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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    1cP-LSD Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: 1cp, Curie, 1-cpa-lsd, 1-cyclopropanoyl-lsd, 1cplsd

    Summary dose.wiki TripSit PsychonautWiki

    1cP-LSD (1-cyclopropionyl-lysergic acid diethylamide) is an N-1 acylated prodrug that rapidly hydrolyzes to LSD in human serum, producing essentially identical pharmacology to LSD-25. Potency is approximately equivalent to LSD by weight, with most users reporting indistinguishable effects at standard doses. Use reagent testing (Ehrlich or Hofmann) on all batches to ensure authenticity and rule out NBOMe compounds or DOx substances.

    Perspectives

    “1cP-LSD now stands as one of my favorite lysergamides, second only to LSD itself. Most notable about this compound was that it was extremely visual relative to other lysergamides while remaining very lucid and coherent. There was little body load or overwhelming stimulation.”

    “Despite the limited dose this was a good experience. I felt that it was slightly stronger than 1P, with subtle but noticeable differences throughout, and there did seem to be more clarity in parts; perhaps greater control.”

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Oral 15-50Β΅g 50-100Β΅g 100-200Β΅g 200Β΅g+
    Sublingual 25-75Β΅g 75-150Β΅g 150-300Β΅g 300Β΅g+
    Light Common Strong Heavy
    Sources· 1 of 2 ladders not identified

    Oral

    Dose ladder — dose.wiki

    Sublingual

    Dose ladder — source not identified

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 0.75-2 hrs 3-5 hrs 3-5 hrs 6-24 hrs 8-10 hrs
    Sublingual 19-60 min 0.75-2 hrs 3-5 hrs 3-5 hrs 6-24 hrs 8-10 hrs

    Effect Profile

    5 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 9.2
    Intense+ 9/10

    Strong visuals, headspace, and auditory effects with moderate body load

    Visual Intensity ×3
    10
    color enhancement drifting tracers synaesthesia pattern recognition enhancement scenery slicing +4 more
    Headspace Depth ×3
    10
    conceptual thinking introspection enhancement personal meaning enhancement recursion emotion enhancement personal bias suppression +1 more
    Auditory Effects ×1
    10
    auditory enhancement music enhancement auditory distortion auditory hallucination synaesthesia
    ⚠ Body Load / Somatic Effects ×1
    6
    nausea vasoconstriction increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Empirical user reports suggest marked tolerance next day with partial recovery over 7–14 days; values are indicative and individualized. Redosing same day extends duration more than intensity.

    Cross-Tolerances

    LSD
    Psilocybin and other 5‑HT2A psychedelics

    Effects Erowid

    Aggregated from 5 single-substance Erowid experience reports; 6 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 5 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 6

    4 of 5 –
    3 of 5 –
    3 of 5 –
    3 of 5 –
    3 of 5 –
    3 of 5 –

    Adverse Effects 1

    4 of 5 –

    Also reported in combinations. In the 6 1cP-LSD reports where another drug was taken too, 1 mentions hospital, emergency services or an overdose, 0 a seizure and 0 psychosis (too few reports for percentages). In the 5 single-substance reports: 0, 0 and 0. These are not in the figures above: they cannot be put down to 1cP-LSD alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check 1cP-LSD with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 4 positive 2 neutral 2 cautionary visit
    A Fire Across the Country, a Garden of Visuals positive exp #114498

    I want to preface this report with a statement- In a country where drugs are illegal and enforcement of drug laws is largely predicated on race, doing drugs is NOT apolitical.

    nervewing · 150 ug oral / smoked
    I Felt More Grounded in the Present Moment positive exp #114623

    Boxing the Experience After the small 25ug experiment with this substance in which I made sure that the effects were felt and that they were safe I went on and had a standard trip, some 2 weeks after the LSA one, in order to allow the tolerance to reset.

    c9 · 75 ug oral
    In Which I Become a Little Amazon Indian positive exp #113721

    At 5:00 pm yesterday, I dropped 300ΞΌg of the new "Curie" analogue, 1cP-LSD. I didn't know what to expect, whether it would be similar to 1p-LSD. The comeup was gradual, taking about 1.5hrs, and I experienced no bodyload at all, no nausea or weirdness.

    rasputin1963
    Everything at Once neutral exp #114597

    Just recently decided to leave my old job after about 5 yrs and decided to celebrate by dropping a few tabs. I have done LSD prior and felt I was fairly well acquainted with the effects. Ate an early dinner then lounged around for a bit waiting till I was ready to dose.

    RxP · 100 ug oral / 200 ug oral / oral / 1 bowl smoked
    Six Times With Different People neutral exp #115381

    A Few Experiments with 1cP-LSD IΒ’ve came to report a few experiences I have had with 1cP-LSD, a rather new lysergamide, over the past year or so. In that time period, I have Β“researchedΒ” this chemical 6 times with different people.

    Pappus · 100 ug oral
    Horrible Muscle Tension on Comedown cautionary exp #113963

    So this actually happened to my gf. We were going on a psychedelic night at this club. She took quarter of one 1cp tab and I took aprox quarter of lsd gel (supposedly 400 ug, but was probably weaker).

    Filo · 25 ug oral
    Anxiety Conquered positive exp #119323

    Dosage: 150ΞΌg blotter, 2x75ΞΌg blotters 3 hours later. 300ΞΌg total. Intent: Lower my overall anxiety. Setting: Home alone during calm summer evening. I was in dark place during this time, so I set my mind to doing something with my anxiety, as I regularly experienced panic attacks and felt generally anxious.

    ModraVeverka · 150 ug sublingual / 75 ug sublingual / 75 ug sublingual
    For Depression cautionary exp #114243

    1cP-LSD for Depression (PLEASE NOTE: I was tapering off benzodiazepines with my doctor extremely slowly at the time of the experience. I was not on any type of antidepressant at the time, or one month+ prior to use.

    Misha · 100 ug buccal / smoked
    Dose.wiki 2 reports 2 positive visit
    A Fire Across the Nation 150ug sublingual positive

    Having tried it once more since this writing, 1cP-LSD now stands as one of my favorite lysergamides, second only to LSD itself. Most notable about this compound was that it was extremely visual relative to other lysergamides while remaining very lucid and…

    by nervewing
    Four Raccoons and a Squirrel 100ug sublingual, tab positive

    All in all, this was a really enjoyable and comfy, light trip. I'd definitely like to experience something similar in the future, I think the setting was an amazing choice, though sort of disappointed the first tab didn't do anything while I was canoeing. The…

    by froggie

    Bluelight Reference Guide Bluelight

    Lysergamides The Small & Handy 1cP-LSD Thread

    Starting a thread on this substance (1-cyclopropionyl-LSD), as it is available. It should be quite similar to 1p-LSD, and 1b-LSD. Anyone who has tried it, please hare your experiences here.

    Read full thread on Bluelight β†’
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 1cP-LSD, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "1cP-LSD (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Sublingualcommon ~ 112.5 Β΅g
    Dose & duration (reference)
    1cP-LSD: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Sublingual dose (Β΅g): threshold 10-20 Β· light 25-75 Β· common 75-150 Β· strong 150-300 Β· heavy 300+
    
    Sublingual duration: onset 0.32-1h Β· come-up 0.75-2h Β· peak 3-5h Β· offset 3-5h Β· total 8-10h Β· after-effects 6-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.