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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MDEA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: Mde, Eve

    Summary dose.wiki Erowid TripSit PsychonautWiki

    MDEA is a Schedule I controlled substance in most countries. The substance is characterized by a more sedating, 'stoning' quality compared to MDMA, with less emphasis on social connection and more on physical relaxation. MDEA requires careful dosing with an accurate milligram scale, adequate hydration without over-drinking, and temperature regulation in warm environments.

    Perspectives

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 70-120mg 120-180mg 180-225mg 225mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 18-60 min 12-30 min 1.5-2 hrs 1-2 hrs 12-48 hrs 3-6 hrs

    Effect Profile

    3 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 1.0
    Threshold 1/10

    Low headspace with mild body load

    Visual Intensity ×3
    0
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    5
    temperature regulation suppression teeth grinding increased heart rate
    Empathogen 4.4
    Moderate 4/10

    Moderate euphoria with mild stimulation and sensory enhancement, low empathy

    Empathy / Social Openness ×3
    3
    empathy, affection, and sociability enhancement
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    5
    stimulation teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 4.2
    Moderate 4/10

    Moderate euphoria with strong anxiety/jitters, mild stimulation, low focus

    Stimulation / Energy ×3
    4
    stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    3
    motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    8
    anxiety teeth grinding increased heart rate

    Tolerance

    No tolerance chart. No study has measured how long tolerance to it lasts, so this page shows what is known instead of a curve.

    No study has measured tolerance to MDEA in people. PsychonautWiki estimates that tolerance halves in 1-1.5 months and is gone in 2-3 months, without citing a source. What is known about repeat MDMA doses has not been tested for MDEA.

    Sources: PsychonautWiki: MDEA

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check MDEA with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 4 reports 1 positive 3 neutral visit
    Unique - Similar to, but Not Like MDMA neutral exp #89967

    Background: I first took mdma 9 years ago. I have strong experience with mdma, mda, lsd, mushrooms, mescaline (teas and the extracted hcl salt). I have extensive experience with numerous other drugs/psychedelics but that's not important to know for reading this experience so Iย’ll leave it at that for now.

    The Fresh Prince · 150 mg oral / 0.5 mg oral
    Connecting on New Years 99-00 positive exp #2017

    Material : The MDE was from a reliable source in the form of hard powder chunks in capsules. The certainty of material was pretty high. The MDE powder tastes bitter, especially strong on the front of the tongue. Zam thinks it tastes about the same as MDMA, while Zara thinks it's not quite as bitter as MDMA or 2CB.

    Zam · MDE · 150 mg oral
    Window To My Own Fears neutral exp #19141

    I was traveling across the country with a friend and came upon an old buddy of his who had purchased a jar of 'MDE'. I had never experienced this before and was curious to find out what, if any differance there might be from MDMA. After ingestion, the pill kicked in surprisingly fast, aprox. 15 minutes...FULL SWING.

    Cramer · MDE
    Clear and Centered neutral exp #2018

    Okay, so we took some of what we were told was MDE, to mark the new year. We are mostly sure that it was in fact MDE, but it's difficult to be sure. 12:27 am (T+ 0) - We threw down. The tablets were diamond-shaped, fairly small, with brown specks.

    Bug · MDE · 1 tablet oral
    Bluelight 3 threads 1 positive 2 neutral visit
    Mdea 50 Mg 100 Mg First Time The Guinea Pig Friend neutral

    i thought i'd share this here since MDEA trip reports are so rare to find online. the MDEA was pure, not a pressed pill. so enclosed are 2 trip reports. the first is a trip report by my friend. then under the "======" break is my trip report.

    50 mg, 100 mg mentioned in the thread; auto-extracted, unverified
    Mdea First Time Definitely A Fun Drug positive

    my first MDEA experiance, i was sold crystals which were openly sold as MDEA not MDMA or MDA, they were rather cheap $50 canadian, for a gram so i bought a gram and split it with 2 friends the experiance is as follows: T0:00-weight out 200mgs each and wash it down with some water T0:30-starting to feel pretty floored h...

    Mde 350mg Inexperienced Complete Bliss neutral

    MDEA(MDE) - 350mg experienced Most people i have come across on these forums seem to beleive MDE is nothing more then some sort of inerior cousin to MDMA. I have personally found this drug to be just as enjoyable experience as MDMA, although it is more of a "stoned" type high as opposed to a light as feathers dancy ecs...

    350 mg mentioned in the thread; auto-extracted, unverified

    PiHKAL / TiHKAL Shulgin

    PiHKAL #106: MDE

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    โ€” Alexander Shulgin, PiHKAL (with 100 mg)
    →

    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes MDEA, but its built-in data can be thinner than ours. Importing this file adds a separate "MDEA (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.

    ⬇ Download import file Import this file as custom substances and you get "MDEA (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.