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    DOx Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 28 combo interactions documented
    • toxicity data (PsychonautWiki, PubChem)

    Summary PsychonautWiki

    Substituted dimethoxyamphetamines (also known as DOx) refers to a class of psychedelic amphetamines originally synthesized and documented by Alexander Shulgin in his investigation of psychoactive phenethylamines in the 1970s. Shulgin later published his findings along with other mescaline-derived compounds in his semi-autobiographical book/organic synthesis reference PiHKAL ("Phenethylamines I Have Known and Loved").

    Effect Profile

    class estimate

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 1 other substance of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.5
    Strong 6/10

    Strong visuals with mild headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    color enhancement drifting tracers pattern recognition enhancement visual distortions brightened colour
    Headspace Depth ×3
    4
    introspection time distortion confusion
    Auditory Effects ×1
    4
    auditory distortion
    ⚠ Body Load / Somatic Effects ×1
    4
    nausea increased heart rate
    Based on reports from:

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Neutral

    Combinations

    Cross-Check DOx with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Bluelight 4 threads 4 neutral visit
    Dox Inexperienced This One Is Funny neutral

    this trip was i bealeve my 8th or nineth time to take blotter unknown dox compound - date summer 07 it all starts again over at my friends apartment, i went over there after work like always.

    Dox Inexperienced The On Off Switch neutral

    Now i say DOx because i am absolutely certain it was not LSD, and what i experienced has the most similarities too a DOx compound, possibly DOB. This would of been the second time on these specific tabs, so my second time on DOx.

    Dox First Time Clouded Clarity neutral

    Picked up: two, white, unperf. blotter, suspected DOx compound Age: 21 Weight: 150 I believe this is my first trip report so i'll make it a good one. I've been involved in a loving relationship with psychdelics, mainly mushrooms for about 4 years now, taking mushrooms especially about 50 times in the that period.

    Dox Or 25x Nbome 1 Tab Familiar What Is It Its So Good neutral

    I keep skimming around the net and it sucks that if I had any Marquis liquid left I would simply give it a test, but I am inclined to believe this couple blotters I picked up is DOB/DOI or 25B-NBOMe/25I-NBOMe. Certainly convinced.

    1 tab mentioned in the thread; auto-extracted, unverified
    →

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