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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-MAR Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Summary dose.wiki

    3-MAR produces a clear, focused stimulation reminiscent of 4-MAR but with more pronounced head pressure and emotional lability. Users describe strong synergy with amphetamine yet diminishing returns when redosed in isolation. Nasal administration is sharply caustic; vaporizing the freebase yields a rapid rush but encourages compulsive re-administration.

    Dose Information Drugs.Wiki

    Dose basis. Ranges are compiled from scattered user reports and analog extrapolation (not clinical data). Potency may vary by isomer ratio (cis/trans) and salt vs freebase. Start low, titrate cautiously, and avoid rapid redosing. User reports describe notable causticity and mucosal irritation with aminorex analogues; dilute finely, avoid repeated back‑to‑back lines, and rinse gently with isotonic saline post‑use. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-20mg 20-35mg 35mg+
    Insufflated 3-7mg 7-15mg 15-25mg 25mg+
    Smoked 2-5mg 5-10mg 10-20mg 20mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — Drugs.Wiki

    Insufflated

    Dose ladder — Drugs.Wiki

    Smoked

    Dose ladder — Drugs.Wiki

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 20-40 min 0.5-3 hrs 2-6 hrs 4-24 hrs 2.83-9.67 hrs
    Insufflated 5-10 min 0.5-3 hrs 2-6 hrs 4-24 hrs 2.58-9.17 hrs
    Smoked <1-2 min 0.5-3 hrs 2-6 hrs 4-24 hrs 4-12 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.1
    Moderate+ 5/10

    Strong anxiety/jitters with moderate stimulation, mild euphoria and focus

    Stimulation / Energy ×3
    7
    stimulation increased energy wakefulness
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    5
    focus enhancement motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate bruxism vasoconstriction

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~21d

    Anecdotal: tolerance rises rapidly during a binge and partially recovers after 3–5 days; baseline by 7–14 days if no further use. Cross‑tolerance with other aminorex derivatives and common stimulants is likely but unquantified.

    Effects dose.wiki

    Positive
    Negative
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check 3-MAR with another substance

    →

    Helpful Links

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 3-MAR there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "3-MAR (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    3-MAR
    Unit
    mg
    Description
    3-MAR
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 5 Β· light 5-10 Β· common 10-20 Β· strong 20-35 Β· heavy 35+
    Insufflated dose (mg): threshold 3 Β· light 3-7 Β· common 7-15 Β· strong 15-25 Β· heavy 25+
    Smoked dose (mg): threshold 1-2 Β· light 2-5 Β· common 5-10 Β· strong 10-20 Β· heavy 20+
    
    Oral duration: onset 20-40m Β· peak 0.5-3h Β· offset 2-6h Β· total 2.83-9.67h Β· after-effects 4-24h
    Insufflated duration: onset 5-10m Β· peak 0.5-3h Β· offset 2-6h Β· total 2.58-9.17h Β· after-effects 4-24h
    Smoked duration: onset <1-2m Β· peak 0.5-3h Β· offset 2-6h Β· total 4-12h Β· after-effects 4-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 15 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.