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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-MeO-MiPT Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 27 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Moxy, 5meomipt, 5meo-mipt

    Summary dose.wiki Erowid TripSit PsychonautWiki

    5-Methoxy-N-methyl-N-isopropyltryptamine (also known as 5-MeO-MiPT and moxy) is a lesser-known psychedelic substance of the tryptamine class. 5-MeO-MiPT is chemically related to tryptamines like 5-MeO-DMT and 5-MeO-DiPT. It produces its psychoactive effects through activity at serotonin receptors in the brain.

    Perspectives

    “They do not follow the patterns or harmonies of traditional psychedelic visual effects- rather they are vague, disconnected, and extremely abstract. The headspace is unlike anything else, it’s a blank neutrality and a sense of suppression of the normal channels of psychedelic thought.”

    “In 15 minutes I was already off of baseline, and by an hour it is unquestionably real. There is no visualization to music, but a general turned-on randiness. Dropping at an hour and a half, and out by three hours. Modest but real.”

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Oral 2-5mg 5-10mg 10-15mg 15mg+
    Sublingual 3-7mg 7-15mg 15-20mg 20mg+
    Smoked 5-10mg 10-15mg 15-20mg 20mg+
    Light Common Strong Heavy
    Sources· 1 of 3 ladders not fully identified

    Oral

    Dose ladder — dose.wiki

    Sublingual

    Dose ladder — Light, Common: not identified · Strong, Heavy: same as the Smoked row (dose.wiki, Drugs.Wiki, PsychonautWiki)

    Smoked

    Dose ladder — dose.wiki, PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-40 min 30-60 min 2-3 hrs 2-3 hrs 2-4 hrs 5-8 hrs
    Sublingual 19-60 min 30-60 min 1-2 hrs 1-2 hrs 1-3 hrs 3-7 hrs
    Smoked <1-2 min 1-4 min 15-30 min 1-2 hrs 1-2 hrs 5-8 hrs

    Effect Profile

    88 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 60 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, and auditory effects with strong body load

    Visual Intensity ×3
    10
    internal hallucinations colour enhancement autonomous entities drifting tracers colour shifting +6 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression time distortion +1 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction muscle tension bodily pressures increased heart rate
    Empathogen 9.7
    Extreme 10/10

    Strong empathy, stimulation, sensory enhancement, and euphoria

    Empathy / Social Openness ×3
    10
    empathy enhancement empathy empathy, love, and sociability enhancement empathy, affection and sociability enhancement
    Euphoria / Mood Elevation ×2
    9
    euphoria emotion enhancement
    Stimulation ×1
    10
    stimulation wakefulness restlessness increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement enhanced tactile sensation spontaneous tactile sensations colour enhancement acuity enhancement visual acuity enhancement +1 more

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Based on Erowid’s basics page indicating a short tolerance window with near‑baseline by 5–7+ days; quantitative values are heuristic for planning gaps, not pharmacokinetic measurements. Cross‑tolerance pattern inferred from general psychedelic class behavior (TripSit).

    Cross-Tolerances

    LSD/psilocybin/other serotonergic psychedelics

    Effects Erowid Bluelight

    Aggregated from 60 single-substance Erowid and 28 Bluelight experience reports; 45 Erowid reports where another drug was taken too are left out

