3,4-CFPP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 3,4-cfp, 3cl-4f-p, Kleferein, 3-chloro-4-fluoro-piperein
Summary
Very little pharmacological or toxicological data exists. Based on structural similarity to mCPP and TFMPP, this compound likely acts as a non-selective serotonin receptor agonist and serotonin releaser. These phenylpiperazines are notorious for producing nausea, migraines, anxiety, and dysphoria rather than euphoria.
Dose Information
Dose basis. Oral: Ranges are compiled from scattered user reports and by analogy to related phenylpiperazines; no formal human data exist. Always allergy test (โ1โ2 mg) and use a calibrated milligram scale. Expect more nausea and headache than with classical empathogens; redosing tends to increase adverse effects disproportionately. Evidence quality: anecdotal. Insufflated: Phenylpiperazines can be irritating to mucosa and more likely to cause headaches and nausea when snorted; TFMPP/pFPP reports specifically note sore throat/nasal irritation. Prefer oral route for lower adverse-event rates. Evidence: user reports on piperazines; no CFPP-specific data. Evidence quality: anecdotal. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-50mg | 50-100mg | 100-150mg | 150mg+ |
| Insufflated | 5-15mg | 15-40mg | 40-70mg | 70mg+ |
Sources
Oral
Dose ladder — Drugs.WikiInsufflated
Dose ladder — Drugs.WikiOnset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-60 min | 1-3 hrs | 1-2 hrs | 2.33-6 hrs |
| Insufflated | 5-15 min | 1-3 hrs | 1-2 hrs | 2.08-5.25 hrs |
Effect Profile
Scores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation with mild euphoria, low empathy and sensory enhancement
Mild stimulation and euphoria with strong anxiety/jitters
Tolerance
Tolerance Decay
Effects
Effect glossary — · full glossary
Combinations
Cross-Check 3,4-CFPP with another substanceHelpful Links
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The PsychonautWiki Journal logging app doesn't include every substance. To track 3,4-CFPP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
3,4-CFPP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 20 ยท light 20-50 ยท common 50-100 ยท strong 100-150 ยท heavy 150+ Insufflated dose (mg): threshold 5 ยท light 5-15 ยท common 15-40 ยท strong 40-70 ยท heavy 70+ Oral duration: onset 0.33-1h ยท peak 1-3h ยท offset 1-2h ยท total 2.33-6h ยท after-effects 1-6h Insufflated duration: onset 5-15m ยท peak 1-3h ยท offset 1-2h ยท total 2.08-5.25h ยท after-effects 1-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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