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    Disclaimer
    ⚠ Barbiturates have a narrow therapeutic window and high overdose risk. Combining with alcohol or other depressants can be fatal.

    Hexobarbital Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • PubChem toxicity data
    • classified Tentative

    Summary TripSit

    Is a barbiturate that was once used for inducing anesthesia for surgery. It has a very rapid onset, and a short duration of effects.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 10-15mg 15-20mg 20-30mg 30mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 1-2 min 30-45 min 1-4 hrs 30-45 min

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually. With barbiturates, you get used to the effects much more than to a dangerous dose, so the gap between a dose that works and one that kills shrinks the more you use. Stopping suddenly after regular use can cause convulsions and delirium.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder · Phenobarbital label: drug abuse and dependence

    Effects

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    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Hexobarbital there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Hexobarbital (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Hexobarbital
    Unit
    mg
    Description
    Hexobarbital
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): light 10-15 · common 15-20 · strong 20-30 · heavy 30+
    
    Oral duration: onset 1-2m · peak 30-45m · total 30-45m · after-effects 1-4h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 17.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.