Let me start off by saying, my drug of choice is opiates by far. Recently it has come to my attention that there is an opiod anti-diarrheal drug that is OTC and sold in most any store. This report will be short due to the nature that I have one thing to say about it, it does work.
Loperamide
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
- PubChem toxicity data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
- PubChem toxicity data
Summary
Loperamide is an opioid antidiarrheal sold under the brand name Imodium. It is also commonly used to alive symptoms of opioid withdrawal, dubbed the "Poor Man's Methadone". Loperamide cannot effectively cross the Blood Brain Barrier but when used in large enough doses or in combination with P-glycoprotein inhibitor like Quinidine, enough of the drug can cross the blood brain barrier in order to illicit central morphine-like effects.
Effects
Aggregated from 16 single-substance Erowid experience reports; 11 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 16 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 2
4 of 16
–
3 of 16
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Adverse Effects 1
3 of 16
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Also reported in combinations. In the 11 Loperamide reports where another drug was taken too, 2 mention hospital, emergency services or an overdose, 1 a seizure and 0 psychosis (too few reports for percentages). In the 16 single-substance reports: 2, 0 and 0. These are not in the figures above: they cannot be put down to Loperamide alone, and a mention is not always something that happened to the writer.
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 1 positive 2 neutral 5 cautionary visit
It's been a while since I had been without oxy. I had been using Kratom for a while, I was taking about 5-6 grams a day in capsule form. However, I had been missing that oxy feeling and I found a bunch of generic Imodium AD in my closet and remembered that someone said online it could "give you an opiate like high".
I'm sitting in the Burlington International Airport in Vermont, waiting for my delayed flight home to the Bay Area. I've just finished a weird two week vacation with my boyfriend that included a few trials with high-dose imodium.
So for some background I use to have a sizeable fentanyl habit before transitioning to Suboxone about 5 years ago. Throughout those 5 years I have tapered to my current dose of 1mg.
PRELUDE: Hello, my name is Debby and I am submitting this report because there is limited information about a drug that, in my honest opinion, is a miracle cure for opiate withdrawal/addiction. I really hope my experience can help others.
Loperamide High This is not something I would recommend to anyone to do for experimentation. There are VERY real dangers with taking too much loperamide. Intestinal blockage and rupture is a very real possibility.
Before I get into my Opiate Withdrawal dosage recommendation, I'd like to give a background, on the type of user I've been. I've been an IV opiate user, of the 'H' factor for over 5 years, with an added 4 years 'tooting' (that's how I began).
Ok, so I've been a fairly active opiate user for about 14 years now. For the last five years or so, I've been wanting to quit, simply because it's ruining my life.
Bluelight 7 threads 4 neutral 3 cautionary visit
There have been quite a few discussions over on the OD forum as to whether or not loperamide has any recreation value, or if it helps with your opiate withdrawals at all.
I have used lope up to 20-25 mg. I was always hesitant to take much more because it backs me up something fierce. I took some stool softeners (200mg) to alleviate my worries and bowels. So today I took 60mg. I'm was in the beginning of suboxone withdrawal (for the 1000th fucking time).
I ate 128 mg (64 pills) of Loperamide on Friday following the viewing of Malfunkshun's thread. My friend Rayce ate 50. It kicked in after about an hour and a half, and consisted of a tummy ache, lots of peripheral opioid symptoms (most notably the frog-in-the-throat thing) and moderate sedation.
I’ll start by saying that this case does not involve myself but a 35 year old man who was a highlighted case. I’m going to share with you his experience in taking significant amounts of Loperamide, which is known by the brand name Imodium, to kick a heroin addiction but more realistically just postpone withdrawal.
***WARNING: High dosages of loperamide are toxic to the heart and cause Long QT Syndrome, which can lead to death. Loperamide is much more dangerous than other opiates in high dosages, because unlike other opiates which are non-toxic, whose risk lies in overdosing, loperamide is quite toxic.
Disclaimer: This was stupid as fuck. I urge everyone not to repeat this. Do not mix booze and opiates, do not inject this much PG and Polysorbat 80 (Tween 80), do not take needles out of the trash can, just don't don't don't!! Had the loperamide been just a tad stronger I might've died in my sleep.
What with the recent talk about loperamide and its potential recreational use, I decided to give it a try. Although, I wasn't really counting on it to be valuable as a 'good time' drug, but more of somthing to help through withdrawals when and if they happen (I'm usually flirting with withdrawals so an easy remedy woul...
Pill Identifiers
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