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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-MeO-PCPY Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 2 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Dissociative Research-chemical

    Summary TripSit

    3-Methoxy analogue of Rolicyclidine (PCPy) less opioid effects than Phenylcyclidine (PCP) Yet still prominent.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Insufflated 1-3mg 3-6mg 6-10mg 10mg+
    Oral 2-4mg 4-8mg 8-15mg 15mg+
    Light Common Strong Heavy
    Sources

    Insufflated

    Dose ladder — dose.wiki, TripSit

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 15-45 min 3-5 hrs 1-6 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 2.0
    Light 2/10

    Low dissociative depth with strong mania, low motor impairment

    Dissociative Depth ×3
    2
    derealization
    ⚠ Mania / Compulsion ×1
    10
    compulsive redosing disinhibition stimulation euphoria
    Insight / Novel Thought ×2
    0
    ⚠ Motor / Sensory Impairment ×1
    2
    numbness
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives
    Ketamine
    PCP
    Methoxetamine

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check 3-MeO-PCPY with another substance

    3-MeO-PCPY's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 3-MeO-PCPY there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "3-MeO-PCPY (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    3-MeO-PCPY
    Unit
    mg
    Description 
    3-MeO-PCPY
Source: SubstanceSearch (substancesearch.com)

Insufflated dose (mg): light 1-3 · common 3-6 · strong 6-10 · heavy 10+
Oral dose (mg): light 2-4 · common 4-8 · strong 8-15 · heavy 15+

Insufflated duration: after-effects 1-6h
Oral duration: onset 15-45m · peak 3-5h · after-effects 1-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 4.5 mg (Insufflated).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.