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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Buphedrone Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • partial dose data
    • duration data present
    • 29 combo interactions documented
    • classified Research-chemical

    Stimulant Research-chemical

    Summary TripSit

    A cathinone stimulant first discovered in 1928, has gained some modest popularity as a mephedrone replacement. Said to be to be around 2-3x more potent than methcathinone.

    Dose Information source varies by band

    ROA Light Common Heavy
    Oral 10-30mg 30-50mg 50-80mg+
    Light Common Heavy
    Sources· 1 of 1 ladders not fully identified

    Oral

    Dose ladder — Light, Common: dose.wiki, TripSit · Heavy: not identified

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 10-20 min 2-3 hrs 1-8 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 3.8
    Moderate 4/10

    Strong euphoria with strong anxiety/jitters, mild stimulation

    Stimulation / Energy ×3
    4
    stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    9
    physical euphoria cognitive euphoria euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    View methodology →

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check Buphedrone with another substance

    Buphedrone's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Buphedrone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Buphedrone
    Unit
    mg
    Description 
    Buphedrone
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 10-30 · common 30-50 · heavy 50-80+

Oral duration: onset 10-20m · peak 2-3h · after-effects 1-8h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 40 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.