Nimetazepam Stats & Data
GWUSZQUVEVMBPI-UHFFFAOYSA-NReceptor Profile
Receptor Actions
Toxicity
PubChemBenzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor.
Carcinogenicity
No indication of carcinogenicity to humans (not listed by IARC).
Effect Profile
Curated + 3 ReportsStrong anxiolysis and euphoria with strong cognitive impairment, mild sedation
Tolerance & Pharmacokinetics
drugs.wikiNo tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Cross-Tolerances
Experience Report Analysis
ErowidDemographics
Gender Distribution
Too few reports for a chart: gender is known from 4 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?
- Male 3 of 4
- Female 1 of 4
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 3 experience reports (3 single-substance Erowid)
Effect Sentiment Distribution
Confidence Distribution
Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.
Too few reports for bars: these effects come from 3 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Positive Effects 1
Adverse Effects 0
Legal Status
| Country | Status | Notes |
|---|---|---|
| Hong Kong | regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance | |
| Singapore | physician prescribed drug, and is regulated under the Misuse of Drugs Act | |
| United States | categorized Schedule IV FDA and DEA |
Harm Reduction
drugs.wikiNimetazepam is marketed mainly in parts of Asia (e.g., as 5 mg 'Erimin 5'); non-medical availability often involves counterfeit tablets that may contain other benzodiazepines, making potency unpredictable—assume unknown composition and avoid mixed-source pills unless lab-checked. Next‑day sedation, impaired coordination, and memory gaps are common with long/medium-acting benzodiazepines; avoid driving or operating machinery until at least the day after use and longer if residual effects are present. Combining benzodiazepines with opioids, alcohol, GHB/GBL, or other depressants greatly increases the risk of life‑threatening respiratory depression and fatal overdose; avoid co‑use and never use alone. Tolerance develops quickly with repeated use and can encourage escalation; spacing uses by weeks and avoiding consecutive‑night dosing reduces risk of rapid tolerance. Abrupt cessation after sustained use can cause severe withdrawal (anxiety, insomnia, agitation, tremor, seizures); any taper should be slow and medically supervised. 'Blackout' amnesia can lead to unintentional redosing—pre‑measure a single dose, keep a log, and have a trusted sober person hold the supply if needed. Crushing or injecting tablets is dangerous due to insoluble binders/fillers (risk of vein damage, infection) and unpredictable kinetics; stick to oral use only. People who are pregnant can produce neonates with benzodiazepine withdrawal symptoms; discuss any exposure with a clinician. Older adults and those with renal or general frailty have heightened sensitivity to sedation and falls; lower thresholds and longer spacing are prudent. Reports note nimetazepam may partially metabolise to nitrazepam and has high oral bioavailability with relatively rapid onset—this can increase misuse potential; extra caution with redosing is warranted. In unregulated markets, prioritize drug checking where available; if not, avoid brand‑dependent assumptions (e.g., 'Erimin 5' logo) as authenticity is unreliable.
References
Data Sources
Cited References
Additional references
- Erowid Nimetazepam (Erimin) Vault — names/availability overview
- TripSit Wiki — Uncommon Benzodiazepines (nimetazepam BA, onset ≈30 min, mean half‑life 14–30 h; partial metabolism to nitrazepam)
- PubChem — Nimetazepam compound entry (identity/structure)
- EUDA (EMCDDA) European Drug Report/Overdose risk — benzodiazepines commonly present in fatal overdoses, especially with opioids
- EUDA — Risk factors (polydrug depressant use: opioids + benzodiazepines)
- DrugWise — Benzodiazepines (withdrawal dangers, driving risk, harm‑reduction advice)
- Hi‑Ground — Benzos page (unsafe combinations incl. opioids, alcohol, GHB/GBL, tramadol, ketamine; caution with antipsychotics/antihistamines)
- SubstanceSearch — Nimetazepam alias and rough timing (community HR repository)
- Bluelight — 'Happy 5' / counterfeit 'Erimin 5' discussion (counterfeit prevalence; harm‑reduction context)