Prequel: I wanted to specifically enter this story, as it is the most recent enjoyable trip I have had with the nBomes and since that there is barely anything on 25B, which I have nicknamed her Beautrice-25 for her incredible beauty, the gemstone of all nBomes that are more of a true psychedelic than just a common good...
25B-NBOMe
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Aliases: 25b
Summary
25B-NBOMe (also known as Cimbi-36, NBOMe-2C-B and 2C-B-NBOMe) is novel psychedelic substance of the phenethylamine class. It is a member of the 25x-NBOMe series, a recently discovered group of potent psychedelic compounds derived from the 2C-x family. The name 25B-NBOMe, which is short-hand for 2C-B-NBOMe, indicates it is a derivative of the phenethylamine psychedelic 2C-B.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 50-200ยตg | 200-350ยตg | 350-500ยตg | 500ยตg+ |
| Sublingual | 100-300ยตg | 300-500ยตg | 500-700ยตg | 700ug+ |
Light
Common
Strong
Heavy
Sources
Insufflated
Dose ladder — Light: PsychonautWiki, TripSit · Common: dose.wiki, PsychonautWiki, TripSit · Strong: dose.wiki, PsychonautWiki · Heavy: dose.wikiSublingual
Dose ladder — Light: PsychonautWiki, TripSit · Common: dose.wiki, PsychonautWiki · Strong: dose.wiki, PsychonautWiki, TripSit · Heavy: dose.wiki, TripSitOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Insufflated | 1-4 min | - | 8-12 hrs | - | 8-12 hrs |
| Sublingual | 18-42 min | 30-90 min | 4-6 hrs | 2-4 hrs | 8-12 hrs |
Effect Profile
24 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
9.0
Intense+
9/10
Strong visuals, headspace, and auditory effects with strong body load
Visual Intensity
×3
10
internal hallucinations
autonomous entities
colour enhancement
drifting
tracers
colour shifting
+6 more
Headspace Depth
×3
10
conceptual thinking
thought connectivity
emotion enhancement
perspective alterations
personal bias suppression
confusion
+1 more
Auditory Effects
×1
10
auditory distortion
auditory enhancement
auditory hallucinations
auditory hallucination
Body Load / Somatic Effects
×1
8
nausea
vasoconstriction
muscle tension
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use; redosing is especially dangerous
Reset
7โ14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Effects
Aggregated from 17 single-substance Erowid and 7 Bluelight experience reports; 16 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Rows resting on fewer than 20 reports show a count (“3 of 7”) instead of a bar. Why 20?
Effect glossary — · full glossary
Positive Effects 30
75.0% (95% interval 55 to 88 percent)
82%
50.0% (95% interval 31 to 69 percent)
85%
41.7% (95% interval 24 to 61 percent)
80%
33.4% (95% interval 18 to 53 percent)
90%
33.4% (95% interval 18 to 53 percent)
75%
33.3% (95% interval 18 to 53 percent)
90%
25.0% (95% interval 12 to 45 percent)
80%
20.8% (95% interval 9 to 40 percent)
70%
3 of 7
77%
3 of 7
83%
5 of 17
–
2 of 7
85%
2 of 7
75%
2 of 7
85%
3 of 17
–
3 of 17
–
1 of 7
70%
1 of 7
85%
1 of 7
80%
1 of 7
80%
Show 10 more positive effects
1 of 7
80%
1 of 7
75%
1 of 7
75%
1 of 7
80%
1 of 7
75%
1 of 7
75%
1 of 7
85%
1 of 7
85%
1 of 7
75%
1 of 7
80%
Adverse Effects 26
54.2% (95% interval 35 to 72 percent)
88%
29.2% (95% interval 15 to 49 percent)
85%
25.0% (95% interval 12 to 45 percent)
75%
25.0% (95% interval 12 to 45 percent)
85%
2 of 7
85%
2 of 7
88%
2 of 7
88%
2 of 7
90%
2 of 7
78%
3 of 17
–
3 of 17
–
1 of 7
75%
1 of 7
80%
1 of 7
85%
1 of 7
75%
1 of 7
75%
1 of 7
80%
1 of 7
70%
1 of 7
80%
1 of 7
80%
Show 6 more adverse effects
1 of 7
75%
1 of 7
75%
1 of 7
80%
1 of 7
85%
1 of 7
80%
1 of 7
65%
Also reported in combinations. In the 16 25B-NBOMe reports where another drug was taken too, 5 mention hospital, emergency services or an overdose, 1 a seizure and 1 psychosis (too few reports for percentages). In the 17 single-substance reports: 3, 3 and 2. These are not in the figures above: they cannot be put down to 25B-NBOMe alone, and a mention is not always something that happened to the writer.
