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    Gabapentin Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • toxicity data (PsychonautWiki, PubChem)

    Aliases: Gralise, Gabbies, Gabarone, Neurontin

    Summary dose.wiki Erowid TripSit PsychonautWiki

    Gabapentin (also known as Neurontin) is a depressant substance of the gabapentinoid class. It is a structural analog of the neurotransmitter GABA and acts by inhibiting certain calcium channels in the brain, namely α2δ subunit-containing voltage-dependent calcium channels (VGCCs). Gabapentin was originally developed to treat epilepsy and is currently FDA approved to treat postherpetic neuralgia in adults and as an adjunctive therapy in the treatment of partial onset seizures.

    Dose Information dose.wiki

    ROA Light Common Strong Heavy
    Oral BA 27%-60% 200-600mg 600-900mg 900-2400mg 2400mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki Bioavailability 27%-60% — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 0.5-2 hrs 2-3 hrs 2-4 hrs 12 hrs 5-7 hrs

    Tolerance

    Build-up develops over 1–2 weeks of daily use
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Cross-Tolerances

    Effects Erowid Bluelight

    Aggregated from 111 single-substance Erowid and 31 Bluelight experience reports; 67 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 56

    45.2% (95% interval 29 to 62 percent) 80%
    42.9% (95% interval 35 to 51 percent) 89%
    30.3% (95% interval 23 to 38 percent) 80%
    26.0% (95% interval 20 to 34 percent) 83%
    16.9% (95% interval 12 to 24 percent) 80%
    16.1% (95% interval 7 to 33 percent) 85%
    16.1% (95% interval 7 to 33 percent) 81%
    16.1% (95% interval 7 to 33 percent) 84%
    16.1% (95% interval 7 to 33 percent) 76%
    15.5% (95% interval 10 to 22 percent) 82%
    15.5% (95% interval 10 to 22 percent) 87%
    12.9% (95% interval 5 to 29 percent) 85%
    12.9% (95% interval 5 to 29 percent) 86%
    12.9% (95% interval 5 to 29 percent) 81%
    12.9% (95% interval 5 to 29 percent) 76%
    12.7% (95% interval 8 to 19 percent) 88%
    10.6% (95% interval 6 to 17 percent) 81%
    10.6% (95% interval 6 to 17 percent) 81%
    9.7% (95% interval 3 to 25 percent) 80%
    9.7% (95% interval 3 to 25 percent) 85%
    Show 36 more positive effects
    9.7% (95% interval 3 to 25 percent) 80%
    7.7% (95% interval 4 to 13 percent) 68%
    7.0% (95% interval 4 to 12 percent) 85%
    6.5% (95% interval 2 to 21 percent) 78%
    6.5% (95% interval 2 to 21 percent) 75%
    6.5% (95% interval 2 to 21 percent) 88%
    6.5% (95% interval 2 to 21 percent) 85%
    6.5% (95% interval 2 to 21 percent) 90%
    6.5% (95% interval 2 to 21 percent) 92%
    6.5% (95% interval 2 to 21 percent) 82%
    6.5% (95% interval 2 to 21 percent) 85%
    5.6% (95% interval 3 to 11 percent) 87%
    Auditory Effects 5.6% (95% interval 3 to 11 percent) 70%
    4.2% (95% interval 2 to 9 percent) 78%
    4.2% (95% interval 2 to 9 percent) 90%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 90%
    3.2% (95% interval 1 to 16 percent) 95%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 90%
    3.2% (95% interval 1 to 16 percent) 90%
    3.2% (95% interval 1 to 16 percent) 70%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 70%
    3.2% (95% interval 1 to 16 percent) 95%
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 90%

    Adverse Effects 21

    16.1% (95% interval 7 to 33 percent) 83%
    13.4% (95% interval 9 to 20 percent) 82%
    12.9% (95% interval 5 to 29 percent) 72%
    9.1% (95% interval 5 to 15 percent) 85%
    8.4% (95% interval 5 to 14 percent) 75%
    6.3% (95% interval 3 to 12 percent) 78%
    5.4% (95% interval 2 to 11 percent) –
    3.6% (95% interval 1 to 9 percent) –
    3.6% (95% interval 1 to 9 percent) –
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 75%
    3.2% (95% interval 1 to 16 percent) 90%
    3.2% (95% interval 1 to 16 percent) 85%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 80%
    3.2% (95% interval 1 to 16 percent) 75%
    Show 1 more adverse effect
    3.2% (95% interval 1 to 16 percent) 80%

    Also reported in combinations. In the 67 Gabapentin reports where another drug was taken too, 8 (11.9%) mention hospital, emergency services or an overdose, 3 (4.5%) a seizure and 3 (4.5%) psychosis. In the 111 single-substance reports: 9.9%, 5.4% and 0.9%. These are not in the figures above: they cannot be put down to Gabapentin alone, and a mention is not always something that happened to the writer.

    Combinations

    Cross-Check Gabapentin with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Reddit 2 reports 2 neutral visit
    Gabapentin is f****** weird neutral r/gabagoodness ▲56 62 comments

    Downed 900mg 3 hours ago thinking I wasn’t going to feel anything. I don’t really get that uplifting euphoria from Phenibut anymore so I figured I’d give Gabapentin a shot. This is some altogether different shit. This is what a lobotomy must feel like.

    u/anonymous · 2022-08-04
    I could get used to this neutral r/gabagoodness ▲46 51 comments

    I was prescribed gaba for anxiety and paranoia. Without getting too much into it I'm a vet and I'm always on high alert. My doc gave me a pretty low dose to start with. After browsing this board i took my morning dose with peanut butter.

    u/Arrpee88 · 2024-03-12
    Erowid 8 reports 3 positive 2 neutral 3 cautionary visit
    Subtly Enjoyable to Wonderful positive exp #83751

    I came by 2400mg of gabapentin (neurontin) in 100mg capsules and decided to do a bit of experimenting with it. I did some reading on the drug and decided to take 800mg and to not drink or supplement with other drugs. I wanted to know what this gabapentin was all about.

