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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    DOM Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Stp, Tranquility, Serenity, tranquility, and peace

    Summary dose.wiki Erowid TripSit PsychonautWiki

    2,5-Dimethoxy-4-methylamphetamine (also known as DOM and STP or "Serenity, Tranquility and Peace") is a lesser-known psychedelic substance of the amphetamine class. DOM is a member of the DOx family of compounds which are known for their high potency, long duration, and mixture of psychedelic and stimulant effects. It produces its effects by acting on serotonin receptors in the brain.

    Perspectives

    “Serenity, Tranquility, Peace, is certainly a fitting nickname for this substance. This is absolutely one of the most gentle psychedelics I have tasted, save for some bumpiness on the comeup.”

    “There is almost certainly an effect. Physically there is a slight dryness in the mouth, and my eyes are noticeably dilated. There is an eerie feeling overall.”

    “I suspect that for anyone who doesn't encounter these issues there is much of interest to explore. Unfortunately though, this one just doesn't seem to be for me.”

    Dose Information dose.wiki Drugs.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 1-2.5mg 2.5-5mg 5-7.5mg 7.5mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, Drugs.Wiki, TripSit

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 1-2 hrs 2-3 hrs 6-8 hrs 3-5 hrs 4-16 hrs 12-16 hrs

    Effect Profile

    42 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 29 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 7.0
    Strong+ 7/10

    Strong visuals and auditory effects with strong body load, moderate headspace

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement pattern recognition enhancement visual distortions
    Headspace Depth ×3
    6
    conceptual thinking thought connectivity time distortion
    Auditory Effects ×1
    8
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction increased heart rate
    Stimulant 6.5
    Strong 6/10

    Strong stimulation with strong anxiety/jitters, moderate euphoria, mild focus

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria
    Focus / Productivity ×2
    4
    analysis enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate vasoconstriction

    Tolerance

    Build-up develops rapidly; very long duration provides natural spacing
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Acute tolerance rises rapidly after a single dose and can persist for days; functional tolerance commonly makes redosing ineffective and mostly prolongs duration. Cross-tolerance with other classic serotonergic psychedelics is expected. Data are primarily from community reports and general psychedelic pharmacology rather than controlled trials.

    Cross-Tolerances

    LSD
    Mescaline/2C-x

    Effects Erowid Bluelight

    Aggregated from 29 single-substance Erowid and 13 Bluelight experience reports; 25 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Rows resting on fewer than 20 reports show a count (“3 of 7”) instead of a bar. Why 20?

    Positive Effects 37

    64.3% (95% interval 49 to 77 percent) 83%
    64.3% (95% interval 49 to 77 percent) 78%
    52.4% (95% interval 38 to 67 percent) 85%
    45.3% (95% interval 31 to 60 percent) 87%
    40.5% (95% interval 27 to 56 percent) 85%
    30.9% (95% interval 19 to 46 percent) 80%
    23.8% (95% interval 14 to 38 percent) 82%
    19.0% (95% interval 10 to 33 percent) 83%
    19.0% (95% interval 10 to 33 percent) 85%
    16.6% (95% interval 8 to 31 percent) 90%
    10.3% (95% interval 4 to 26 percent) –
    4 of 13 85%
    2 of 13 85%
    2 of 13 85%
    2 of 13 92%
    1 of 13 80%
    1 of 13 85%
    1 of 13 75%
    1 of 13 90%
    1 of 13 80%
    Show 17 more positive effects
    1 of 13 85%
    1 of 13 85%
    1 of 13 85%
    1 of 13 95%
    1 of 13 85%
    1 of 13 85%
    1 of 13 80%
    1 of 13 80%
    1 of 13 80%
    1 of 13 75%
    1 of 13 75%
    1 of 13 75%
    1 of 13 70%
    1 of 13 75%
    1 of 13 75%
    1 of 13 85%
    1 of 13 85%

