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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    NM-2-AI Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: N-methyl-2-ai

    Psychedelic Stimulant Empathogen Nootropic Research-chemical

    Summary dose.wiki TripSit PsychonautWiki

    NM-2-AI (N-methyl-2-aminoindane) is a lesser-known novel stimulant substance of the aminoindane class. It is structurally related to 2-AI and MDAI. In comparison to 2-AI, this compound has a lower potency, a longer duration and very similar effects.

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-150mg 150-200mg 200mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-60 min 30-60 min 1-2 hrs 2-3 hrs 1-3 hrs 2-4 hrs
    Insufflated 5-20 min 15-30 min 1-2 hrs 2-3 hrs 1-3 hrs 3-5 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 2.1
    Light 2/10

    Mild auditory effects with low body load and visuals

    Visual Intensity ×3
    2
    visual enhancement
    Headspace Depth ×3
    0
    Auditory Effects ×1
    4
    music enhancement
    ⚠ Body Load / Somatic Effects ×1
    3
    teeth grinding increased heart rate
    Empathogen 3.4
    Light+ 3/10

    Moderate stimulation and euphoria with mild sensory enhancement

    Empathy / Social Openness ×3
    0
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    music enhancement visual enhancement
    Stimulant 6.4
    Strong 6/10

    Strong focus with strong anxiety/jitters, moderate euphoria, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement analysis enhancement memory enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    8
    anxiety increased heart rate teeth grinding
    Based on reports from:
    PsychonautWiki NM-2-AI
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Pattern inferred from related aminoindanes and user reports rather than controlled data.

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check NM-2-AI with another substance

    NM-2-AI's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 dose.wiki 📖 PsychonautWiki 📖 TripSit
    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has NM-2-AI, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "NM-2-AI (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference) 
    NM-2-AI: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)


Insufflated duration: onset 5-20m · come-up 15-30m · peak 1-2h · offset 2-3h · total 3-5h · after-effects 1-3h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.