21 percent)
83%
10.0% (95% interval 4 to 21 percent)
82%
10.0% (95% interval 4 to 21 percent)
81%
10.0% (95% interval 4 to 21 percent)
75%
10.0% (95% interval 4 to 21 percent)
88%
10.0% (95% interval 4 to 21 percent)
80%
8.0% (95% interval 3 to 19 percent)
76%
8.0% (95% interval 3 to 19 percent)
84%
8.0% (95% interval 3 to 19 percent)
80%
8.0% (95% interval 3 to 19 percent)
82%
6.7% (95% interval 4 to 10 percent)
78%
6.0% (95% interval 2 to 16 percent)
83%
6.0% (95% interval 2 to 16 percent)
80%
6.0% (95% interval 2 to 16 percent)
80%
6.0% (95% interval 2 to 16 percent)
85%
6.0% (95% interval 2 to 16 percent)
83%
6.0% (95% interval 2 to 16 percent)
85%
6.0% (95% interval 2 to 16 percent)
78%
4.0% (95% interval 1 to 14 percent)
85%
4.0% (95% interval 1 to 14 percent)
72%
4.0% (95% interval 1 to 14 percent)
80%
4.0% (95% interval 1 to 14 percent)
90%
4.0% (95% interval 1 to 14 percent)
75%
4.0% (95% interval 1 to 14 percent)
82%
4.0% (95% interval 1 to 14 percent)
85%
4.0% (95% interval 1 to 14 percent)
78%
2.0% (95% interval 0 to 10 percent)
85%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
70%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
85%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
90%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
80%
Adverse Effects 40
52.6% (95% interval 47 to 58 percent)
82%
45.3% (95% interval 40 to 51 percent)
85%
32.0% (95% interval 21 to 46 percent)
81%
28.1% (95% interval 23 to 34 percent)
85%
22.4% (95% interval 18 to 28 percent)
79%
20.7% (95% interval 16 to 26 percent)
78%
18.0% (95% interval 10 to 31 percent)
83%
12.0% (95% interval 6 to 24 percent)
78%
10.0% (95% interval 4 to 21 percent)
93%
9.8% (95% interval 7 to 14 percent)
72%
8.4% (95% interval 6 to 12 percent)
85%
8.1% (95% interval 5 to 12 percent)
–
8.0% (95% interval 3 to 19 percent)
81%
8.0% (95% interval 3 to 19 percent)
84%
7.7% (95% interval 5 to 11 percent)
82%
6.0% (95% interval 2 to 16 percent)
82%
6.0% (95% interval 2 to 16 percent)
75%
6.0% (95% interval 2 to 16 percent)
78%
4.7% (95% interval 3 to 8 percent)
–
4.0% (95% interval 1 to 14 percent)
82%
3.8% (95% interval 2 to 7 percent)
–
Show 19 more adverse effects
4.0% (95% interval 1 to 14 percent)
78%
4.0% (95% interval 1 to 14 percent)
80%
4.0% (95% interval 1 to 14 percent)
80%
2.8% (95% interval 1 to 5 percent)
90%
Gastrointestinal Effects
2.0% (95% interval 0 to 10 percent)
85%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
70%
2.0% (95% interval 0 to 10 percent)
85%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
70%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
75%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
80%
2.0% (95% interval 0 to 10 percent)
85%
Also reported in combinations. In the 161 2C-E reports where another drug was taken too, 9 (5.6%) mention hospital, emergency services or an overdose, 1 (0.6%) a seizure and 3 (1.9%) psychosis. In the 235 single-substance reports: 11.5%, 3.8% and 4.7%. These are not in the figures above: they cannot be put down to 2C-E alone, and a mention is not always something that happened to the writer.
Combinations
Cross-Check 2C-E with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 3 positive 2 neutral 3 cautionary visit
**Preface:** 2,5-Dimethoxy-4-ethylphenethylamine (2C-E) barely needs an introduction, itΒs one of Alexander ShulginΒs "magical half-dozen" members and rightfully so. This substance is an unpredictable, dose-sensitive and long-lasting phenethylamine which is quite unlike the other 2C compounds.
Setting: Remote forest location. Set: Good mood, excited, longing for peace. Within an hour the most difficult feelings imaginable came up and I soon realized there was no way to escape them.
**I realize that making the decision of taking an unknown chemical of an unknown dosage was not the wisest. I was fifteen and made a very uneducated dangerous decision the night I took 2C-E** This is the story of my first earth shattering, psychedelic trip experience.
A brief backround of me: Served 4 years in the Marine Corps, including a tour in Iraq. Developed a drug problem after returning from Iraq, got an Other Than Honorable discharge. Which is actually pretty lucky, considering I was dealing. Faced 60 years for distribution of Ecstasy, LSD, Mushrooms, and Cocaine.