    Wdpwg · Gabapentin (Neurontin) · 600 mg insufflated / 200 mg oral / 1 glass oral / 400 mg oral
    Bedroom Gag cautionary exp #36553

    One night I was desperate to snort something other then cocaine so I decided to snort some Neurontin that my doctor had just prescribed me. When I realized how much I was going to have to snort, I decided to just snort 2 of the 300mg pills then swallow the rest. Snorting the pills was not pleasant.

    Turtle lady · Gabapentin (Neurontin) · 600 mg insufflated / 900 mg oral
    Saved My Life During Opiate Withdrawal cautionary exp #80581

    Ok, I've been struggling with opiate addiction for close to 5 years. It started during my time off work due to carpal tunnel syndrome and I was prescribed 180 Lorcet 10mg per month.

    BrockLanders · Gabapentin (for Opiate Dependency) · 1200 mg
    Early Explorations of a Novel Hallucinogen neutral exp #110836

    This trip report is not going to be incredibly long or detailed, but I have gotten to a point of experimentation with and appreciation of this molecule that I felt I needed to get my thoughts about it down so far and make a log of what I have already experienced.

    Kaleida
    Glimpsing Mythological Realms neutral exp #111012

    This was my eleventh experience with gabapentin, and it was my most hallucinogenic yet, so I felt compelled to write a report about it, though the meat of it won't be incredibly long.

    Kaleida
    The World is Shiny positive exp #79323

    So about 6 months ago, I was prescribed gabapentin, because my psychiatrist wanted me to get off of using quetiapine (an antipsychotic) for sleep. He recommended taking 300 mgs the first night, and if that didn't work, 600 mgs the next night, and then up to the maximum I was supposed to take, 900 mgs.

    GoodyTwoShoes · 1.8 g oral / 600 mg oral / 300 mg oral / 300 mg oral
    Good or Bad? positive exp #78294

    Okay, I found a HUGE bottle (275 pills) of Gabapentin 600mg in his dead grandpa’s bathroom. Knowing that my grandpa wouldn’t mind, I took a good handful, not even knowing what they were, but did some extensive research on the internet and decided to try a trip.

    Light Enigma · Gabapentin (Neurotin) · repeated oral
    Not Worth It for the Long Term cautionary exp #97247

    In late 2007 or early 2008 I was referred to a neurologist and Was prescribed Neurontin (Gapapentin) for severe Neuropathic Pain. While I've never been diagnosed with a specific condition, I have struggled with severe nerve pain, insomnia as well as depression and other symptoms.

    bfabbb · oral / oral
    Bluelight 7 threads 1 positive 5 neutral 1 cautionary visit
    Megadose Of Gabapentin positive

    I found a bunch of bottles of unused gabapentin at my grandfathers house and read into the highest dose and wanted to break the record lol. I've taken lyrica many times and enjoyed it thoroughly. I've also done lower doses of gabapentin and not enjoyed it very much so I thought I'd try a higher dose.

    6 g mentioned in the thread; auto-extracted, unverified
    Gabapentin Retrospective Early Explorations Of A Novel Hallucinogen neutral

    This trip report is not going to be incredibly long or detailed, but I have gotten to a point of experimentation with and appreciation of this molecule that I felt I needed to get my thoughts about it down so far and make a log of what I have already experienced.

    Gabapentin 3600 Mg Eleventh Time Glimpsing Mythological Realms neutral

    This was my eleventh experience with gabapentin, and it was my most hallucinogenic yet, so I felt compelled to write a report about it, though the meat of it won't be incredibly long.

    3600 mg mentioned in the thread; auto-extracted, unverified
    Neurontin Gabapentin First Time Mild Ecstacy Like High But With No Edge neutral

    Neurontin (Gabapentin) - First Time - Mild, Ecstacy-like high, but with no "edge" Drug description and dosage: Five 300 mg capsules: (Size B capsules with yellow opaque body and cap), taken orally, in my case, with a very heavy breakfast., followed by seven more 300mg capsules over 3 1/2 hours, for a total dosage of 36...

    Neurontin Gabapentin 1200mg I Dont Want To Feel The Realness Of Life neutral

    Warning long post and I hope I do this right My usage experience specifically with Neurontin - 2 years continuous use of prescribed dose of 400 mg each night for restless leg syndrome (rls) stopped for one year and now prescribed to me again at 400 mg nightly. I've been on it for a week now.

    1200 mg mentioned in the thread; auto-extracted, unverified
    Gabapentin Take Medically But Going For Recreation 1st Time Im Really Suprised cautionary

    Background: I regularly take 800mg B.I.D. (twice a day) for (extremely) treatment resistant depression/anxiety/ptsd, along with the following (I know it's a lot): 120mg Cymbalta 300mg Lamictal 45mg Remeron 400mg Seroquel XR 50mg Seroquel as needed for anxiety (1-2 times per day avg.) 150mg Hydroxyzine as needed for anx...

    Pill Identifiers

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    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Gabapentin, but its built-in data can be thinner than ours. Importing this file adds a separate "Gabapentin (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.

    ⬇ Download import file Import this file as custom substances and you get "Gabapentin (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.