    Adverse Effects 39

    52.4% (95% interval 38 to 67 percent) 84%
    28.6% (95% interval 17 to 44 percent) 85%
    11.9% (95% interval 5 to 25 percent) 80%
    11.9% (95% interval 5 to 25 percent) 75%
    10.3% (95% interval 4 to 26 percent) –
    10.3% (95% interval 4 to 26 percent) –
    5 of 13 88%
    5 of 13 79%
    4 of 13 80%
    3 of 13 85%
    3 of 13 83%
    3 of 13 85%
    3 of 13 78%
    3 of 13 82%
    3 of 13 82%
    2 of 13 85%
    1 of 13 85%
    1 of 13 80%
    1 of 13 75%
    1 of 13 80%
    Show 19 more adverse effects
    1 of 13 75%
    1 of 13 85%
    1 of 13 75%
    1 of 13 75%
    1 of 13 85%
    1 of 13 85%
    1 of 13 80%
    1 of 13 85%
    1 of 13 85%
    1 of 13 80%
    1 of 13 80%
    1 of 13 80%
    1 of 13 80%
    1 of 13 85%
    1 of 13 75%
    1 of 13 70%
    1 of 13 80%
    1 of 13 85%
    1 of 13 90%

    Also reported in combinations. In the 25 DOM reports where another drug was taken too, 1 (4.0%) mentions hospital, emergency services or an overdose, 0 (0.0%) a seizure and 2 (8.0%) psychosis. In the 29 single-substance reports: 6.9%, 0.0% and 3.4%. These are not in the figures above: they cannot be put down to DOM alone, and a mention is not always something that happened to the writer.

    Combinations

    Cross-Check DOM with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 4 positive 2 neutral 2 cautionary visit
    Prophetic Dream positive exp #60370

    This weekend has been the culmination of a wonderful month. A series of really great events in my life coupled with some important realizations have led me to being able to continually maintain a flow of love radiating from myself, which has spread to others around me and which has made me the happiest I've ever been f...

    Xorkoth · 7.0 mg oral
    The Bliss of the Sun positive exp #110997

    T0:00- I woke up feeling a bit odd from a dissociative binge the day before, a roiling combination of PCP, 3-MeO-PCP and 3-MeO-PCE, consolation for a failed political action earlier in the day. This has mostly worn off by the time we dose though. We decide weΒ’re all going to go out on an adventure.

    nervewing
    My Day With STP neutral exp #107437

    5/10/13 Dose: 4mg DOM Taken at 8:30am. Fell asleep at 3:00am the next morning. Duration.....14-18hr. My Day With STP After my iboga experience I was invited to California to continue on my journey. The trip out West really congealed the insights, visions, and love from my ibogaine treatment into the person I am now.

    Morninggloryseed · 4 mg oral
    Set The Controls for the Heart of the Man positive exp #3216

    I had been fairly certain ever since I got to Burning Man that I would save the DOM for the night of the Burn. My one past experience with DOM was at a dosage level that was slightly too low (7 mg), but I could see that it was a drug of the absolute highest quality, in the same class as LSD, mushrooms, etc.

    77k · 11.3 mg oral / 3.0 g oral / smoked / inhaled
    Fear is the Mind Killer positive exp #67976

    A little background on my tripping experience...I have shroomed twice, tripped on LSA twice, and ate at least a sheets worth of 'acid' (that is, blotter that is said to be LSD) in about 5 months from September 2006-February 2007.

    Joker · insufflated / insufflated
    Everything That Begins Bad Ends Good neutral exp #90371

    Back in November, I began looking into the use of LSD. I had tried cannabis, mdma, oxycodone, hydrocodone, codeine, morphine, opium, amphetamine, methylphenidate and dex methyl, ketamine, methamphetamine, coke, xanax, ativan and a few more.

    dmtoligy
    Accidental Overdose cautionary exp #81707

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    4thDimension · 30 mg oral / 4 mg oral / 6 mg oral
    Trapped Inside My Own Mind cautionary exp #102614

    I had it decided. I was going to take 15mg of DOM. I had taken this dosage before but with tolerance of only a few days and again the day after. I tripped but it was nowhere near this experience.

