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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-EPT Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: Eprocin

    Summary dose.wiki TripSit PsychonautWiki

    4-HO-EPT is a novel research chemical with very little history of human use before 2016 and almost no scientific research on its pharmacology, metabolism, or toxicity. Unlike more visual tryptamines, it primarily enhances colors with a neon quality rather than producing strong visual distortions. Users report a strong euphoric body high sometimes compared to opiates, with a generally light and positive mindset.

    Dose Information source varies by band

    ROA Light Common Strong Heavy
    Oral 15-20mg 30-40mg 40-60mg 60mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — Light–Strong: PsychonautWiki · Heavy: above the Strong band, added by this site; no source states this figure

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 30-40 min 1-2 hrs 1-2 hrs 2-4 hrs 4-8 hrs
    Smoked 1-4 min 4-10 min 15-30 min 30-60 min 1-2 hrs 4-8 hrs

    Effect Profile

    3 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.1
    Intense 8/10

    Strong visuals and auditory effects with moderate headspace, mild body load

    Visual Intensity ×3
    10
    color enhancement tracers drifting pattern recognition enhancement color shifting depth perception distortions +2 more
    Headspace Depth ×3
    7
    conceptual thinking emotion enhancement thought loops personal bias suppression time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    4
    nausea increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    Phenethylamines

    Effects Erowid

    Aggregated from 3 single-substance Erowid experience reports; 5 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 3 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 4

    3 of 3 –
    3 of 3 –
    3 of 3 –
    3 of 3 –

    Adverse Effects 0

    Combinations TripSit

    Cross-Check 4-HO-EPT with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 5 reports 1 positive 4 neutral visit
    Amazing Body High positive exp #116027

    Before this trip I had only used 2C-B and LSD. Last experience was with LSD 5 months before. I wanted to remind me psychedelic thoughts, have fun and explore something new for me.

    tvojemama
    Intense Energy, Calm Contemplation neutral exp #114998

    4-HO-EPT: Intense Energy, Calm Contemplation 11-27-2020 by Xorkoth 2:25pm (T+0:00) - I ingested 42mg orally at this point. It was a fine, chalky powder, like basically all of the 4-sub tryptamines are. Unlike the others, its taste is really surprising.

    Xorkoth · 42 mg oral / oral
    Reaching The Breaking Point neutral exp #109857

    This was my fourth experience with 4-HO-EPT. I have to say, as much as I was looking forward to this trip, it was kind of a mixed bag, and probably more on the negative side.

    Kaleida · 100 mg oral / smoked / repeated inhaled / repeated smoked
    Narcotic Psychedelia neutral exp #110915

    This was my sixth experience with 4-HO-EPT. The experience as whole actually wasn't really that remarkable, and normally I probably wouldn't write a report about such a trip on half the maximum dose I have already written about before, but I did want to get this one out there due to the different perspective I took on...

    Kaleida · 55 mg oral / smoked / repeated inhaled / smoked
    Uninspiring First Time neutral exp #112027

    The following is an experience report which details my first (as well as my partnerΒ’s first) experience taking 4-HO-EPT. Having tried other 4-substituted tryptamines including 4-HO-MPT, 4-HO-MiPT, and 4-AcO-MiPT, I was looking forward to adding this substance to my 4-sub repertoire.

    johnsonville
    Dose.wiki 1 report 1 neutral visit
    Tense and Restless 45mg oral, powder neutral

    Unfortunately, this turned out to be a disappointing substance. Maybe it would have been more enjoyable to do it while walking around or doing something, as I just felt very restless and tense the entire time. Aside from an elevated heartrate and the…

    by froggie

    Bluelight Reference Guide Bluelight

    β˜› Official ☚ The Big & Dandy 4-HO-EPT Thread

    Welcome to the Big & Dandy 4-HO-EPT Thread! 4-hydroxy-N-ethyl-N-propyltryptamine There is almost no information available about the chemical as of this post so there's not much else to put here, but it has recently become widely available and thus deserves its own thread.

    Read full thread on Bluelight β†’
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 4-HO-EPT, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "4-HO-EPT (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference)
    4-HO-EPT: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    
    Smoked duration: onset 1-4m Β· come-up 4-10m Β· peak 15-30m Β· offset 0.5-1h Β· total 4-8h Β· after-effects 1-2h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.