DMO-PHP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 3,4-dmohp, 3,4-dimethoxy-ฮฑ-php
Summary
Extremely limited human data. All dosage and duration figures are extrapolated from user reports and close structural analogues (ฮฑ-PHP, ฮฑ-PVP, MDPV). Functions as a potent dopamine and norepinephrine transporter inhibitor; serotonin activity appears minimal.
Dose Information
Dose basis. Approximate ranges compiled from user reports of DMOโPHP and close analogs (ฮฑโPHP/ฮฑโPVP). Identity/potency vary; start low and verify with drug checking. Avoid frequent redoses due to compulsion and cardiovascular strain. Irritates nasal mucosa; increases vasoconstriction and blood pressure more than oral; higher compulsion risk. User-reported data only. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-40mg | 40-60mg | 60mg+ |
| Insufflated | 5-15mg | 15-30mg | 30-50mg | 50mg+ |
| Smoked | 3-10mg | 10-20mg | 20-30mg | 30mg+ |
Sources
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 1-2.5 hrs | 1-2 hrs | 2.75-6.25 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-2.5 hrs | 1-2 hrs | 2.25-5 hrs |
| Smoked | 0-2 min | 5-15 min | 1-2.5 hrs | 1-2 hrs | 2.08-4.78 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiety/jitters with moderate focus, low stimulation
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance appears to build rapidly over multiโday use (as with ฮฑโPVP/MDPV) and decays over weeks; figures are approximate and based on patterns reported for structurally similar pyrrolidinophenones rather than controlled studies. Space sessions by multiple weeks to limit escalation and psychosis risk.
Cross-Tolerances
Effects
Effect glossary — · full glossary
Combinations
Cross-Check DMO-PHP with another substanceHelpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track DMO-PHP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
DMO-PHP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 5 ยท light 10-20 ยท common 20-40 ยท strong 40-60 ยท heavy 60+ Insufflated dose (mg): threshold 2 ยท light 5-15 ยท common 15-30 ยท strong 30-50 ยท heavy 50+ Smoked dose (mg): threshold 1 ยท light 3-10 ยท common 10-20 ยท strong 20-30 ยท heavy 30+ Oral duration: onset 15-45m ยท come-up 0.5-1h ยท peak 1-2.5h ยท offset 1-2h ยท total 2.75-6.25h ยท after-effects 6-24h Insufflated duration: onset 5-10m ยท come-up 10-20m ยท peak 1-2.5h ยท offset 1-2h ยท total 2.25-5h ยท after-effects 6-24h Smoked duration: onset 0-2m ยท come-up 5-15m ยท peak 1-2.5h ยท offset 1-2h ยท total 2.08-4.78h ยท after-effects 6-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 30 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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