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    Disclaimer
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    โš  Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Etizolam Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 27 combo interactions documented
    • toxicity data (PsychonautWiki, PubChem)
    • classified Research-chemical

    Aliases: Etiz, Towa, Zoly, Depas, Lamet, etizest, etilaam, sedekopan, etizola, inxity

    Summary dose.wiki Erowid TripSit PsychonautWiki

    Etizolam (also known as Etilaam, Etizest, Depas, and many others) is a novel depressant substance of the thienodiazepine class. Etizolam is chemically related to benzodiazepines and acts by binding to GABA receptors in the brain. Etizolam is not commonly prescribed.

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-2mg 2-4mg 4mg+
    Sublingual 0.5-1mg 1-2mg 2-5mg 5mg+
    Light Common Strong Heavy
    Sources· 1 of 2 ladders not fully identified

    Oral

    Dose ladder — dose.wiki, TripSit

    Sublingual

    Dose ladder — Light: same as the Oral row (dose.wiki, PsychonautWiki, TripSit) · Common: same as the Oral row (dose.wiki, PsychonautWiki, TripSit) · Strong, Heavy: not identified

    Benzo Equivalence Calculator

    mg
    1.0 mg Etizolam
    =
    โ€” mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-30 min 30-60 min 2-3 hrs 1.5-2.5 hrs 6-24 hrs 5-8 hrs
    Sublingual 10-20 min 20-45 min 2-3 hrs 1.5-2.5 hrs 6-24 hrs 5-8 hrs

    Effect Profile

    75 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 60 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 8.3
    Intense 8/10

    Strong anxiolysis, euphoria, and sedation with strong cognitive impairment

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant emotion suppression
    Sedation / Relaxation ×2
    9
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    10
    motor control loss memory suppression amnesia delusions of sobriety
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria physical euphoria disinhibition

    Tolerance

    Build-up develops over 1โ€“4 weeks of daily use (thienodiazepine with full benzodiazepine cross-tolerance)
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines ยท Alcohol and Drug Foundation: GHB ยท FDA 2020: benzodiazepine boxed warning ยท FDA 2019: gabapentinoids and breathing ยท NHS: alcohol use disorder

    Cross-Tolerances

    Benzodiazepines
    Other thienodiazepines

    Effects Erowid Bluelight

    Aggregated from 60 single-substance Erowid and 15 Bluelight experience reports; 68 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Rows resting on fewer than 20 reports show a count (“3 of 7”) instead of a bar. Why 20?

    Positive Effects 20

    38.7% (95% interval 28 to 50 percent) 85%
    36.0% (95% interval 26 to 47 percent) 89%
    26.6% (95% interval 18 to 38 percent) 83%
    13.3% (95% interval 7 to 23 percent) 92%
    8.0% (95% interval 4 to 16 percent) 85%
    6.7% (95% interval 3 to 15 percent) 82%
    7 of 15 81%
    5 of 15 82%
    2 of 15 82%
    2 of 15 88%
    2 of 15 88%
    1 of 15 85%
    1 of 15 80%
    1 of 15 90%
    1 of 15 85%
    1 of 15 80%
    1 of 15 85%
    1 of 15 85%
    1 of 15 85%
    1 of 15 80%

    Adverse Effects 34

    26.6% (95% interval 18 to 38 percent) 87%
    12.0% (95% interval 6 to 21 percent) 82%
    10.7% (95% interval 6 to 20 percent) 85%
    6.7% (95% interval 3 to 16 percent) –
    5.0% (95% interval 2 to 14 percent) –
    4 of 15 82%
    4 of 15 89%
    2 of 15 85%
    2 of 15 90%
    2 of 15 85%
    1 of 15 85%
    1 of 15 75%
    1 of 15 80%
    1 of 15 80%
    1 of 15 85%
    1 of 15 85%
    1 of 15 90%
    1 of 15 85%
    1 of 15 80%
    1 of 15 75%
    Show 14 more adverse effects
    1 of 15 80%
    1 of 15 85%
    1 of 15 75%
    1 of 15 85%
    1 of 15 90%
    1 of 15 90%
    1 of 15 90%
    1 of 15 85%
    1 of 15 90%
    1 of 15 85%
    1 of 15 85%
    1 of 15 90%
    1 of 15 80%
    1 of 15 85%

    Also reported in combinations. In the 68 Etizolam reports where another drug was taken too, 7 (10.3%) mention hospital, emergency services or an overdose, 1 (1.5%) a seizure and 3 (4.4%) psychosis. In the 60 single-substance reports: 3.3%, 3.3% and 0.0%. These are not in the figures above: they cannot be put down to Etizolam alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check Etizolam with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Love-hate Relationship With This Love of Mine neutral exp #104533

    I've been taking etizolam for a while now, ever since a 'business' acquaintance of mine introduced it to me and got me in with a sorta secret online vendor selling his (or her) own press Etiz pills. Although Etizolam isn't 'controlled' here in the UK, you still need someone to supply it to you.

