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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2-MMC Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 29 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: Ortho, 2-methyl mc, Orthophedrone, Orthomephedrone, 2mmc, ortomephedrone, 2-methylmethcathinone, 2methylmethcathinone, 2-mephedrone

    Stimulant Research-chemical

    Summary dose.wiki TripSit PsychonautWiki

    2-MMC (2-Methylmethcathinone, also known as Ortho-Mephedrone) is a synthetic stimulant of the cathinone class. It acts as a serotonin-norepinephrine-dopamine releasing agent with higher affinity for DAT and NET than SERT, producing more focused, amphetamine-like stimulation with less euphoria than its isomers 3-MMC and 4-MMC.

    Dose Information source varies by route

    ROA Light Common Strong Heavy
    Oral 20-50mg 50-100mg 100-135mg 135mg+
    Insufflated 5-15mg 15-40mg 40-80mg 80mg+
    Intravenous 1-10mg 10-30mg 30-50mg 50mg+
    Light Common Strong Heavy
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Insufflated

    Dose ladder — dose.wiki, TripSit

    Intravenous

    Dose ladder — PsychonautWiki

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-45 min 30-60 min 1-2 hrs 1-2 hrs 2-8 hrs 2.83-5.75 hrs
    Insufflated 1-5 min 5-15 min 1-2 hrs 1-2 hrs 2-8 hrs 2.1-4.33 hrs
    Rectal 10-20 min 20-40 min 1-2 hrs 1-2 hrs 2-8 hrs 2.5-5 hrs
    Intravenous 1-10 sec 5-10 min 15-30 min 30-45 min - 1-3 hrs

    Effect Profile

    4 reports

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 4.7
    Moderate+ 5/10

    Strong sensory enhancement with moderate stimulation, mild euphoria, low empathy

    Empathy / Social Openness ×3
    3
    empathy & sociability
    Euphoria / Mood Elevation ×2
    5
    euphoria mood lift
    Stimulation ×1
    6
    stimulation increased energy increased heart rate
    Sensory Enhancement ×1
    8
    music appreciation enhancement tactile enhancement increased libido
    Stimulant 5.5
    Strong 6/10

    Moderate euphoria and focus with moderate anxiety/jitters, mild stimulation

    Stimulation / Energy ×3
    5
    stimulation increased energy
    Euphoria / Mood Lift ×2
    7
    euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    6
    cognitive enhancement analysis enhancement motivation enhancement
    ⚠ Anxiety / Jitters ×1
    7
    anxiety increased heart rate sweating
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 2-MMC
    View methodology →

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects Erowid

    Aggregated from 4 single-substance Erowid experience reports

    Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

    Too few reports for bars: these effects come from 4 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 3

    3 of 4 –
    3 of 4 –
    3 of 4 –

    Adverse Effects 0

    Combinations

    Cross-Check 2-MMC with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 4 reports 1 positive 2 neutral 1 cautionary visit
    Lost in Time and Thought neutral exp #118648

    At the time I'm writing this, I still feel a bit odd and dissociated from the real world, so I apologize if I make any mistakes in my grammatic. It was morning, 7th of January, and I just called in sick from work because, well, simply I did not really feel like it today, my package that I ordered, 6 grams of 2-Methylme...

    Anonymous · 2-Methylmethcathinone · repeated insufflated
    My Body Had Enough - Delirium & Panic Attack cautionary exp #118542

    I ordered 2 grams of 2-MMC crystals from some Dutch site to just have some fun with my friends for the weekend, it took like 4 days to come, and I am very excited for this shit, decided to write a report since I didn't find much information about it and thought it would be helpful for people that are interested in tryi...

    rtorigo · 2-Methylmethcathinone · 70 mg insufflated / smoked / smoked / 20 mg insufflated
    What Adderall Aspires to Be positive exp #109240

    First and foremost, this stuff up the nose hurts like a motherfucker. If 4-FA is a 10/10 on the pain scale (which it is) then I'd put 2-MMC around an 8-8.5/10. That said the burn subsides within a minute or two. The drip is surprisingly not terrible, kinda taste like adderall but not quite as sweet.

    Zirtonic · 2-Methylmethcathinone · 75 mg insufflated / 75 mg insufflated / 25 mg vaporized
    Decided Not to Take Anymore Today neutral exp #116043

    Function Variant of 3-MMC I received my package of 2-MMC today and decided to write this report as there is hardly any info about this substance online. The recent Dutch ban of 3-MMC has resulted in RC vendors marketing 2-MMC as an alternative.

    BXL1000 · 2-Methylmethcathinone · 125 mg oral / 100 mg oral / 75 mg insufflated / oral
    2-MMC's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 2-MMC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "2-MMC (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    2-MMC
    Unit
    mg
    Description 
    2-MMC
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 20-50 · common 50-100 · strong 100-135 · heavy 135+
Insufflated dose (mg): light 5-15 · common 15-40 · strong 40-80 · heavy 80+
Intravenous dose (mg): threshold 1 · light 1-10 · common 10-30 · strong 30-50 · heavy 50+

Oral duration: onset 20-45m · come-up 0.5-1h · peak 1-2h · offset 1-2h · total 2.83-5.75h · after-effects 2-8h
Insufflated duration: onset 1-5m · come-up 5-15m · peak 1-2h · offset 1-2h · total 2.1-4.33h · after-effects 2-8h
Rectal duration: onset 10-20m · come-up 20-40m · peak 1-2h · offset 1-2h · total 2.5-5h · after-effects 2-8h
Intravenous duration: onset 1-10s · come-up 5-10m · peak 15-30m · offset 30-45m · total 1-3h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.