Alpha-GPC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
Aliases: Alfa-gpc, Choline alfoscerate, L-alpha glycerylphosphorylcholine
Summary
Alpha-GPC is legal as a dietary supplement in the US and Canada but is a prescription medication in some European countries. A 2021 study found increased stroke risk with long-term use (10+ years), so extended daily use may warrant caution. Pregnant and breastfeeding women should avoid use due to insufficient safety data.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-300mg | 300-500mg | 500-1000mg | 1000mg+ |
Sources
Oral
Dose ladder — dose.wiki, PsychonautWikiOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 45-75 min | 1-2 hrs | 2-4 hrs | 3.75-7.25 hrs |
Tolerance
Effects
Effect glossary — · full glossary
Helpful Links
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes Alpha-GPC, but its built-in data can be thinner than ours. Importing this file adds a separate "Alpha-GPC (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Alpha-GPC? Let us know. Reports are reviewed by moderators — this is not posted publicly.