Combinations
Cross-Check 25B-NBOMe with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 4 positive 4 cautionary visit
I've tried 25i-NBOMe and 25c-NBOMe prior to this. I knew 25b would be amazing as well. The setting was in my room with easy access to music, drawing, and my computer. It was mainly a test to experiment this compound before doing it at another setting.
[Erowid Note: A first hand report of an experience and report of a fatality. From Reddit/r/Drugs . Reposted with permission. We have not yet received independent confirmation of this fatality, but believe it is factual.] This past Friday, I came home from classes around 2:30 PM and found my younger, 18-year-old brother...
Throughout the past 2 years, I've been a semi-regular user of numerous substances, to keep the list short I'll only mention the ones I've done more than 15-20 times, they include Ketamine, LSD, 4-MEC, 4-FA , shrooms, MDMA, cannabis of course, and a few other 'designer' amphetamines, so I'm not an expert by any means on...
To start, a bit about myself. I live in the UK, and got hold of some NBOMe series chemicals from what appeared to be a reputable website after having an interest in taking hallucinogens for a few years and doing a lot of research. In the end I ended up buying on a whim and, frankly, I wish I'd tried them earlier.
Set: Just woke up from 6 hours of sleep. Setting: Friday Afternoon, around my college town. Previous Experiences: Cannabis, 6-APB, MDMA, 4-AcO-DMT, 2C-E, 2C-T-2, 25C-NBOMe, 25I-NBOMe, Mushrooms, DMT, Amphetamine, 2C-I, 5-MeO-MiPT.
Background: For longer than I can remember I was on anti-depressants and high blood pressure medication. The combination literally drove me crazy. My speech became broken and fragmented and my life was dominated by lustful impassivity.
Desired effects: To go deeper than ever before Intensity: Overwhelming Source: RC vendor Iยve been experimenting with the NBOMe class of phenethylamines the past few months, mostly with 25C-NBOMe but also with 25I and 25B laid out as bottlers.
Bluelight 2 threads 1 positive 1 cautionary visit
I have a few mgs of this wonderful chem dissolved into a few ml of water. I decided I would put up this report as there appears to be literally no other accounts of it. The location I acquired it from suggested taking 2mg but I only took 1mg to be on the safe side.
Physical Background: I am overall physically healthy. -I have an ideal B.M.I. -I have stress related borderline hypertension. 130/80 mm/hg - 145/95 mm/hg -I am moderately physically active. I cycle one hour a day, walk one mile a day, and do very light strength training. -I have a balanced grain based diet.
Bluelight Reference Guide
Phenethylamines The Big & Dandy 25B-NBOMe (NBOMe-2C-B) Thread
Welcome to The Big & Dandy 25B-NBOMe Thread 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine Reagent drug test info for NBOMe compounds External Links: Wikipedia Entry Isomer Design Entry 25X-NBOMe, 25X-NBOH SAFETY MESSAGE This is a newly discovered group of chemicals, with little history of human...
Read full thread on Bluelight โ
25B-NBOMe's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has 25B-NBOMe, but its built-in entry only covers Insufflated, Sublingual. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "25B-NBOMe (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Duration (reference)
25B-NBOMe: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Insufflated duration: onset 1-4m ยท peak 8-12h ยท total 8-12h ยท after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 25B-NBOMe? Let us know. Reports are reviewed by moderators — this is not posted publicly.