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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-APB Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Head candy, 5apb

    Summary dose.wiki Erowid TripSit PsychonautWiki

    5-(2-Aminopropyl)benzofuran (commonly known as 5-APB) is a lesser-known novel entactogen of the benzofuran class that produces MDA-like entactogenic and stimulating effects when administered. It is structurally related to entactogens like 5-MAPB, 6-APB, and MDA. 5-APB was first synthesized in 1993 by psychedelic chemist and researcher David E.

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 40-60mg 60-80mg 80-100mg 100mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 45-90 min 2-4 hrs 1.5-3 hrs 6-48 hrs 7-8 hrs
    Insufflated 4-15 min 19-40 min 2-4 hrs 1.5-3 hrs 4-24 hrs 7-8 hrs
    Rectal 10-30 min 45-90 min 2.5-4 hrs 2-3 hrs 6-24 hrs 7-8 hrs

    Effect Profile

    8 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 5.5
    Strong 6/10

    Strong visuals and auditory effects with strong body load, mild headspace

    Visual Intensity ×3
    8
    visual geometry color enhancement tracers pattern recognition enhancement
    Headspace Depth ×3
    4
    personal meaning enhancement emotion enhancement time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression vasoconstriction teeth grinding increased heart rate jaw clenching +1 more
    Empathogen 9.1
    Intense+ 9/10

    Strong empathy and euphoria with moderate stimulation and sensory enhancement

    Empathy / Social Openness ×3
    10
    empathy enhancement empathy empathy, affection and sociability enhancement feelings of empathy sociability enhancement affection enhancement +1 more
    Euphoria / Mood Elevation ×2
    10
    physical euphoria euphoria cognitive euphoria emotion enhancement
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 6.9
    Strong+ 7/10

    Strong euphoria and focus with strong anxiety/jitters, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement analysis enhancement memory enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding jaw clenching vasoconstriction +1 more

    Tolerance

    No tolerance chart. No study has measured how long tolerance to it lasts, so this page shows what is known instead of a curve.

    No study has measured tolerance to 5-APB in people; research so far is on cells, rats and poisoning cases. PsychonautWiki estimates that tolerance halves in 3-7 days and is gone in 1-2 weeks, without citing a source. Lab tests show 5-APB activates the 5-HT2B receptor, which is linked to heart-valve damage, so regular use carries a risk of its own.

    Sources: Iversen et al. 2013 ยท Rickli et al. 2015 ยท PsychonautWiki: 5-APB

    Cross-Tolerances

    Effects Erowid Bluelight

    Aggregated from 2 single-substance Erowid and 6 Bluelight experience reports; 8 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 2 single-substance Erowid and 6 Bluelight reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 16

    5 of 6 91%
    4 of 6 89%
    4 of 6 89%
    2 of 6 85%
    2 of 6 90%
    2 of 6 80%
    2 of 6 75%
    2 of 6 75%
    2 of 6 75%
    1 of 6 80%
    1 of 6 80%
    1 of 6 85%
    1 of 6 85%
    1 of 6 80%
    1 of 6 85%
    1 of 6 80%

    Adverse Effects 7

    2 of 6 82%
    2 of 6 82%
    1 of 6 70%
    1 of 6 75%
    1 of 6 75%
    1 of 6 80%
    1 of 6 65%

    Combinations TripSit

    Cross-Check 5-APB with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Bluelight 2 threads 2 positive visit
    5 Apb 80 Mg Pill Head Perspective Not What I Was Looking For positive

    This is my first report on bluelight so here goes! For a quick background on me to get where this report is coming from I have been an on off heavy user of mdma + cathonines for a few years.

    80 mg mentioned in the thread; auto-extracted, unverified
    5 Apb 110mg First Time Amazing Body High positive

    Forewarning: As with my 6-APB report, I'd like to add a word of caution to this. 5-APB is an MDA analogue, and as such it should be treated with the same caution as MDA - using it more than once a month (ideally you should use it less frequently than once a month too) is likely to lead to similar issues of serotonin re...

    110 mg mentioned in the thread; auto-extracted, unverified
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 5-APB, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "5-APB (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference)
    5-APB: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    
    Insufflated duration: onset 4-15m ยท come-up 19-40m ยท peak 2-4h ยท offset 1.5-3h ยท total 7-8h ยท after-effects 4-24h
    Rectal duration: onset 10-30m ยท come-up 0.75-1.5h ยท peak 2.5-4h ยท offset 2-3h ยท total 7-8h ยท after-effects 6-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.