Prior drug experience - Cannabis, Alcohol, aMT, 2C-i, LSD, psilocybin, cocaine, salvia, amphetamine, MDMA, MDA I wrote this trip report in my notes in my iPhone through the entire trip, this is real-time reports. Duration: 8hrs 3pm - 9pm - 8-10 vape bags and 4 joints of chocolate cheesecake.
25I-NBOH
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 29 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Cimbi-27, Nboh-2c-i, nboh-2ci
Summary
25I-NBOH (Cimbi-27, also known as NBOH-2C-I) is a psychedelic phenethylamine and research chemical, belonging to the hallucinogen class. It is approximately 2-3 times less potent than 25I-NBOMe but significantly more potent than 2C-I. It is not orally active and must be administered sublingually or buccally. Extreme vasoconstriction and cardiovascular strain have been reported at higher doses.
Perspectives
“I can't really see any permanent psychedelic therapy uses for this one, as while it does fill the user with beautiful colorful empathy while it lasts, it eventually fades to the exact same state as before. Afterglow as negligible. That might just be me though. I can say though, it had the most beautiful and intense visuals of any trip.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 200-500µg | 500-900µg | 900-1400µg | 1400µg+ |
| Buccal | 200-500µg | 500-900µg | 900-1400µg | 1400µg+ |
Light
Common
Strong
Heavy
Sources
Sublingual
Dose ladder — Light: PsychonautWiki · Common: dose.wiki, PsychonautWiki · Strong: dose.wiki, Drugs.Wiki, PsychonautWiki · Heavy: dose.wiki, Drugs.WikiBuccal
Dose ladder — Light: same as the Sublingual row (PsychonautWiki) · Common: same as the Sublingual row (dose.wiki, PsychonautWiki) · Strong: same as the Sublingual row (dose.wiki, Drugs.Wiki, PsychonautWiki) · Heavy: same as the Sublingual row (dose.wiki, Drugs.Wiki); no source states these Buccal figuresOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Sublingual | 15-60 min | 30-90 min | 2-3.5 hrs | 1.5-2.5 hrs | 5-10 hrs |
| Buccal | 15-60 min | 30-90 min | 2-3.5 hrs | 1.5-2.5 hrs | 5-10 hrs |
Effect Profile
4 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
8.4
Intense
8/10
Strong visuals, auditory effects, and headspace with strong body load
Visual Intensity
×3
10
colour enhancement
drifting
tracers
synaesthesia
pattern recognition enhancement
scenery slicing
+6 more
Headspace Depth
×3
9
conceptual thinking
recursion
emotion enhancement
personal bias suppression
time distortion
confusion
Auditory Effects
×1
10
auditory distortion
auditory hallucination
synaesthesia
Body Load / Somatic Effects
×1
10
nausea
temperature regulation suppression
vasoconstriction
muscle tension
increased heart rate
Stimulant
4.4
Moderate
4/10
Moderate euphoria with strong anxiety/jitters, mild stimulation and focus
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
6
physical euphoria
euphoria
Focus / Productivity
×2
4
analysis enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
restlessness
paranoia
increased heart rate
vasoconstriction
muscle tension
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Half tolerance
7d
Baseline
~14d
Rapid within-session tolerance typical of serotonergic psychedelics; redosing adds side effects with limited benefit. Return to baseline generally reported within 1–3 weeks.
Cross-Tolerances
Classical psychedelics (e.g., LSD, psilocybin)
NBOMe series
DOx series (e.g., DOC)
Effects
Aggregated from 4 single-substance Erowid experience reports; 8 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 4 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 2
3 of 4
–
3 of 4
–
Adverse Effects 0
Also reported in combinations. In the 8 25I-NBOH reports where another drug was taken too, 2 mention hospital, emergency services or an overdose, 0 a seizure and 0 psychosis (too few reports for percentages). In the 4 single-substance reports: 0, 0 and 0. These are not in the figures above: they cannot be put down to 25I-NBOH alone, and a mention is not always something that happened to the writer.
Combinations
Cross-Check 25I-NBOH with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 7 reports 4 positive 3 neutral visit
In the summer of 2014, the guy I was dating at the time managed to acquire a (in my opinion) ridiculous amount of NBOH 25i. During this time, I bore witness to a whole range of different reactions from friends and anyone he would sell to, as well as experimenting heavily myself.
Background: I have little experience with psychedelics. Took shrooms/truffles 6 times since july 2015. And once LSD about 2 weeks ago. A few experiences with 2cb and one with 2cp sum this all up. So I know my deal with phens and tryptamines.
Dose: 250ug 25i-NBOH, sublingual Setting: Alone in my room, calm. Slow to come on, about 1 hour of anticipation. T+1 A certain dizziness/vertigo emerges. Vision is blurred. I feel sleepy. T+1:30 Altered edge perception and some colour enhancement. Definite shimmering. Potential visuals in the periphery.
Wonderful First Experience This is my first trip report, so I apologize for the possible lack of depth. I am 22 years old, I have a very large background in psychedelic drug usage among many other substances. I obtained the 25I-NBOH through a trusted vendor earlier in the week.
25I-NBOH Test Trial 1 The first entry is written verbatim as I experienced the drug. The second is a timeline describing the effects. 2 grams of B+ strain Psilocybin mushrooms were consumed 24 hrs before. This shouldn't affect the trip, because psilo is metabolized rather quickly from my understanding.
Essentially I made a 25I-NBOH solution which should have turned out to be 1mg per ml, 22ml in total. I attempted the method you just squirt the known amount in your mouth and for me this would have been 1mg then leave it there for awhile and be done with it.
Dose.wiki 1 report 1 positive visit
I can't really see any permanent psychedelic therapy uses for this one, as while it does fill the user with beautiful colorful empathy while it lasts, it eventually fades to the exact same state as before. Afterglow as negligible. That might just be me…
Bluelight Reference Guide
Phenethylamines The Big and Dandy 25x-NBOH Megathread | Post your 25x-NBOH info and questions here.
I thought it would be nice to have a spot where all of the various 25x-NBOH series can be discussed as a group or individually, questions can be answered, and information can be dispersed. Relate your usage and discuss!
Read full thread on Bluelight →
25I-NBOH's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has 25I-NBOH, but its built-in entry only covers Sublingual. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "25I-NBOH (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Custom Unit doses
- Buccalcommon ~ 700 µg
Dose & duration (reference)
25I-NBOH: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Buccal dose (µg): threshold 50-100ug · light 200-500 · common 500-900 · strong 900-1400 · heavy 1400+ Buccal duration: onset 0.25-1h · come-up 0.5-1.5h · peak 2-3.5h · offset 1.5-2.5h · total 5-10h · after-effects 3-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
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