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    Viloxazine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • PubChem toxicity data
    • classified Tentative

    Aliases: Emovit, Qelbree, Vivalan, Vicilan, Vivarint

    Summary dose.wiki TripSit

    Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that also modulates serotonergic activity as a 5-HT2B antagonist and 5-HT2C agonist. Originally used as an antidepressant in Europe (1974-2002), it was repurposed and FDA-approved in 2021 for ADHD treatment in the US under the brand name Qelbree. It is generally well-tolerated but may cause insomnia, irritability, somnolence, or gastrointestinal upset.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong
    Oral 50-75mg 75-150mg 150mg+
    Light Common Strong
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Comeup Peak Offset Total
    Oral 2 hrs 2-4 hrs 5 hrs 12-18 hrs 3-29 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.4
    Moderate+ 5/10

    Moderate stimulation and euphoria

    Stimulation / Energy ×3
    7
    increased energy stimulation mild stimulation
    Euphoria / Mood Lift ×2
    6
    physical euphoria cognitive euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    0

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Pill Identifiers

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    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Viloxazine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Viloxazine
    Unit
    mg
    Description
    Viloxazine
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): light 50-75 · common 75-150 · strong 150+
    
    Oral duration: onset 2h · come-up 2-4h · peak 5h · offset 12-18h · total 3-29h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 112.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.