It's been a long day, I've had sinus problems all day, and been somewhat zonked from a combination of not not feeling good and taking sinus medicine. Around 11:00 I had taken a Tavist-D which was making me feel pretty drained. 2:00 Mix 5 ml of GVL solution into a shot glass of water. I have never tried GHB or GVL.
GVL
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Tranquili-g, 4-pentanolide, 4-methylbutyrolactone, Gamma-methyl-gamma-butyrolactone
Summary
GVL has a density of approximately 1.05 g/mL, meaning 1 mL contains roughly 1050 mg of neat GVL. Animal studies indicate GBL is 5-7 times more potent than GVL, with human anecdotal reports aligning with typical single doses of 3-7 mL and binge totals exceeding 40 mL. Subjectively less euphoric but significantly longer-acting than GBL/GHB, with effects that plateau rather than peak sharply.
Dose Information
| ROA | Threshold |
|---|---|
| Oral | 1mL |
Only a threshold dose is documented for this substance — the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.
Sources
Oral
Dose ladder — DrugsPROOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1-3 hrs | 2-4 hrs | 3.83-8.67 hrs |
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually. With GHB and GBL, tolerance drops after you stop, so the amount you used to take can cause an overdose, and the gap between the dose you want and an overdose is small and hard to judge.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder · FRANK: GHB
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 3 reports 2 neutral 1 cautionary visit
I recently ordered several bottles of Tranquili-G, much to my disappointment. I started with the suggested dose of 1 teaspoon (1/6 ounce) with absolutely no effect after over an hour. I then took successively larger doses with no effect.
Well, a couple of days ago I posted a message to alt.drugs.ghb asking about Tranquilli-G. It arrived today; I took about 2.5mL after working from 5:30a.m til' 2:00p.m. Before I took it I was feeling agitated achy, and tired. It took about 20 min.
Bluelight 1 thread 1 cautionary visit
It's been a long day, I've had sinus problems all day, and been somewhat zonked from a combination of not not feeling good and taking sinus medicine. Around 11:00 I had taken a Tavist-D which was making me feel pretty drained. 2:00 Mix 5 ml of GVL solution into a shot glass of water. I have never tried GHB or GVL.
GVL's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track GVL there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Name
GVL
Unit
ml
Description
GVL Source: SubstanceSearch (substancesearch.com) Oral dose (ml): threshold 1mL Oral duration: onset 20-40m · come-up 0.5-1h · peak 1-3h · offset 2-4h · total 3.83-8.67h · after-effects 4-8h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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