I plugged, I swallowed and snorted, 500 milligrams went down the hatch, of the latest UK legal Arylcyclohexylamine! 3-MeO-PCMo HCl (RC name) 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (IUPAC name) Substance came as white, glassy crystalline lumps.
3-MeO-PCMo
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Pcmo
Summary
3-MeO-PCMo (4-[1-(3-methoxyphenyl)cyclohexyl]morpholine) is a new morpholine analogue of 3-MeO-PCP. It is a dissociative NMDA receptor antagonist, sigma receptor agonist and anesthetic drug of the arylcyclohexylamine chemical class with a potency of less than 1/10th of that of 3-MeO-PCP. This compound induces a state referred to as "dissociative anesthesia" when ingested and is therefore used as a recreational drug.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-80mg | 80-125mg | 125-150mg | 150mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 2-3 hrs | 1-2 hrs | 5-6 hrs |
| Insufflated | 4-15 min | 1-2 hrs | 1-2 hrs | 3-5 hrs |
Effect Profile
2 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
5.4
Moderate+
5/10
Strong dissociative depth with strong mania and motor impairment, mild insight
Dissociative Depth
×3
10
depersonalization
derealization
consciousness disconnection
physical disconnection
cognitive disconnection
visual disconnection
+5 more
Mania / Compulsion
×1
10
mania
compulsive redosing
disinhibition
increased energy
stimulation
Insight / Novel Thought
×2
4
conceptual thinking
creativity enhancement
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
spatial disorientation
visual disconnection
double vision
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
3d
Half tolerance
7d
Baseline
~28d
Pattern inferred from dissociative-class use; high uncertainty due to sparse PCMo-specific data. Many user reports suggest meaningful cross-tolerance within arylcyclohexylamines; long spacing between sessions (2–6 weeks) helps restore sensitivity.
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
Combinations
Cross-Check 3-MeO-PCMo with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 2 reports 2 neutral visit
As a US resident, I (note: 'i', 'he', 'her', 'it', 'them' should be thrown out of our vocabulary to propel us toward a common understanding and world peace, but will remain in this report many reasons), ahem..
Bluelight Reference Guide
Dissociatives The Small & Handy 3-MeO-PCMo Thread
4-[1-(3-methoxyphenyl)cyclohexyl]morpholine A study on the 2-MeO analogue: New morpholine analogues of phencyclidine: Chemical synthesis and pain perception in rats Expectations and experience reports are welcome, as always
Read full thread on Bluelight →
3-MeO-PCMo's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has 3-MeO-PCMo, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "3-MeO-PCMo (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Duration (reference)
3-MeO-PCMo: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Insufflated duration: onset 4-15m · peak 1-2h · offset 1-2h · total 3-5h · after-effects 2-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 3-MeO-PCMo? Let us know. Reports are reviewed by moderators — this is not posted publicly.