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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Delorazepam Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 3 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 27 combo interactions documented
    • PubChem toxicity data

    Aliases: En, Dadumir, Nordiclazepam, Chlordesmethyldiazepam

    Summary dose.wiki TripSit DrugBank

    Delorazepam is a benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal muscle relaxant, hypnotic and anticonvulsant properties. It may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment.

    Dose Information source varies by band

    ROA Light Common Strong Heavy
    Oral 0.25-0.5mg 0.5-1.5mg 1.5-2mg 2-3mg+
    Sublingual 0.25-0.5mg 0.5-1.5mg 1.5-2mg 2-3mg+
    Light Common Strong Heavy
    Sources· 2 of 2 ladders not fully identified

    Oral

    Dose ladder — Light–Strong: dose.wiki, TripSit · Heavy: not identified

    Sublingual

    Dose ladder — Light–Strong: same as the Oral row (dose.wiki, TripSit) · Heavy: not identified

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-90 min 0.5-2 hrs 2-6 hrs 6-18 hrs 72 hrs 12-27.5 hrs
    Sublingual 30-90 min 30-90 min 2-6 hrs 6-18 hrs 72 hrs 12-27 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.1
    Strong+ 7/10

    Strong anxiolysis and euphoria with strong cognitive impairment, mild sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant emotion suppression
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    10
    motor control loss memory suppression amnesia delusions of sobriety double vision
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria physical euphoria disinhibition

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Effects dose.wiki TripSit

    Positive
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check Delorazepam with another substance

    →

    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Delorazepam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Delorazepam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Delorazepam
    Unit
    mg
    Description
    Delorazepam
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): light 0.25-0.5 · common 0.5-1.5 · strong 1.5-2 · heavy 2-3+
    Sublingual dose (mg): threshold 0.125 · light 0.25-0.5 · common 0.5-1.5 · strong 1.5-2 · heavy 2-3+
    
    Oral duration: onset 0.5-1.5h · come-up 0.5-2h · peak 2-6h · offset 6-18h · total 12-27.5h · after-effects 72h
    Sublingual duration: onset 0.5-1.5h · come-up 0.5-1.5h · peak 2-6h · offset 6-18h · total 12-27h · after-effects 72h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 1 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.