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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Brotizolam Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 27 combo interactions documented
    • PubChem toxicity data

    Aliases: Dormex, Noxtal, We-941, Lendorm, Goodmin, lendormin

    Summary dose.wiki TripSit

    Brotizolam is an extremely potent short-acting thienotriazolodiazepine prescribed for short-term treatment (2-4 weeks only) of severe insomnia. Doses are active at as little as 80 micrograms, with therapeutic doses typically 0.125-0.25 mg. Residual effects the next day may impair cognitive and motor function, particularly above 0.5 mg.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Oral 100ug-200ug 200-400ug 400ug-600ug 600ug+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Benzo Equivalence Calculator

    mg
    0.25 mg Brotizolam
    =
    — mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-30 min 30-45 min 1-2 hrs 4-6 hrs 12 hrs 5.75-9.25 hrs

    Effect Profile

    1 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.3
    Strong+ 7/10

    Strong anxiolysis and euphoria with strong cognitive impairment, mild sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant emotion suppression
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    9
    motor control loss cognitive impairment amnesia delusions of sobriety
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria physical euphoria disinhibition
    Based on reports from:

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Cross-Tolerances

    Other benzodiazepines
    Z-drugs

    Effects dose.wiki TripSit

    Positive
    Negative
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check Brotizolam with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 1 report 1 neutral visit
    Not Really Sure neutral exp #96597

    I've been stuck in Israel for a year now, no friends, some have just stopped talking to me from Boston, where I grew up. I'll be back in a week though after I finish this art contest shit...

    Ragey · 0.75 mg oral
    Bluelight 1 thread 1 neutral visit
    Brotizolam neutral

    i have some 0.250(=10mg diazepam) brotizolam ''Bondormin'' pills, i want to hear any opinions wrom who been experienced this benzo. i know its banned in canada & maybe in the US too...

    →

    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Brotizolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Brotizolam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Brotizolam
    Unit
    µg
    Description
    Brotizolam
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (µg): threshold 80ug · light 100ug-200ug · common 200-400ug · strong 400ug-600ug · heavy 600ug+
    
    Oral duration: onset 15-30m · come-up 30-45m · peak 1-2h · offset 4-6h · total 5.75-9.25h · after-effects 12h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 300 µg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.