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    Tiagabine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • PubChem toxicity data

    Aliases: Gabitril

    Summary Erowid

    Tiagabine is an anticonvulsant prescribed as an add-on drug to help control epileptic seizures. It is believed to work by enhancing the inhibitory neurotransmitter GABA. It is also prescribed off-label in the treatment of bi-polar disorder [BPD], chronic anxiety disorder, and insomnia.

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 7 single-substance Erowid experience reports

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 7 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 1

    4 of 7 –

    Adverse Effects 0

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 6 reports 3 neutral 3 cautionary visit
    Not Fun neutral exp #31573

    I was prescribed Gabitril for my anxiety. My prescription is to take up to three 4mg pills at bedtime. Well, I was bored last night and decided to take nine 4mg pills, for a total of 36mg. Let me tell you, this is not something you want to try to trip on. It's not fun.

    Twilex · Tiagabine (Gabitril) · 36 mg oral
    Too Intense for Comfort cautionary exp #29090

    Last weekend I was bored so I decided to pay my good friend 'G' a visit. Upon arriving at his house he told me he had gotten a new perscription to Gabitril, something I had never previously heard of.

    Gabitril · Tiagabine (Gabitril) · 24 mg oral
    Black Outs and Refrigerators cautionary exp #38619

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    Adam · Tiagabine (Gabitril) · 72 mg oral
    Gifts from the Pain Doctor neutral exp #39592

    My chronic pain doctor gave to me several boxes of free samples of a drug called Gabitril. Apparently, it is good against nerve related pain (pinched nerves in the spine, etc) so I said I would give it a shot. She warned me it might pack a punch though, dizziness, drowsiness, the works.

    Anonymous · Tiagabine (Gabitril) · 4.0 mg oral
    An Odd Night neutral exp #36006

    About three weeks ago, I was hanging out with my new roommate (we’ve been friends for a long time), and I was feeling too sober yet didn’t have any money for trees or alcohol, and he is prescribed many things for bipolar disorder, anxiety, depression and also adhd.

    Thrillhouse22 · Tiagabine (Gabitril) · 48 mg oral
    Totally Brain Dead cautionary exp #39040

    This happened to me not too long ago. Since I saw there weren't any reports on Tiagabine and it's dangers, I decided to submit this. Please be forewarned that this drug is not something you should even consider messing with.

    Planeteer · Tiagabine (Gabitril) · 60 mg oral

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