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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-METHYLAMINOREX Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • classified Tentative
    • classified Research-chemical

    Summary

    A very potent stimulant that has quite a long duration of action at around 16 hours.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 1-5mg 5-10mg 10-15mg 15mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 5-15 min 14-18 hrs 1-24 hrs 14-18 hrs

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 2d Half tolerance 7d Baseline ~14d

    Quantitative tolerance kinetics are not formally characterized in humans; estimates reflect typical stimulant patterns and community observations (tolerance builds over multi‑day binges and partially resolves over 1–3 weeks). Avoid consecutive‑day use to reduce bingeing and sleep deprivation.

    Cross-Tolerances

    Amphetamine-like stimulants (e.g., amphetamine, methamphetamine)
    Other aminorex analogues (e.g., 4,4′‑DMAR)

    Effects Erowid

    Aggregated from 10 single-substance Erowid experience reports; 2 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 10 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 3

    7 of 10 –
    4 of 10 –
    3 of 10 –

    Adverse Effects 0

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 6 positive 2 neutral visit
    Euphoric & Efficient positive exp #2153

    It is most likely available in larger urban areas, but is quite uncommon. You need to be pretty well connected to get it. Boiling point is very low. You can smoke it by placing about 10 mg on aluminum foil, and holding a lighter under the foil to warm it.

    Anonymous · 4-methylaminorex · 10 mg smoked
    Somewhere Between Meth and MDMA, Yet Unique positive exp #15255

    Drug: 4-methylaminorex, aka 'Ice', a member of the oxazoline family Dose: 30 mg orally (at t = 0:00), 30 mg snorted (at t = 1:00) Duration: time to kick in -- 15 min, come up -- 2 hours, plateau -- 3 hours, come down (effects still quite strong) -- 3 hours, come down (effects minimal) -- 3.5 hours TOTAL = 11.5 hours Ex...

    fairnymph · 4-Methylaminorex · 30 mg oral / 30 mg insufflated
    Parallels with Meth & MDMA positive exp #15294

    I had heard about Ice (4-methylaminorex) and it caught my attention. It seemed almost too good to be true, and also extremely rare. I had also been interested in methamphetamine so when I found an 'Ice' connection I naturally jumped at the chance.

    yasmapal · 4-Methylaminorex · smoked
    A Cheerful and Productive Day positive exp #36337

    4-methylaminorex experiment: let's clean the house! Time: 10:20 a.m. on a Saturday My household just left for Burning Man, so I want to start off my week of blissful solitude by getting the entire house clean.

    bevz · 4-Methylaminorex · 12 mg insufflated
    Not A Substitute neutral exp #17720

    I was only able to try 4-MAR once, and obtained from a sysntesis 1.5g of product, yields were much lower then expected. 4-MAR when compared to methamphetamine, in tolerant daily methamphetamine users, took away the desire to use meth during the duration of it's use.

    Chicken · 4-Methylaminorex
    Working on 4-Methylaminorex positive exp #15935

    10:10 AM: 20 mgs 4methylaminorex insuf After finishing my morning phone conference, I opened up a gel cap that a friend had brought up for me. It was labeled 20 mgs and I didn't brother to reweigh it.

    maison · 4-Methylaminorex · 20 mg insufflated
    Euphoria of the Dick positive exp #106177

    I was at the social security building getting my food stamp card renewed when an attractive Hispanic chick walks up to me and tell me she wants to parrtay. This happened on the way out of the building so I didn't have an excuse to say no.

    Adam A. · 4-Methylaminorex · smoked
    Mild, Long-Lasting Entheogenic Stimulant neutral exp #12684

    I ate about 10 mg of 4-Methylaminorex powder at around 10 AM on a weekday. Did not have a scale. The drug was introduced to me as a study aid, a material good for overcoming writer's block (or other creative blocks), something useful for getting lots of work done, especially intellectual work.

    Samanthe · 4-Methylaminorex · 10 mg oral
    →

    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 4-METHYLAMINOREX there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "4-METHYLAMINOREX (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    4-METHYLAMINOREX
    Unit
    mg
    Description
    4-METHYLAMINOREX
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 1 Β· light 1-5 Β· common 5-10 Β· strong 10-15 Β· heavy 15+
    
    Oral duration: onset 5-15m Β· peak 14-18h Β· total 14-18h Β· after-effects 1-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 7.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.