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Positive Effects 63

    52.3% (95% interval 42 to 62 percent) 84%
    52.3% (95% interval 42 to 62 percent) 82%
    47.7% (95% interval 38 to 58 percent) 88%
    43.2% (95% interval 33 to 54 percent) 88%
    35.3% (95% interval 26 to 46 percent) 80%
    35.2% (95% interval 26 to 46 percent) 85%
    32.1% (95% interval 18 to 51 percent) 84%
    30.7% (95% interval 22 to 41 percent) 90%
    29.5% (95% interval 21 to 40 percent) 86%
    28.6% (95% interval 15 to 47 percent) 86%
    28.6% (95% interval 15 to 47 percent) 84%
    28.6% (95% interval 15 to 47 percent) 81%
    Auditory Effects 27.3% (95% interval 19 to 37 percent) 81%
    25.0% (95% interval 17 to 35 percent) 86%
    25.0% (95% interval 13 to 43 percent) 82%
    21.4% (95% interval 10 to 40 percent) 85%
    21.4% (95% interval 10 to 40 percent) 85%
    21.4% (95% interval 10 to 40 percent) 86%
    21.4% (95% interval 10 to 40 percent) 78%
    20.5% (95% interval 13 to 30 percent) 80%
    Show 43 more positive effects
    20.4% (95% interval 13 to 30 percent) 87%
    18.3% (95% interval 11 to 30 percent) –
    17.9% (95% interval 8 to 36 percent) 80%
    17.9% (95% interval 8 to 36 percent) 78%
    17.9% (95% interval 8 to 36 percent) 81%
    15.9% (95% interval 10 to 25 percent) 85%
    14.3% (95% interval 6 to 32 percent) 78%
    14.3% (95% interval 6 to 32 percent) 85%
    10.7% (95% interval 4 to 27 percent) 83%
    10.7% (95% interval 4 to 27 percent) 87%
    10.7% (95% interval 4 to 27 percent) 82%
    10.7% (95% interval 4 to 27 percent) 80%
    7.1% (95% interval 2 to 23 percent) 78%
    7.1% (95% interval 2 to 23 percent) 82%
    7.1% (95% interval 2 to 23 percent) 80%
    7.1% (95% interval 2 to 23 percent) 85%
    7.1% (95% interval 2 to 23 percent) 88%
    7.1% (95% interval 2 to 23 percent) 82%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 90%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 75%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 70%
    3.6% (95% interval 1 to 18 percent) 90%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 95%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 65%

    Adverse Effects 43

    38.6% (95% interval 29 to 49 percent) 79%
    35.7% (95% interval 21 to 54 percent) 82%
    27.3% (95% interval 19 to 37 percent) 84%
    21.6% (95% interval 14 to 31 percent) 80%
    17.9% (95% interval 8 to 36 percent) 83%
    17.0% (95% interval 11 to 26 percent) 80%
    14.3% (95% interval 6 to 32 percent) 79%
    14.3% (95% interval 6 to 32 percent) 79%
    11.7% (95% interval 6 to 22 percent) –
    10.7% (95% interval 4 to 27 percent) 77%
    10.7% (95% interval 4 to 27 percent) 82%
    10.7% (95% interval 4 to 27 percent) 80%
    7.1% (95% interval 2 to 23 percent) 78%
    7.1% (95% interval 2 to 23 percent) 65%
    7.1% (95% interval 2 to 23 percent) 80%
    7.1% (95% interval 2 to 23 percent) 80%
    7.1% (95% interval 2 to 23 percent) 88%
    7.1% (95% interval 2 to 23 percent) 75%
    7.1% (95% interval 2 to 23 percent) 90%
    7.1% (95% interval 2 to 23 percent) 78%
    Show 23 more adverse effects
    6.8% (95% interval 3 to 14 percent) 80%
    5.7% (95% interval 2 to 13 percent) 75%
    5.0% (95% interval 2 to 14 percent) –
    3.6% (95% interval 1 to 18 percent) 70%
    3.6% (95% interval 1 to 18 percent) 70%
    3.6% (95% interval 1 to 18 percent) 65%
    3.6% (95% interval 1 to 18 percent) 75%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 75%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 75%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 70%
    3.6% (95% interval 1 to 18 percent) 90%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 95%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 75%
    3.6% (95% interval 1 to 18 percent) 80%
    3.6% (95% interval 1 to 18 percent) 85%
    3.6% (95% interval 1 to 18 percent) 85%

    Also reported in combinations. In the 45 5-MeO-MiPT reports where another drug was taken too, 3 (6.7%) mention hospital, emergency services or an overdose, 1 (2.2%) a seizure and 1 (2.2%) psychosis. In the 60 single-substance reports: 15.0%, 1.7% and 1.7%. These are not in the figures above: they cannot be put down to 5-MeO-MiPT alone, and a mention is not always something that happened to the writer.

    Combinations TripSit

    Cross-Check 5-MeO-MiPT with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 5 positive 3 cautionary visit
    2 Amazing Life Changing Trips positive exp #107991

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    Reeushima · 5-MeO-MIPT · vaporized / repeated smoked / repeated smoked
    Mellow Moxy positive exp #70897

    I've decide to share my first experience with 5-MeO-MiPT, it was an enjoyable one! I have a fairly decent amount of experience with psychedelics, having tried the following, most more than once: Weed, Hashish, Magic Mushrooms, DXM, MDMA, PMA, Meth, Codeine, Salvia Divinorum, AMT, 5-MeO-DiPT, Ketamine, 2C-E, 4-AcO-DMT,...

