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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2-FEA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 30 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: O-fluoroethamphetamine, 2-fluoroethylamphetamine, Ortho-fluoroethamphetamine

    Psychedelic Stimulant Research-chemical

    Summary dose.wiki TripSit PsychonautWiki

    2-Fluoroethamphetamine (2-FEA) is a novel stimulant substance of the amphetamine class that produces classical stimulant effects such as stimulation, enhanced focus and euphoria when administered. The exact effects of 2-FEA are not well known by its users with anecdotal reports suggesting only minimal activity and possible serotonergic qualities. 2-FEA is sold on the online research chemical market.

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Insufflated 20-30mg 30-40mg 40-60mg 60mg+
    Light Common Strong Heavy
    Sources

    Insufflated

    Dose ladder — dose.wiki, PsychonautWiki

    Onset, Duration & After-effects dose.wiki PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-60 min 30-45 min 1.5-3 hrs 1-2 hrs 2-6 hrs 3.33-6.75 hrs
    Insufflated 5-15 min 15-30 min 1.5-3 hrs 1-2 hrs 2-6 hrs 2.83-5.75 hrs
    Rectal 5-20 min 20-40 min 1.5-3 hrs 1-2 hrs 2-6 hrs 2.91-6 hrs
    Sublingual 15-30 min 25-40 min 1.5-3 hrs 1-2 hrs 2-6 hrs 3.17-6.17 hrs

    Effect Profile

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 1.8
    Light 2/10

    Low visuals and headspace with strong body load

    Visual Intensity ×3
    3
    drifting pattern recognition enhancement
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    8
    vasoconstriction nausea teeth grinding increased heart rate
    Empathogen 3.4
    Light+ 3/10

    Moderate stimulation and euphoria with mild sensory enhancement

    Empathy / Social Openness ×3
    0
    Euphoria / Mood Elevation ×2
    6
    physical euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 6.6
    Strong+ 7/10

    Strong focus with strong anxiety/jitters, moderate stimulation and euphoria

    Stimulation / Energy ×3
    7
    stimulation stamina enhancement wakefulness
    Euphoria / Mood Lift ×2
    7
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding vasoconstriction
    Based on reports from:
    PsychonautWiki 2-FEA
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Half tolerance 7d Baseline ~14d

    Anecdotal patterns similar to other amphetamines: short‑term tolerance can develop across consecutive days; spacing use by at least 1–2 weeks is commonly reported to reduce residual insomnia/low mood. Data quality: anecdotal.

    Effects dose.wiki PsychonautWiki

    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check 2-FEA with another substance

    2-FEA's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 dose.wiki 📖 PsychonautWiki
    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has 2-FEA, but its built-in entry only covers Insufflated. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    ⬇ Download import file Import this file as custom substances and you get "2-FEA (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Duration (reference) 
    2-FEA: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)


Oral duration: onset 0.33-1h · come-up 30-45m · peak 1.5-3h · offset 1-2h · total 3.33-6.75h · after-effects 2-6h
Rectal duration: onset 5-20m · come-up 20-40m · peak 1.5-3h · offset 1-2h · total 2.91-6h · after-effects 2-6h
Sublingual duration: onset 15-30m · come-up 25-40m · peak 1.5-3h · offset 1-2h · total 3.17-6.17h · after-effects 2-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Ranges are harm-reduction guidance, not a prescription.