I received some fluclotizolam blotters and was extremely excited to try this new chemical out as I had not even tried a benzo in almost a entire year. I have vast experience with many different benzodiazipines and I was very curious how this one would rank next to etizolam.
Fluclotizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- classified Tentative
- classified Research-chemical
Summary
Fluclotizolam is a thienotriazolodiazepine, a benzodiazepine-class depressant that first appeared as a designer drug in 2017 despite having been first synthesized in 1979 and never marketed. It is potent, estimated at roughly 3 times stronger than etizolam, and has a comparatively short half-life that can lead to pronounced rebound insomnia and anxiety. Without medical oversight it poses serious overdose and dependence risks, particularly when combined with other depressants.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual | 250ug | 250-500ug | 500-750ug | 750ug+ |
Light
Common
Strong
Heavy
Sources
Oral / Sublingual
Dose ladder — TripSitOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral / Sublingual | 10-30 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
| Insufflated | 5-15 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
| Rectal | 10-30 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
Effect Profile
1 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
8.0
Intense
8/10
Strong anxiolysis and euphoria with mild sedation and cognitive impairment
Anxiolysis
×3
10
anxiolysis
anxiety suppression
anxiolytic
muscle relaxation
emotion suppression
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
4
amnesia
delusions of sobriety
Euphoria / Mood Lift
×1
10
cognitive euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Cross-Tolerances
all benzodiazepines
z-drugs
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
Combinations
Cross-Check Fluclotizolam with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 1 report 1 cautionary visit
Fluclotizolam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Fluclotizolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Name
Fluclotizolam
Unit
mg
Description
Fluclotizolam Source: SubstanceSearch (substancesearch.com) Oral / Sublingual dose (mg): threshold 0.05 · light 250ug · common 250-500ug · strong 500-750ug · heavy 750ug+ Oral / Sublingual duration: onset 10-30m · peak 1-3h · offset 2-4h · total 3-6h · after-effects 1-36h Insufflated duration: onset 5-15m · peak 1-3h · offset 2-4h · total 3-6h · after-effects 1-36h Rectal duration: onset 10-30m · peak 1-3h · offset 2-4h · total 3-6h · after-effects 1-36h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 0.38 mg (Oral / Sublingual).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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