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    MDEA molecular structure

    MDEA Stats & Data

    Mde Eve
    PubChem
    MW207.27
    FormulaC12H17NO2
    LogP2.5
    IUPAC1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine
    SMILESCCNC(C)CC1=CC2=C(C=C1)OCO2
    InChIKeyPVXVWWANJIWJOO-UHFFFAOYSA-N
    Chemical Class Substituted amphetamine
    Psychoactive Class Psychedelic / Stimulant

    Receptor Profile

    Receptor Actions

    Inhibitors
    Serotonin-dopamine-norepinephrine reuptake inhibitor (SNDRI)
    Other
    Serotonin-dopamine-norepinephrine releasing agent (SNDRA)

    Toxicity

    PsychonautWiki

    Short-term physical health risks of MDEA consumption include dehydration, insomnia, hyperthermia, and hyponatremia. Continuous activity without sufficient rest or rehydration may cause body temperature to rise to dangerous levels, and loss of fluid via excessive perspiration puts the body at further risk as the stimulatory and euphoric qualities of the drug may render the user oblivious to their energy expenditure for quite some time. Diuretics such as alcohol may exacerbate these risks further. The exact toxic dosage is unknown, but considered to be far greater than its active dose.

    Organ-specific toxicity

    As with MDMA, the neurotoxicity of MDEA use has long been the subject of debate. Scientific study has resulted in the general agreement that, although it is physically safe to try in a responsible context, the administration of repeated or high dosages of MDEA is likely to be neurotoxic and cardiotoxic in some form. Like other powerful serotonin releasing agents, MDEA is thought to cause down-regulation of serotonin reuptake transporters in the brain.

    Effect Profile

    Curated + 3 Reports
    Psychedelic 1.0

    Low headspace with mild body load

    Visual Intensity×3
    0
    Headspace Depth×3
    1
    Auditory Effects×1
    0
    Body Load / Somatic Effects×1
    5
    Empathogen 4.4

    Moderate euphoria with mild stimulation and sensory enhancement, low empathy

    Empathy / Social Openness×3
    3
    Euphoria / Mood Elevation×2
    6
    Stimulation×1
    5
    Sensory Enhancement×1
    5
    Stimulant 4.2

    Moderate euphoria with strong anxiety/jitters, mild stimulation, low focus

    Stimulation / Energy×3
    4
    Euphoria / Mood Lift×2
    7
    Focus / Productivity×2
    3
    Anxiety / Jitters×1
    8

    Tolerance & Pharmacokinetics

    drugs.wiki

    No tolerance chart. No study has measured how long tolerance to it lasts, so this page shows what is known instead of a curve.

    No study has measured tolerance to MDEA in people. PsychonautWiki estimates that tolerance halves in 1-1.5 months and is gone in 2-3 months, without citing a source. What is known about repeat MDMA doses has not been tested for MDEA.

    Sources: PsychonautWiki: MDEA

    Experience Report Analysis

    Erowid
    9 Reports
    3 Single-substance
    2000–2012 Date Range
    2 With Age Data

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 9 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Not Specified 2 of 9
    • Male 5 of 9
    • Female 2 of 9

    Age Distribution

    Reports Over Time

    Real-World Dose Distribution

    Erowid

    From 7 of 12 recorded dose entries: those that state a weight (mg, g or µg), in routes with at least five of them. Values above Q3 + 3×IQR, far above what people typically take, are left out; they can include real heavy doses and overdoses, not only mistakes.

    Oral (n=7)

    Median: 100.0mg 25th: 100.0mg 75th: 137.5mg 90th: 150.0mg

    Form / Preparation

    Most common forms and preparations, as a share of the 7 reports that give one

    Too few reports for bars: these forms come from 7 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Capsule 4 of 7
    • Pill / Tablet 2 of 7

    Legal Status

    Controlled internationally under the UN Convention on Psychotropic Substances 1971.
    Country Status Notes
    Austria MDEA is illegal to possess, produce and sell under the SMG (Suchtmittelgesetz Österreich).
    Brazil MDEA is illegal to possess, produce or sell as it is listed on Portaria SVS/MS nº 344 as "MDE".
    Canada MDEA is listed on the CSDA in Schedule I.
    France MDEA is scheduled as a "stupéfiant", i.e. a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture.
    Germany MDEA is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of April 15, 1991. It is illegal to manufacture, possess, import, export, buy, sell, procure or to dispense it without a license. ( MDE )
    Switzerland MDEA is a controlled substance specifically named under Verzeichnis D.
    United Kingdom MDEA is a Class A drug.
    United States In the United States, MDEA was introduced recreationally in 1985 as a legal substitute to the newly banned MDMA. MDEA was made a Schedule 1 substance in the United States on October 15, 1987.
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