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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Afloqualone Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • classified Tentative
    • classified Research-chemical

    Aliases: Aroft, Hq-495, Arofuto

    Depressant Research-chemical

    Summary dose.wiki TripSit

    Potent photosensitizer - sun/UV exposure can precipitate severe dermatitis; cover skin and use high-SPF sunscreen. Marked ataxia and motor incoordination appear at higher doses with increased risk of falls. Mixing with any other CNS depressant markedly increases risk of respiratory depression.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-75mg 75-100mg 100-200mg 200mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Peak Offset After Effects Total
    Oral 30-90 min 1.5-3 hrs 2-4 hrs 2-6 hrs 3-5 hrs

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Cross-Tolerances

    Benzodiazepines
    Barbiturates
    Methaqualone
    Other GABA_A PAMs

    Effects dose.wiki TripSit

    Positive
    Negative
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral
    Afloqualone's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 dose.wiki 📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Afloqualone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Afloqualone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Afloqualone
    Unit
    mg
    Description 
    Afloqualone
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 50-75 · common 75-100 · strong 100-200 · heavy 200+

Oral duration: onset 0.5-1.5h · peak 1.5-3h · offset 2-4h · total 3-5h · after-effects 2-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 87.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.