Methaqualone Well-documented

Well-documented

Multiple authoritative sources agree on dosing and effects.

5 corroborating sources

2 ROAs with full dose ladders

duration data present

toxicity data (PsychonautWiki)

Aliases: 714s, Sopor, Ludes, Quack, Parest, quaaludes, qualudes, mandrax

Summary PsychonautWiki

Methaqualone (brand name Quaalude in the US and Mandrax in the UK) is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. The sedative–hypnotic activity of methaqualone was first noted by researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.

Dose Information dose.wiki

ROA	Light	Common	Strong	Heavy
Oral	75-150mg	150-300mg	300-500mg	500mg+
Smoked	50-100mg	100-200mg	200-300mg	300mg+

Light Common Strong Heavy

Sources

Oral

Dose ladder — dose.wiki

Smoked

Dose ladder — dose.wiki, PsychonautWiki

⚠ above 300 mg oral Dangerous for first-time users

☠ around 8 g/day oral Can be fatal (tolerance-dependent)

“Taking doses of over 300mg can be dangerous for first time users.” — toxicity literature
“Depending on the state of the user's individual tolerance, doses of about 8,000mg per day can be fatal whilst others on even higher doses (of up to 20,000mg) may survive.” — toxicity literature

Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	20-45 min	30-60 min	2-4 hrs	2-4 hrs	6-12 hrs	5-8 hrs
Smoked	-	-	-	-	4-6 hrs	1-2 hrs

Tolerance

Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use

Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

Cross-Tolerances

Barbiturates

Benzodiazepines

Other sedative-hypnotics

Effects Erowid

Aggregated from 13 single-substance Erowid experience reports; 8 Erowid reports where another drug was taken too are left out

Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

Too few reports for bars: these effects come from 13 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

Positive Effects 2

5 of 13 –

4 of 13 –

Adverse Effects 2

5 of 13 –

3 of 13 –

Also reported in combinations. In the 8 Methaqualone reports where another drug was taken too, 0 mention hospital, emergency services or an overdose, 1 a seizure and 0 psychosis (too few reports for percentages). In the 13 single-substance reports: 1, 0 and 0. These are not in the figures above: they cannot be put down to Methaqualone alone, and a mention is not always something that happened to the writer.

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 8 reports 3 positive 4 neutral 1 cautionary visit

A Pleasant Surprise, Overall Lovely Compound positive exp #115456

A Pleasant Surprise and Glowing Experience This experience took place in my residence, where I was undisturbed. To preface I have been searching for Methaqualone for quite some time, though like many newer researchers I assumed I would never have the opportunity to try it given its production history.

Synthesis and Effects neutral exp #114521

Methaqualone About 10 years ago I was able to acquire some ortho-toluidine from which I made a number of small batches of Methaqualone. The synthesis went basicly as described by cheapskate on the net.

Quaaland neutral exp #23677

FEW QUICK NOTES Ive noticed the last time I submitted a report for Quaaludes that I was only the second submitter. I wanted to change that. There arent enough reports on methaqualone. Especially, there arent any reports for methaqualone alone [INTRODUCTION + PART 1].

I Was In Heaven cautionary exp #24492

I was home alone, looking for something to do. Since being home alone is very unusual for me, I usually do some sort of illicit substance. However, I was tapped out of every substance I usually have. I searched my brother's and sister's rooms, but, alas, I couldn't find anything.

Quaaduds Deadludes ...or Not.... positive exp #105008

At the time of writing this, its been about 5 hours since first ingesting the first capsule (300mg). My friends and I recently acquired Methaqualone powder, and were beyond excited to try out this legendary drug.

The Best He Had Ever Felt neutral exp #35368

I did not have a lot of experience with Quaaludes when they were legal (1961 - 1984 or during the bootleg period of 1984 - 1988). I had taken them a few times, but in all likelyhood the ones I had taken over a decade ago were most likely large doses of Valium (diazapam).

A Thorough Exploration positive exp #115836

Having a good friend of mine who is a talented organic chemist, I have had the opportunity to thoroughly experiment with Methaqualone (Quaalude) over the last 2 years. The material was LCMS tested and was in excess of 99% purity and the real deal, not some RC analogue.

Smoke Of God Or Satan? neutral exp #20671

Where I come from, South Africa, this drug is not taken orally as it's done in the rest of the world our country has a much more interesting aproach, smoking it. Methaqualone or Mandrax as it is reffered to here is the most used drug in South Africa.

Bluelight 2 threads 2 positive visit

Methaqualone First Time An Experience With Quaalude Methaqualone positive

I figured I'd write up a little something, because before I took my first pill last night, I struggled to find many accounts of the experience (likely due to the rarity of the drug). Thus, I figured I'd share my experience and bring some insight to the masses.

Methaqualone 750mg First Experience The Cosby Show positive

Date: July 25, 2015 Time: 11:00PM - 4:00AM Drug: Methaqualone Dose: 750mg The list of drugs I expected to never get the chance to try is dwindling pretty quickly.

Methaqualone's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

💊 Pill Identifier 📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki 📖 TripSit

Import into PsychonautWiki Journal

The PsychonautWiki Journal app includes Methaqualone, but its built-in data can be thinner than ours. Importing this file adds a separate "Methaqualone (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.

⬇ Download import file Import this file as custom substances and you get "Methaqualone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

Ranges are harm-reduction guidance, not a prescription.

Report an issue or suggest an edit

Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Methaqualone? Let us know. Reports are reviewed by moderators — this is not posted publicly.

Methaqualone Well-documented Well-documented Multiple authoritative sources agree on dosing and effects. 5 corroborating sources 2 ROAs with full dose ladders duration data present toxicity data (PsychonautWiki)