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    Propylhexedrine Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 4 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • toxicity data (PsychonautWiki)

    Aliases: Obesin, Benzedrex, Propylhexadrine, Hexahdromethamphetamine

    Summary dose.wiki Erowid TripSit PsychonautWiki

    Propylhexedrine (also known as Benzedrex and Obesin) is a stimulant substance of the cycloalkylamine class. It is a structural analog of methamphetamine. Propylhexedrine is widely used medicinally as a nasal decongestant (for relief of congestion due to colds, allergies and allergic rhinitis) and sometimes used recreationally as an over-the-counter "legal high".

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Insufflated 10-30mg 30-75mg 75-100mg 100mg+
    Insufflated(Pure) 5-15mg 15-30mg 30-50mg 50mg+
    Oral(Benzedrex) 20-60mg 60-125mg 125-250mg 250mg+
    Oral(Pure) 30-60mg 60-120mg 120-180mg 180mg+
    Light Common Strong Heavy
    Sources

    Insufflated

    Dose ladder — TripSit

    Insufflated(Pure)

    Dose ladder — dose.wiki, TripSit

    Oral(Benzedrex)

    Dose ladder — TripSit

    Oral(Pure)

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Peak After Effects Total
    Insufflated 5-10 min 4-8 hrs 1-16 hrs 4-8 hrs
    Insufflated(Pure) 1-10 min 4-8 hrs 1-16 hrs 4-8 hrs
    Oral(Benzedrex) - 4-8 hrs 1-16 hrs 4-8 hrs
    Oral(Pure) - 4-8 hrs 1-16 hrs 4-8 hrs

    Effect Profile

    62 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 4.9
    Moderate+ 5/10

    Moderate focus with strong anxiety/jitters, mild stimulation and euphoria

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction

    Tolerance

    Build-up develops with repeated use, similar to amphetamines
    Reset 3–7 days

    Tolerance Decay

    Full tolerance 1d Half tolerance 5d Baseline ~14d

    Cross-Tolerances

    Effects Erowid Bluelight

    Aggregated from 15 single-substance Erowid and 47 Bluelight experience reports; 16 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 46

    80.7% (95% interval 69 to 89 percent) 87%
    66.2% (95% interval 54 to 77 percent) 87%
    43.6% (95% interval 32 to 56 percent) 84%
    42.6% (95% interval 30 to 57 percent) 86%
    38.3% (95% interval 26 to 53 percent) 85%
    23.4% (95% interval 14 to 37 percent) 80%
    21.0% (95% interval 13 to 33 percent) 83%
    19.1% (95% interval 10 to 32 percent) 81%
    14.5% (95% interval 8 to 25 percent) 79%
    8.5% (95% interval 3 to 20 percent) 85%
    6.4% (95% interval 2 to 17 percent) 80%
    6.4% (95% interval 2 to 17 percent) 78%
    6.4% (95% interval 2 to 17 percent) 85%
    6.4% (95% interval 2 to 17 percent) 88%
    4.3% (95% interval 1 to 14 percent) 88%
    4.3% (95% interval 1 to 14 percent) 90%
    4.3% (95% interval 1 to 14 percent) 80%
    4.3% (95% interval 1 to 14 percent) 82%
    4.3% (95% interval 1 to 14 percent) 88%
    4.3% (95% interval 1 to 14 percent) 85%
    Show 26 more positive effects
    4.3% (95% interval 1 to 14 percent) 88%
    4.3% (95% interval 1 to 14 percent) 90%
    2.1% (95% interval 0 to 11 percent) 70%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 70%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 70%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 75%

