Alright guys, I have a little but of a 'trip report' for you. It's not much, but here goes. At 4ish AM I ingested somewhere around 1.2 grams of Propoxyphene Napsylate. Well, I had a sore throat, very, very sore, and I decided that since I didn't have class that day, I could take all that.
Propoxyphene
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki, PubChem)
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki, PubChem)
Summary
Is an analgesic in the opioid family. It is intended for mild pain and for its antitussive effects. Has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-65mg | 65-100mg | 100-200mg | 200mg+ |
Light
Common
Strong
Heavy
Sources
Oral
Dose ladder — dose.wikiOnset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 20-30 min | 1-3 hrs | 1-3 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
Falls quickly once you stop, at a rate you can't judge. After any break, treat your tolerance as gone.
No tolerance chart. Our decay curves for opioids were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
Opioid tolerance drops fast when you stop, and even a few days off can be enough, so a dose that used to be normal can now stop your breathing. Overdose deaths rise sharply after prison, detox or leaving treatment, and tolerance also falls during a hospital stay. After any break, start with a much smaller amount, try a test dose first, don't use alone, and keep naloxone within reach. Alcohol, benzodiazepines, gabapentinoids and other sedatives make an opioid overdose much more likely.
Sources: FRANK: heroin · National Harm Reduction Coalition · WHO: opioid overdose · Merrall et al. 2010 · Binswanger et al. 2007 · Strang et al. 2003 · FDA 2019: gabapentinoids and breathing
Effects
Aggregated from 7 single-substance Erowid experience reports; 6 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 7 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 3
5 of 7
–
3 of 7
–
3 of 7
–
Adverse Effects 0
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 7 reports 5 positive 1 neutral 1 cautionary visit
It's a Friday evening, normally I'd be toking on a spliff, but there is a bad batch of hash doing the rounds, so I decided to lay off it for a week. As a substitute I would probably take about 4-5 30mg codeine (neat, generic) pills, which were actually prescribed for me a couple a months ago for persistent dry cough.
I am curently experimenting with many drugs. I an a daily weed smoker, and have also tried oxycontin, XTC, Klonopin, valium, hydrocodone, cocaine, and several other drugs.
I have been experimenting with various drugs for about 13 years. Most of the drugs I have used in the past were illicit, or 'street' drugs. I have had very little experience with pharmaceuticals. A few months ago, I was prescribed Darvon for a back injury.
Ok to start I am not very experianced with drugs. I am what you would probably consider very young to be taking the drugs I do. I smoke pot occasionally, have taken DXM, all sorts of Pharms (Hydrocodone, Codiene, Oxycodone, Adderall) And was looking through my parents medicine cabinet and saw something called Propoxyph...
4:20 Ingested four darvocets, which have 100 mg of propxyphene and 325 mg of acetaminophen per pill. This is my first time experiencing with Darvocets, so I was going to start with 4 only, but figured what the hell and at 4:30 took my fifth. 5:00 no notable symptoms, really. Chatting on the internet.
I got my hands on some 65mg (Imprint 5110 V) capsules. When I pried one open I was glad to find the substance in a fine powder inside the capsule, perfect for insufflation. So I separated the powder into 3 small lines.
Pill Identifiers
4
known pill identifiers on record — view imprints, colors, shapes, and images
→
Propoxyphene's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes Propoxyphene, but its built-in data can be thinner than ours. Importing this file adds a separate "Propoxyphene (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.
⬇ Download import file
Import this file as custom substances
and you get "Propoxyphene (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer.
Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Propoxyphene? Let us know. Reports are reviewed by moderators — this is not posted publicly.