After Burning Man 2000, I magically found myself in possession of a little foil packet containing 100 mg of 2C-E. This was probably something I'd never see again, so I had to make the most of these precious crumbs.
Intro: This is my first experience with psychoactive substances. Before this night I had only smoked dro once. I have really close friends who helped sit me, and understood the effects of 2c-e and how to take care of me. Overall I couldn't tell you if it was a good or bad trip, but only it was perfect and complete.
11/24/12 ___________ 2C-E Report ___________ Dose: 36 mg 6 foot male 175 pounds __________________________________________________ __________________________________________________ ***************WARNING**************************** ************************************************** ******** Ingested 36MG at 4:58 A.M I...
Bluelight 8 threads 3 positive 3 neutral 2 cautionary visit
(2C-E / 8mg - rectally) - 3rd Time - Pleasant and Powerful Despite I considered taking 2C-E again with considerable trepidation, although all of my experiences so far have been positive. I have considered taking it several times in the last year, but I always decided not to.
I have long wanted to write a trip report on my 2c-E experience that I had about 6-7 years ago, as it continues to remain the most profound experience I have ever had on any psychedelic drug.
Preface: 2,5-Dimethoxy-4-ethylphenethylamine (2C-E) barely needs an introduction, itβs one of Alexander Shulginβs "magical half-dozen" members and rightfully so. This substance is an unpredictable, dose-sensitive and long-lasting phenethylamine which is quite unlike the other 2C compounds.
The other day I had a breathtaking experience with 2C-E that I'd like to share. As with my other recent reports, this will begin with my real-time and unedited notes I took during the experience, and will then summarize in a more coherent fashion, written the next day.
Hello bluelight, I wrote a long in details trip report for 2C-E. I want to send it to erowid.org but I would need some reviews before. It was translated from french and I am not sure about some expressions and spelling, etc. If someone could point this out to me, it would really be appreciate.
Substance: 2C-E HCl (2,5-dimethoxy-4-ethylphenethylamine hydrochloride) Dosage: 13.8 mg (directly on an analytical balance, not calibrated) Purity: homogenous on TLC, sharp melting point Age: mid-20s Weight: ~ 60 kg, a bit underweight Previous experiences: a couple of psychedelics (mostly phenethylamines), various enta...
2C-E - A trip back to childhood (Warning, very long) June 25th 7:40 P.M. β June 26th 10:00 A.M. β Duration of Experience: 14:20 approx., effects may have extended for the entire day to some degree. Dosage β Dosage was to some extent unknown. NOT RECOMMENDED. Unless you are like me, and crazy.
11/24/12 ___________ 2C-E Report ___________ Dose: 36 mg 6 foot male 175 pounds ___________________________________________________________________________________________________________ ***************WARNING************************************************************************************** Ingested 36MG at 4:58 A...
Dose.wiki 3 reports 1 positive 2 neutral visit
This trip was an absolutely mindblowing experience and easily the hardest I have tripped in over two years. It seems that somewhere in the mind, there is a button that triggers the brain into activating a "complete simulate render 3D hallucinate everythingβ¦
It seems I have the misfortune of adverse reactions to 2C-E, what has been tauted as a spectacular substance by many. The headspace was unique and enjoyable, as was the visual aspect, I feel like thereβs a lot of directions to take this substance, butβ¦
I swallow the 2C-E pill. Slight headspace, faint tingles that feel like theyβre moving outwardly from my core. Definitely feeling altered. Thoughts feel stimulated in a creative and conceptual way, overall mild stimulation Vision is slightly distorted, harderβ¦
Bluelight Reference Guide
The Big & Dandy 2C-E Thread (Second Edition)
Welcome to the Big & Dandy 2C-E Thread Previous Big & Dandy 2C-E Thread: {First page} {Last Page} Next Big & Dandy 2C-E Thread: {First page} External Information Links: Erowid 2C-E Vault (experience reports) PIHKAL Entry for 2C-E Wikipedia entry Focused Discussion Sub-Threads Please use these threads if you have questi...
Read full thread on Bluelight βPiHKAL / TiHKAL
PiHKAL #24: 2C-E
“There was a strange devil-angel pairing. As I was being told of the ecstatic white-light ascent of my partner into the God-space of an out-of-body experience, I was fighting my way out of a brown ooze. She saw the young Jesus at the bottom of a ladder drifting upwards step by step to some taking-off place, and I saw all the funny gargoyles around the base of the ladder surrounded by picnic bunting. For me it was the 4th of July, rather than Easter!”
2C-E's nerd page
Pharmacology, chemical data, effect profiles, and more
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