Me: 63kg white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic; for instance, I loathe cannabis and MDMA makes me feel sad and antisocial. So take this report with a grain of salt-your mileage may vary.
6-APDB
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 30 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 30 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Research-chemical
Aliases: Ema-3, 4-desoxy-mda
Summary
6-APDB (also known as 6-(2-aminopropyl)-2,3-dihydrobenzofuran or 4-Desoxy-MDA) is a stimulant and entactogenic research chemical of the phenethylamine and benzofuran classes. It is a closely related synthetic analogue of MDA and 6-APB and broadly shares the characteristics of serotonin-selective triple monoamine releasers and reuptake inhibitors associated with other entactogenic or empathogenic compounds. 6-APDB was first synthesized and studied along with 5-APDB in 1993 by David E.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-70mg | 70-100mg | 100-130mg | 130mg+ |
Light
Common
Strong
Heavy
Sources
Oral
Dose ladder — PsychonautWikiOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 30-60 min | 2-3 hrs | 2-3 hrs | 7-9 hrs |
Effect Profile
1 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
6.1
Strong
6/10
Strong visuals and auditory effects with mild body load, low headspace
Visual Intensity
×3
10
colour enhancement
autonomous entities
tracers
pattern recognition enhancement
after images
acuity enhancement
Headspace Depth
×3
1
time distortion
Auditory Effects
×1
10
auditory enhancement
auditory distortion
auditory hallucination
Body Load / Somatic Effects
×1
4
teeth grinding
increased heart rate
sweating
Empathogen
8.7
Intense+
9/10
Strong euphoria, sensory enhancement, and empathy with moderate stimulation
Empathy / Social Openness
×3
8
empathy, love, and sociability enhancement
empathy, affection and sociability enhancement
increased sociability
Euphoria / Mood Elevation
×2
10
physical euphoria
cognitive euphoria
euphoria
mood lift
Stimulation
×1
7
stimulation
wakefulness
teeth grinding
increased heart rate
Sensory Enhancement
×1
10
tactile enhancement
colour enhancement
acuity enhancement
increased libido
Stimulant
7.0
Strong+
7/10
Strong euphoria with strong anxiety/jitters, moderate stimulation and focus
Stimulation / Energy
×3
7
stimulation
stamina enhancement
wakefulness
Euphoria / Mood Lift
×2
10
physical euphoria
cognitive euphoria
euphoria
mood lift
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
9
anxiety
increased heart rate
teeth grinding
sweating
Based on reports from:
Tolerance
No tolerance chart. No study has measured how long tolerance to it lasts, so this page shows what is known instead of a curve.
No study has measured tolerance to 6-APDB in people. PsychonautWiki estimates that tolerance halves in 21-30 days and is gone in 2-3 months, without citing a source.
Sources: PsychonautWiki: 6-APDB
Effects
Effect glossary — · full glossary
Positive
Negative
- Stimulation and sedation
Positive
Negative
Positive
Negative
- Visual and audiotory hallucinations itchiness
Combinations
Cross-Check 6-APDB with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 2 reports 1 positive 1 neutral visit
First some notes on a prior experiences and then some notes on a particular experience, si? A chemist friend graciously tested the material by NMR and ESI-MS and found it to be an inorganic salt of 6-APDB. Prior experiences at 80 mg yielded clear ++ experiences without a strong independent character.
Bluelight 2 threads 1 positive 1 neutral visit
Me: 63kg white male. 30 years old. Generally, my reactions to psychoactives are idiosyncratic; for instance, I loathe cannabis and MDMA makes me feel sad and antisocial. So take this report with a grain of salt--your mileage may vary.
The powder I have is off-white/light-tan. I started this thread, posting my marquis, mecke, mandelin, simon`s and robadope tests to try to sort it out and see if someone had anything similar (thanks everyone for helping me out!), however the results were still not very clear.
Bluelight Reference Guide
The Main 6-APDB Thread
hi there, it seems like 6-APDB is available now and will become even more widely available in the near future. i'll receive a sample of this compound soon and i'm wondering if anyone has already sampled it and how it compares to 6-ABP.
Read full thread on Bluelight →
6-APDB's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes 6-APDB, but its built-in data can be thinner than ours. Importing this file adds a separate "6-APDB (Substance Search)" custom substance with our dose ranges and durations, so you can log against whichever you prefer. It leaves tolerance out on purpose, for the reason given under Tolerance above.
⬇ Download import file
Import this file as custom substances
and you get "6-APDB (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer.
Ranges are harm-reduction guidance, not a prescription.
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 6-APDB? Let us know. Reports are reviewed by moderators — this is not posted publicly.