Grayanotoxin
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
- toxicity data (PsychonautWiki)
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- no dose data
- toxicity data (PsychonautWiki)
Summary
Grayanotoxins are a group of toxic diterpenes found in the ericacaeae family of plants . More than 25 grayanotoxin isoforms have been isolated from rhododendron, though grayanotoxin I and grayanotoxin III are considered to be the most responsible for the toxic pharmacological effects of grayanotoxin-containing plants. Grayanotoxin I, as well as grayanotoxin III, act as agonists of voltage-gated sodium channels.
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
3d
Half tolerance
8d
Baseline
~14d
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
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Pharmacology, chemical data, effect profiles, and more
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