Methyprylon
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- PubChem toxicity data
- classified Tentative
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- PubChem toxicity data
- classified Tentative
Aliases: Noludar
Summary
Sedative of the pipeidinedone family. Was used for treating insomnia, yet is rarely used today due to substances with fewer side effects, such as benzodiazepines.
Dose Information
| ROA | Light | Common | Strong |
|---|---|---|---|
| Oral | 150-200mg | 200-300mg | 300mg+ |
Onset, Duration & After-effects
| ROA | Peak | Total |
|---|---|---|
| Oral | 6-12 hrs | 6-12 hrs |
Tolerance
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Effects
Effect glossary — · full glossary
Combinations
Cross-Check Methyprylon with another substanceHelpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Methyprylon there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Methyprylon Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 150-200 · common 200-300 · strong 300+ Oral duration: peak 6-12h · total 6-12h · after-effects 1-16h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 250 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
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