Efavirenz
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- partial dose data
- duration data present
- 28 combo interactions documented
- toxicity data (PsychonautWiki, PubChem)
- 1 source
- partial dose data
- duration data present
- 28 combo interactions documented
- toxicity data (PsychonautWiki, PubChem)
Aliases: Sustiva
Summary
Efavirenz (sold by the brand name Sustiva) is an antiretroviral medication used in the treatment and prevention of HIV/AIDS. It is notable for being able to produce psychedelic and hallucinogenic effects despite possessing an extremely novel pharmacological profile and chemical structure not shared with any other psychedelic substance.
Dose Information
| ROA | Common |
|---|---|
| Smoked BA 50% | 600-1800mg |
Sources
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Smoked | 1-5 min | 1-2 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 1 other substance of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals with mild headspace, auditory effects, and body load
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Effect glossary — · full glossary
Combinations
Cross-Check Efavirenz with another substancePill Identifiers
Helpful Links
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