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    Disclaimer
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25T-4-NBOMe Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • 29 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: 25t4-nbome

    Psychedelic Research-chemical

    Summary TripSit

    A psychedelic RC of the NBOMe class of drugs that is expected to cause hallucinations. Limited human use has been recorded on this drug and caution should be used with dosing.

    Dose Information dose.wiki TripSit

    ROA Light Common Strong Heavy
    Sublingual 150-300ug 300-750ug 750-1200ug 1200ug+
    Light Common Strong Heavy
    Sources

    Sublingual

    Dose ladder — dose.wiki, TripSit

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Sublingual 20-45 min 5-9 hrs 2-12 hrs 5-9 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 4.2
    Moderate 4/10

    Moderate visuals with moderate body load, mild headspace

    Visual Intensity ×3
    6
    color enhancement drifting visual distortions brightened colour
    Headspace Depth ×3
    4
    introspection time distortion confusion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    6
    nausea vasoconstriction increased heart rate
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations TripSit

    Cross-Check 25T-4-NBOMe with another substance

    25T-4-NBOMe's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 25T-4-NBOMe there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "25T-4-NBOMe (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    25T-4-NBOMe
    Unit
    µg
    Description 
    25T-4-NBOMe
Source: SubstanceSearch (substancesearch.com)

Sublingual dose (µg): light 150-300ug · common 300-750ug · strong 750-1200ug · heavy 1200ug+

Sublingual duration: onset 20-45m · peak 5-9h · total 5-9h · after-effects 2-12h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 525 µg (Sublingual).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.