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    Xanthines Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data

    Summary PsychonautWiki

    Xanthines (also known as substituted xanthines) are a chemical class of psychoactive substances derived from xanthine, an organic compound found in most human body tissues and fluids as well as in other organisms. Examples of xanthines include caffeine and theobromine. These are commonly used for their effects as both stimulants and bronchodilators.

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.5
    Strong 6/10

    Strong euphoria and anxiety/jitters with moderate focus and stimulation

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    10
    physical euphoria euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    Based on reports from:

    Tolerance

    Build-up develops over 1–2 weeks of daily use
    Reset 7–12 days of abstinence

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    →

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