    OrganicJunkie · oral
    Liquid Bliss positive exp #99204

    To start off, Iย’ve had very in depth experience with virtually every drug from DMT to opiates. Iย’ve also gone through moderate-heavy use of benzodiazepines, and the dosage that I take is not recommended. Iย’ve had chronic insomnia and anxiety for years, so the use of Etizolam for these will be addressed as well.

    WavesOfEuphoria
    Quiet Night in to Test the Waters neutral exp #114528

    I am a 24 year old male, 186cm and 92kg, A is a 24 year old female, ~165cm and 60kg. I wanted to acquire some etizolam for a while, and finally found a vendor that had excellent reviews.

    Etiztest · 670 ug sublingual
    My New Perspective cautionary exp #109633

    I wrote a previous report about being an addict to RC benzo drugs for a year. I pretty well got my ass kicked by these legal benzo drugs, which I was thoroughly and wantonly abusing. I was feeling pretty emotional when I wrote it . I feel much better now, and I have a new perspective.

    Jonnyboy369
    A Novel Adventure positive exp #108726

    Drank 2 strong beers (6% ABV) around 10 pm during a movie with my girlfriend. This in no way affected the intoxication I experienced on this compound, but was noted in case the lingering effects of ethanol contributed to the subsequent 'black-out' that I experienced.

    Dr._Psychonaut · 2 glasses oral / 2 mg oral / 1.2 mg oral
    Holy Hell That Potency neutral exp #108403

    1mg Etizolam - kind of like valium and ambien I hadn't done much research on Etizolam, but had heard MANY people talking about it for a while, and wanted to see what the buzz was all about.

    MrMoran · 1 mg oral
    Great Weapon in My Anxiety Reducing Arsenal cautionary exp #109353

    An Excellent Benzo Substitute I'm somebody who has dealt with both generalised and social anxiety for the last several years, to varying degrees of intensity. Prior to eventually visiting a doctor regarding my ailments and getting proper help, I was pretty much learning with ways to cope with my anxiety symptoms on my...

    Articuno
    Stronger Than You'd Think positive exp #103068

    My friend Sandy (not her real name) and I had both developed quite a heavy benzodiazepine habit. We had both been used to taking about 8mg of Alprazolam each, every day through our school semester.

    peggyolson · 2 mg oral / 3 mg oral / 1 mg oral
    Bluelight 4 threads 3 neutral 1 cautionary visit
    Etizolam Experienced Notes One Month Use cautionary

    It has been quite a while since I have felt the need to post a TR, but a recent one month binge with etizolam has produced some results I found interesting and feel compelled to share.

    Etizolam 20 Mg Inexperienced My 3 Weeks With Etizolam neutral

    Hello, This is my first trip report so please excuse me if I seem to ramble or whatnot. I originally did not want to make this thread but a friend has talked me into it. First, let me give you a little background information. I am a 20 year old male in Eastern United States.

    20 mg mentioned in the thread; auto-extracted, unverified
    Etizolam 5mg My Experience neutral

    First of all this is the first benzo I have tried (I know it's not actually a benzo). I did this last night and wrote my experience throughout the duration. 15:05 - Swallowed 1mg of Etizolam 16:00 - Tiniest bit stumbly, no noticable other effects, may take another 1mg.

    5 mg mentioned in the thread; auto-extracted, unverified
    Etizolam Iv Experience neutral

    Im 25 weigh 165 I have a moderate tolerance for benzos. I consider them a tool type a drug , used for spacific purposes(come-downs,panic attacks,sleep,alcohol w/d,ect.) But when i got some etizolam powder and converted it to liquid(PG). This was a whole different animal than the tablets, this was different.

    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Etizolam, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "Etizolam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Sublingualcommon ~ 1.5 mg
    Dose & duration (reference)
    Etizolam: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Sublingual dose (mg): threshold 0.25 ยท light 0.5-1 ยท common 1-2 ยท strong 2-5 ยท heavy 5+
    
    Sublingual duration: onset 10-20m ยท come-up 20-45m ยท peak 2-3h ยท offset 1.5-2.5h ยท total 5-8h ยท after-effects 6-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.