Fluetizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Fluetiz, 2'-fluorodeschloroetizolam
Summary
Fluetizolam (also called Fluetiz) is a thienotriazolodiazepine, a benzodiazepine-class depressant. It is metabolized into ฮฑ-hydroxyetizolam, an active metabolite with similar effects. It is reported to be exceptionally potent โ roughly 6โ10 times stronger than diazepam and 2โ3 times more potent than etizolam โ and this high potency increases the risks of overdose, dependency, and blackouts.
Dose Information
Dose basis. Oral: Ranges are compiled primarily from user reports due to lack of clinical dosing standards; start low and use volumetric dosing for sub-milligram accuracy. Sublingual: User reports suggest similar potency to oral with a slightly faster onset; sublingual pellets/solutions are common in the unregulated market. Doses below 1 mg require volumetric dosing to avoid fatal measurement error. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.2mg | 0.3mg | 0.5mg | 1mg |
| Sublingual | 0.2mg | 0.3mg | 0.5mg | 1mg |
Sources
Oral
Dose ladder — Drugs.WikiSublingual
Dose ladder — Drugs.WikiOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-30 min | 30 min | 3-6 hrs | 3.75-7 hrs |
| Sublingual | 15-30 min | 1-3 hrs | 3-6 hrs | 6-12 hrs |
Effect Profile
Scores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Tolerance
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines ยท Alcohol and Drug Foundation: GHB ยท FDA 2020: benzodiazepine boxed warning ยท FDA 2019: gabapentinoids and breathing ยท NHS: alcohol use disorder
Cross-Tolerances
Effects
Effect glossary — · full glossary
Combinations
Cross-Check Fluetizolam with another substanceHelpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Fluetizolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Fluetizolam Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 0.1 ยท light 0.2 ยท common 0.3 ยท strong 0.5 ยท heavy 1 Sublingual dose (mg): threshold 0.1 ยท light 0.2 ยท common 0.3 ยท strong 0.5 ยท heavy 1 Oral duration: onset 15-30m ยท peak 30m ยท offset 3-6h ยท total 3.75-7h ยท after-effects 24h Sublingual duration: onset 15-30m ยท peak 1-3h ยท offset 3-6h ยท total 6-12h ยท after-effects 24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 0.4 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Fluetizolam? Let us know. Reports are reviewed by moderators — this is not posted publicly.