    Schwag · 10 mg oral / 1 repeated smoked / 1 bowl smoked
    Party Changing positive exp #73230

    I wanted to start out writing this as describing who I am but you are not me and I am not you...I am I. I and I share a universal conscious that exists based on fear and love. I am accepted by nature and Love and distracted by man and Fear.

    Y · 25 mg insufflated
    Break on Through positive exp #113349

    [This trip report is written from a multiple-identity perspective.] The following Greek letters have been changed to protect the innocent. This trip report is written by Omicron, with contributions by Zeta, Delta, Kappa, Lambda, Psi, and Rho. This was our third experience with taking 5-MeO-MiPT.

    Kaleida · 2000 mg oral / 10 mg oral / repeated smoked
    Dark Carnival at the End of Time positive exp #110775

    0:00/6:30PM: I just get off my shift volunteering for the burn and a friend of mine offers me a capsule. We were planning to take LSD and he tells me Moxy is the perfect thing to prime me for an acid trip. As he described Moxy it is supposed to feel like LSD mixed with MDMA.

    ChromaticSloth · 5-MeO-MIPT · 8 mg oral
    Death and Rebirth cautionary exp #29734

    Shulgin states that the oral dose for this drug is 4-6 mg. As I do with any drug that I haven't tried before, I weighed out a series of dosages on a precision scale, ranging from somewhat less than the recommended dose (3 mg) to approximately twice recommended dose (12 mg).

    K · 5-MeO-MIPT · 25 mg oral
    Energy Realignment and the Joy of Life cautionary exp #58528

    Life for the past month or so has been dull. I have had an ever-present sensation in the pit of my stomach of depression and anxiety which has been very difficult to shake and pretty much impossible to get rid of.

    Xorkoth · 6.0 mg oral / 1 repeated inhaled
    A Challenging Night cautionary exp #94134

    Before getting into this Article IΒ’d like to tell you about my history with psychoactive substances. I smoke cannabis on an almost daily basis for about 10 years now. Before that I regularly abused butane gas at very low age. I guess I was about 11 years old when this happened.

    Shoryuken · 5-MeO-MIPT · 8 mg sublingual / 5 mg sublingual / 4 mg oral / 10 mg sublingual
    Dose.wiki 1 report 1 neutral visit
    The Stillness and the Fluttering 20 mg oral in gel cap neutral

    This would be my first foray into the 5-MeO-Tryptamines and I would later come to understand them as their own class of drug entirely. They are incomparable to other psychedelics for several reasons- The first is a lack of sensory stimulation and distortions…

    by nervewing

    Bluelight Reference Guide Bluelight

    Tryptamines The Big & Dandy 5-MeO-MiPT Thread - Part 2

    The Big and Dandy 5-MeO-MiPT Thread (part 2) External Information Links Erowid 5-MeO-MiPT Vault Wikipedia 5-MeO-MiPT Entry TIHKAL 5-MeO-MiPT Entry Focused Discussion Sub-threads 5-MeO-MiPT + MDMA Combination Thread Previous Threads The Big & Dandy 5-MeO-MiPT Thread - Part 1

    Read full thread on Bluelight β†’

    PiHKAL / TiHKAL Shulgin

    TiHKAL #40: 5-MeO-MIPT

    “In 15 minutes I was already off of baseline, and by an hour it is unquestionably real. There is no visualization to music, but a general turned-on randiness. Dropping at an hour and a half, and out by three hours. Modest but real.”

    β€” Alexander Shulgin, TiHKAL (with 1.5 mg, orally)
    →

    Helpful Links

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 5-MeO-MiPT, but its built-in entry only covers Oral, Smoked. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "5-MeO-MiPT (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Custom Unit doses
    • Sublingualcommon ~ 11 mg
    Dose & duration (reference)
    5-MeO-MiPT: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    Sublingual dose (mg): threshold 0.5-1 Β· light 3-7 Β· common 7-15 Β· strong 15-20 Β· heavy 20+
    
    Sublingual duration: onset 0.32-1h Β· come-up 0.5-1h Β· peak 1-2h Β· offset 1-2h Β· total 3-7h Β· after-effects 1-3h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.