Zolazepam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 3 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
- 1 source
- 3 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
Summary
A substance that is structurally related to benzodiazepines. Is only used in Veterinary medicine. It is usually used in tandem with either the potent NMDA antagonist Tiletamine (at a 1:1 ratio) or with the α2 adrenergic receptor agonist Xylazine.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 1-3mg | 3-6mg | 6-12mg | 12mg+ |
| Intramuscular | 1-3mg | 3-5mg | 5-10mg | 10mg+ |
| Oral | 2.5-5mg | 5-10mg | 10-20mg | 20mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Insufflated | 5-10 min | 2-3 hrs |
| Intramuscular | 1-5 min | 2-4 hrs |
| Oral | 10-30 min | 4-6 hrs |
Tolerance
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Combinations
Cross-Check Zolazepam with another substanceHelpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Zolazepam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Zolazepam Source: SubstanceSearch (substancesearch.com) Insufflated dose (mg): light 1-3 · common 3-6 · strong 6-12 · heavy 12+ Intramuscular dose (mg): light 1-3 · common 3-5 · strong 5-10 · heavy 10+ Oral dose (mg): light 2.5-5 · common 5-10 · strong 10-20 · heavy 20+ Insufflated duration: onset 5-10m · peak 2-3h · after-effects 1-4h Intramuscular duration: onset 1-5m · peak 2-4h · after-effects 1-3h Oral duration: onset 10-30m · peak 4-6h · after-effects 1-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 4.5 mg (Insufflated).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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