    Adverse Effects 52

    25.5% (95% interval 15 to 40 percent) 78%
    25.5% (95% interval 15 to 40 percent) 83%
    21.0% (95% interval 13 to 33 percent) 73%
    17.7% (95% interval 10 to 29 percent) 85%
    17.0% (95% interval 9 to 30 percent) 77%
    17.0% (95% interval 9 to 30 percent) 79%
    12.8% (95% interval 6 to 25 percent) 80%
    12.8% (95% interval 6 to 25 percent) 83%
    10.6% (95% interval 5 to 23 percent) 77%
    8.5% (95% interval 3 to 20 percent) 79%
    6.4% (95% interval 2 to 17 percent) 82%
    6.4% (95% interval 2 to 17 percent) 82%
    6.4% (95% interval 2 to 17 percent) 73%
    6.4% (95% interval 2 to 17 percent) 92%
    6.4% (95% interval 2 to 17 percent) 87%
    6.4% (95% interval 2 to 17 percent) 82%
    4.3% (95% interval 1 to 14 percent) 90%
    4.3% (95% interval 1 to 14 percent) 82%
    4.3% (95% interval 1 to 14 percent) 85%
    4.3% (95% interval 1 to 14 percent) 80%
    2.1% (95% interval 0 to 11 percent) 95%
    Show 31 more adverse effects
    4.3% (95% interval 1 to 14 percent) 72%
    4.3% (95% interval 1 to 14 percent) 80%
    4.3% (95% interval 1 to 14 percent) 80%
    4.3% (95% interval 1 to 14 percent) 75%
    4.3% (95% interval 1 to 14 percent) 72%
    4.3% (95% interval 1 to 14 percent) 82%
    4.3% (95% interval 1 to 14 percent) 78%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 70%
    2.1% (95% interval 0 to 11 percent) 75%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 90%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 85%
    2.1% (95% interval 0 to 11 percent) 80%
    2.1% (95% interval 0 to 11 percent) 80%

    Also reported in combinations. In the 16 Propylhexedrine reports where another drug was taken too, 0 mention hospital, emergency services or an overdose, 0 a seizure and 1 psychosis (too few reports for percentages). In the 15 single-substance reports: 2, 0 and 0. These are not in the figures above: they cannot be put down to Propylhexedrine alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check Propylhexedrine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 2 positive 2 neutral 4 cautionary visit
    A Long Account of a Great Experience positive exp #75149

    So finals season is coming into focus and I have quite a bit of work to do (books to read, papers to write, exams to study for, etc.). Usually around this time of year I will just find myself a few nights supply of adderall and get cracking with extreme focus and clarity.

    Seller Gates XVII
    All Night Libido-Fueled Stimulant Art Session neutral exp #119229

    TL;DR: Second time doing propylhexedrine ever, after a failed attempt in early 2019. Basically stayed up all night (8:34 AM as I’m typing this) drawing NSFW art and talking to friends. A bit of a ramble-y report, due to the nature of the drug class it belongs to LOL.

    feelwheel
    Temporarily Blind positive exp #114020

    Time of Experience: Early January 2020. Age: 19 Weight: 143 pounds Height: 6’0 Previous Drug Experience: Cannabis, caffeine LSD, 1P-LSD, diphenhydramine, dextromethorphan, 4-HO-MiPT, 4-HO-MET, 4-AcO-DMT, MDMA, kratom, Salvia divinorum, hawaiian baby woodrose seeds (LSA), nicotine/tobacco, alcohol, cocaine, heroin, code...

    Doubledoon · 125 mg oral / 125 mg oral / 160 mg oral / buccal
    Incredible Focus but Unpleasant Comedown cautionary exp #114837

    I regularly write down my experiences with different drugs and highs because I want to remember all the important parts of them and if I would want to try them again. I'd like to start this off by saying I'm regularly an incredibly unhappy person who will go to great lengths and a huge effort for a high.

    SayPerhapsToDrugs
    Powerfull cautionary exp #109627

    Propylhexedrine - Trial 1 - Date: 11/26/2016 Background Information: Currently living in a nursing home expected to be released soon to a group home. The Propylhexedrine was obtained from an over the counter inhaler, Benzedrex. The Propylhexedrine is cut into four pieces and then ingested.

    xdefiance · 1000 mg oral / 55 mg oral / 55 mg oral / joints/cigs smoked
    Good for Availability neutral exp #98111

    **NOTE** Everything that I say here in my experience report is from my personal experience with the drug. I often make reference to other stimulants. NOTHING I say should be interpreted as being applicable to others. Every body is different, so everyone reacts in unpredictable ways.

