Deschloroetizolam is not worth buying or trying. Long time Psychonaut, pharm-enthusiast; benzo lover; eitozolam user. I bought Deschloroetizolam doing little research and basically just read the hype. I finally tried it this week in varying doses.
Deschloroetizolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 27 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Etizolam-2
Summary
Deschloroetizolam is a short-acting psychoactive substance of the thienodiazepine class which has been shown to produce depressant, anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant and amnesic effects. Deschloroetizolam, like benzodiazepines, binds to modulatory sites on the GABA receptors. Deschloroetizolam is closely related to etizolam (Etilaam), triazolam (Halcion), and alprazolam (Xanax).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 2-4mg | 4-6mg | 6-12mg | 12mg+ |
Light
Common
Strong
Heavy
Sources
Oral
Dose ladder — dose.wiki, PsychonautWiki, TripSitOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-60 min | 3-4 hrs | 3-4 hrs | 8-10 hrs |
Effect Profile
3 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
8.0
Intense
8/10
Strong anxiolysis and euphoria with mild sedation and cognitive impairment
Anxiolysis
×3
10
anxiety suppression
anxiolytic
muscle relaxation
muscle relaxant
emotion suppression
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
4
amnesia
delusions of sobriety
Euphoria / Mood Lift
×1
10
cognitive euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.
No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.
How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.
Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder
Cross-Tolerances
Benzodiazepines
Z-drugs (zolpidem, zopiclone, etc.)
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
Combinations
Cross-Check Deschloroetizolam with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 3 reports 3 neutral visit
Deschloroetizolam 1st Time I have long and extensive experience with benzos, prescription ones and also from the research chemicals category, such as deschloroetizolam. I had a hard day and sleepless night before yesterday and not only my usual Xanax or pyrazolam were helping.
History: No benzo tolerance. I usually use them for around 6 months on and then 6 months off. I suffer from social anxiety and depression. Tablets were small 5mg hot pink coloured. Very pleasurable headspace starts about 45 minutes after ingesting 5mg.
Deschloroetizolam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes Deschloroetizolam, but its built-in data can be thinner than ours. Importing this file adds a separate "Deschloroetizolam (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.
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Ranges are harm-reduction guidance, not a prescription.
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