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    Disclaimer
    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Adinazolam Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 27 combo interactions documented
    • classified Tentative

    Aliases: Deracyn, U-41,123, Adinazolamum

    Depressant Benzodiazepine

    Summary dose.wiki TripSit

    Adinazolam is a short-acting triazolobenzodiazepine originally investigated as both an anxiolytic and antidepressant but never FDA approved. In clinical trials (10-90 mg/day) it showed rapid relief of anxiety and modest antidepressant efficacy comparable to tricyclics with fewer anticholinergic effects. Human studies found adinazolam causes the most mental and physical sedation compared to diazepam and lorazepam, along with significant mental unpleasantness.

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Oral 5-15mg 15-30mg 30-50mg 50mg+
    Sublingual 5-15mg 15-30mg 30-50mg 50mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, Drugs.Wiki, TripSit

    Sublingual

    Dose ladder — Light–Heavy: same as the Oral row (dose.wiki, Drugs.Wiki, TripSit); no source states these Sublingual figures

    Onset, Duration & After-effects dose.wiki TripSit

    ROA Onset Peak Offset After Effects Total
    Oral 10-25 min 1-2 hrs 1.5-3 hrs 4-16 hrs 2-5 hrs
    Sublingual 10-25 min 1-2 hrs 1.5-3 hrs 4-16 hrs 2-5 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 5.7
    Strong 6/10

    Strong anxiolysis with strong cognitive impairment, moderate euphoria, mild sedation

    Anxiolysis ×3
    8
    anxiety suppression anxiolytic muscle relaxation
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    10
    motor control loss cognitive impairment memory suppression amnesia double vision
    Euphoria / Mood Lift ×1
    6
    physical euphoria disinhibition
    View methodology →

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Cross-Tolerances

    Other benzodiazepines
    Non-benzodiazepine Z-drugs
    Barbiturates
    Other GABA-A positive modulators

    Effects dose.wiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check Adinazolam with another substance

    Adinazolam's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    💊 Pill Identifier 📖 dose.wiki 📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Adinazolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Adinazolam (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Adinazolam
    Unit
    mg
    Description 
    Adinazolam
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 5-15 · common 15-30 · strong 30-50 · heavy 50+
Sublingual dose (mg): threshold <3 · light 5-15 · common 15-30 · strong 30-50 · heavy 50+

Oral duration: onset 10-25m · peak 1-2h · offset 1.5-3h · total 2-5h · after-effects 4-16h
Sublingual duration: onset 10-25m · peak 1-2h · offset 1.5-3h · total 2-5h · after-effects 4-16h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 22.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.