This was a truly magical experience with 3-MeO-PCE (3-Methoxy-Eticyclidine). It was beautiful enough to motivate me to write my first exhaustive trip report, so here goes nothing.
3-MeO-PCE
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Methoxieticyclidine, Methoxyieticyclidine, 3meopce
Summary
3-MeO-PCE is a potent dissociative with a significantly higher risk of inducing mania, delusions, and psychosis than other dissociatives such as ketamine or MXE. It is extremely stimulating and carries a pronounced tendency toward compulsive redosing, especially when smoked or vaporized. Due to its high potency, volumetric liquid dosing is strongly recommended.
Perspectives
“Wow this is my new favorite dissociative, out of the many many I have tried. Itβs highly euphoric, but also very deep and psychedelic. It doesnβt feel like it impairs me in any way, rather it improves my function, and doesnβt have the delusional sort of mania that 3-MeO-PCP carries.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 3-5mg | 5-10mg | 10-20mg | 20mg+ |
| Insufflated | 3-6mg | 6-12mg | 12-20mg | 20mg+ |
Light
Common
Strong
Heavy
Sources
Insufflated
Dose ladder — dose.wiki, PsychonautWikiOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 2-3 hrs | 1-2 hrs | 3-5 hrs |
| Insufflated | 3-15 min | 45-90 min | 1.5-2 hrs | 45-60 min | 3-5 hrs |
Effect Profile
11 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
6.0
Strong
6/10
Strong dissociative depth with strong mania and motor impairment, moderate insight
Dissociative Depth
×3
10
consciousness disconnection
depersonalization
derealization
physical disconnection
cognitive disconnection
visual disconnection
+6 more
Mania / Compulsion
×1
10
mania
compulsive redosing
delusions
delusions of sobriety
disinhibition
stimulation
Insight / Novel Thought
×2
6
conceptual thinking
unity and interconnectedness
creativity enhancement
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
spatial disorientation
visual disconnection
double vision
Based on reports from:
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2β4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
3d
Half tolerance
7d
Baseline
~14d
Anecdotal pattern: rapid tolerance build with consecutive-day use; partial recovery over 1β2 weeks, baseline in ~2β4 weeks. Cross-tolerance across arylcyclohexylamines is commonly reported. Data quality: anecdotal.
Cross-Tolerances
Other arylcyclohexylamines (e.g., 3-MeO-PCP, ketamine, PCP)
Effects
Aggregated from 11 single-substance Erowid experience reports; 13 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 11 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 7
8 of 11
–
7 of 11
–
6 of 11
–
4 of 11
–
4 of 11
–
3 of 11
–
3 of 11
–
Adverse Effects 5
6 of 11
–
4 of 11
–
3 of 11
–
3 of 11
–
3 of 11
–
Also reported in combinations. In the 13 3-MeO-PCE reports where another drug was taken too, 3 mention hospital, emergency services or an overdose, 1 a seizure and 4 psychosis (too few reports for percentages). In the 11 single-substance reports: 0, 0 and 3. These are not in the figures above: they cannot be put down to 3-MeO-PCE alone, and a mention is not always something that happened to the writer.
Combinations
Cross-Check 3-MeO-PCE with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 3 positive 1 neutral 4 cautionary visit
Normally I read experience reports, but this substance has only a few other reports. I am not that great of a writer, and its so hard to put my sensations into words. I love dissociates, had it not been for my love affair with opiates, I might not have ever touched another class of drug.
[Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.
The dancing electronic Terracotta Army After a few lovely past experiences with 3-MeO-PCE by myself in quiet settings I decided to go dance to some techno music on it. A somewhat well known DJ was playing a venue in my hometown and some friends and I decided to go.
In addition to the daily testosterone gel I apply, I take 10 mg aripiprazole and 100 mg lamotrigine nightly, and 150 mg bupropion in the mornings. I have experience with ketamine, 3-MeO-PCP, 3-MeO-PCE, 3-HO-PCP, 3-HO-PCE, and memantine.
I received a small sample of a relatively novel substance to try, 3-MeO-PCE, and plugged (rectal administration in a gelatin capsule). IΒm a tall, 200lb male with a very steady and calm temperament.
[Erowid Note: The doses described in this report are potentially life threatening. The amount taken is beyond a heavy dose and could pose serious health risks or result in unwanted, extreme effects. Doses such as this have been known to cause hospitalizations and/or deaths.
Earlier that night: 140mg 4-FMA (oral), speed (insufflated), GHB (oral) T- (3-5) hours: 200mg 3-MMC (oral) T+ 0 (around 7am Sunday morning): 160mg 3-MEO-PCE (oral) T+ 10min: 5mg Etizolam, 0.5mg Clonazolam (oral) T+ ?: redoses of Etizolam and Clonazolam (oral) This is a report that I'm typing for other people who have t...
Dose.wiki 1 report 1 positive visit
Wow this is my new favorite dissociative, out of the many many I have tried. Itβs highly euphoric, but also very deep and psychedelic. It doesnβt feel like it impairs me in any way, rather it improves my function, and doesnβt have the delusional sort of maniaβ¦
Bluelight Reference Guide
Dissociatives The Big & Dandy 3-MeO-PCE Thread
Also called: Methoxieticyclidine 3-MEO-PCE (the non-ketone version of Methoxetamine) is due to hit the UK next week. Thoughts? I figure this is it:
Read full thread on Bluelight β
3-MeO-PCE's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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