    PinKCloud · 250 mg oral / 1 g oral / 500 mg oral / 500 mg oral
    Never Again..... cautionary exp #95185

    I have tried Benzedrex inhalers many times before this experience. I used to be addicted to adderal, and I loved the speedy feeling. Benzedrex seemed to be the perfect substitute, until this happened. I was at home from college on a break when I stopped and picked up the inhaler.

    Aaron · 250 mg oral
    Seven Hours in the ER cautionary exp #75237

    I've tried benzedrex inhalers a few times. They keep me awake and alert and on occasion I've felt desperate enough to resort to them. I am an occasional recreational user of hard drugs. I do not use stimulants regularly. One day I decided to take 200mg of pure MDMA on a school night and stay up pretty late.

    Anonymous
    Bluelight 8 threads 2 positive 3 neutral 3 cautionary visit
    Benzedrex 700mg First Time Exactly Like Rolling And Tweaking At The Same Time neutral

    It was the end of august, I had just learned about benzedrex nasal inhaler a little bit ago by my best friend ever. Prolly would say i tryed it about end if august. I feel in love with this drug as soon as I did it. This thread is going to be a trip report. I would love hearing any crazy, and wild Benzedrex story's.

    700 mg mentioned in the thread; auto-extracted, unverified
    Propylhexedrine 250mg Cigar Cigarette Inexperienced Great Euphoric Head Buzz positive

    I took an unknown amount of Propylhexedrine (Henceforth PHX) acetate (Extracted in vinegar) equivalent to 250mg PHX, one wonderful, delicious, long, Romeo y Julieta Churchill length Cuban Cigar (If I had an unlimited supply of these, I don't think any other psychoactive would be in my safe, it is my one true love ), an...

    250 mg mentioned in the thread; auto-extracted, unverified
    Propylhexedrine 125 Mg First Time Pleasant Surprise positive

    Mods: please move to trip reports. Thanks. A couple of notes: I preserved some grammatical errors in here. Somehow, it seemed more true to my voice at the time. I submit this relatively mundane account just because there's a dearth of reports on propylhexedrine.

    125 mg mentioned in the thread; auto-extracted, unverified
    Last Resort Benzedrex What Wonders To Be Unveiled neutral

    *Disclaimer , (This is my First time) I am only a consumer of Benzedrex (*Footnote: in California, it's sold in CVS/Pharmacies and Walgreens) *Disclaimer(2) I am only doing this because I recently moved into another city and have NO connects whatsoever.

    Propylhexedrine First Time Up Up And Away cautionary

    Just thought I'd post a little sumthin' sumthin' on my first experience with Propylhexedrine, aka the mighty Benzedrex inhaler. First off just let me say that I spent the entire preceeding night researching this chemical--the pros and cons, dangers, methods of ingestion, trip reports, and anything else I could find.

    Benzedrex Legal High 250mg First Time And Educational Findings cautionary

    My Disclaimer: I am not a medical doctor and any information contained in this post is only my personal experience and is for educational purposes only. You agree to indemnify and hold harmless, both morally and legally, myself and Bluelight staff should you choose to imitate my actions.

    250 mg mentioned in the thread; auto-extracted, unverified
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Propylhexedrine, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Propylhexedrine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Insufflatedcommon ~ 52.5 mg
    • Insufflated(Pure)common ~ 22.5 mg
    Dose & duration (reference)
    Propylhexedrine: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Insufflated dose (mg): light 10-30 · common 30-75 · strong 75-100 · heavy 100+
    Insufflated(Pure) dose (mg): light 5-15 · common 15-30 · strong 30-50 · heavy 50+
    
    Insufflated duration: onset 5-10m · peak 4-8h · total 4-8h · after-effects 1-16h
    Insufflated(Pure) duration: onset 1-10m · peak 4-8h · total 4-8h · after-effects 1-16h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.