    Logulm · 15 mg oral / repeated smoked / repeated smoked
    Bluelight 8 threads 3 positive 3 neutral 2 cautionary visit
    Dom First Time Prophetic Dream positive

    This weekend has been the culmination of a wonderful month. A series of really great events in my life coupled with some important realizations have led me to being able to continually maintain a flow of love radiating from myself, which has spread to others around me and which has made me the happiest I've ever been f...

    Dom 6 5mg First Time Zoomy And Stupifying positive

    Some Backstory The day before I had taken some LSD. It must have been around 200ug, but it turned out to be one of the most amazing trips I've had in some time. It was a spur of the moment trip and turned out to be a really healing experience. Soul cleansing all the way.

    Dom 4mg First Time My Day With The Infamous Stp neutral

    5/10/13 Dose: 4mg DOM Taken at 8:30am. Fell asleep at 3:00am the next morning. Duration.....14-18hr. My Day With STP After iboga I was invited to California to continue on my journey. The trip out West really congealed the insights, visions, and love from my iboga experience into the person I am now.

    4 mg mentioned in the thread; auto-extracted, unverified
    Dom 5mgs First Time The Spirits Of Light And Dark positive

    "The Spirit of Light and Dark (A Report on DOM) Spring 2007" I recently had the privilege of trying a rare, illegal compound that I acquired through a trusted buddy of mine whom I have known for quite some time now.

    5 mg mentioned in the thread; auto-extracted, unverified
    Dom Experienced A Holy War In My Head cautionary

    I recently experienced an excessively strong DOM trip, and I'd like to contribute to the numerous exhortations to start off with low doses when trying any DOx chemical.

    Dom Stp 5mg First Time Was Expecting Better cautionary

    Hey bluelighters! This is my first trip report ever so forgive me if it's not clear enough or my english is not good. I'm a male, 17 years old, about 75Kg. I've done MDMA (11 times), DOC (8 times), Paroxetine, Alprazolam, Diazepam and Delorazepam in the last six months.

    5 mg mentioned in the thread; auto-extracted, unverified
    7 5mg Dom First Time A Trip Report neutral

    I'm just now reaching the very end of my DOM trip and boy was it a far out journey. For the first few hours, I just felt more of a speedy, anxious anticipation as I could feel my energy rise, but not hallucinatory effects. I wanted to move and I felt extremely energised even though I was a bit sluggish before.

    Dom 15mg Experienced Meeting The Smurf People neutral

    DOM is one hell of a drug. I have experience with LSA, LSD, shrooms, Fly Agaric, DXM, Ketamine, DMT, 25B NBOMe, mescaline and DOM. Out of all of those I must say DOM has settled in my heart as something very special to me though I do not actually know what.

    15 mg mentioned in the thread; auto-extracted, unverified
    Dose.wiki 1 report 1 positive visit
    The Bliss of Summer 10 mg sublingual positive

    Serenity, Tranquility, Peace, is certainly a fitting nickname for this substance. This is absolutely one of the most gentle psychedelics I have tasted, save for some bumpiness on the come up. It’s a calm, peaceful, and harmonious experience that made me feel…

    by nervewing

    Bluelight Reference Guide Bluelight

    Phenethylamines The Big & Dandy DOM Thread

    External Information Links: Erowid DOM Vault (experience reports) PIHKAL Entry for DOM Wikipedia entry DOX Safety Discussion Thread Original post: there is not much to find about the dosing DOM/STP. any suggestions? Shulgin writes 3-10 mg. But there are first time reports with much higher dosage. irresponsible?

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #68: DOM

    “There is almost certainly an effect. Physically there is a slight dryness in the mouth, and my eyes are noticeably dilated. There is an eerie feeling overall.”

    β€” Alexander Shulgin, PiHKAL (with 1.0 mg)
    →

    Helpful Links

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes DOM, but its built-in data can be thinner than ours. Importing this file adds a separate "DOM (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "DOM (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.