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    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Valerylfentanyl Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • partial dose data
    • 29 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: VF

    Depressant Research-chemical Opioid

    Summary TripSit

    Opioid that is a higher homologue of Butyrfentanyl with greatly reduced potency.

    Dose Information dose.wiki TripSit

    Dose basis. The single "50 mg and above" figure is a community-reported threshold carried from TripSit, not a clinical measurement, and no upper bound has ever been established — the open end is genuine, not a formatting artifact. Valerylfentanyl is a weak partial mu-agonist relative to fentanyl, but material sold under the name is frequently misrepresented or contaminated with far more potent analogues, which is the actual hazard at this dose scale.

    ROA Light
    Oral 50mg+
    Light
    Sources

    Oral

    Dose ladder — dose.wiki, TripSit

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset Falls quickly once you stop, at a rate you can't judge. After any break, treat your tolerance as gone.

    No tolerance chart. Our decay curves for opioids were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    Opioid tolerance drops fast when you stop, and even a few days off can be enough, so a dose that used to be normal can now stop your breathing. Overdose deaths rise sharply after prison, detox or leaving treatment, and tolerance also falls during a hospital stay. After any break, start with a much smaller amount, try a test dose first, don't use alone, and keep naloxone within reach. Alcohol, benzodiazepines, gabapentinoids and other sedatives make an opioid overdose much more likely.

    Sources: FRANK: heroin · National Harm Reduction Coalition · WHO: opioid overdose · Merrall et al. 2010 · Binswanger et al. 2007 · Strang et al. 2003 · FDA 2019: gabapentinoids and breathing

    Combinations TripSit

    Cross-Check Valerylfentanyl with another substance

    Valerylfentanyl's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📖 TripSit
    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Valerylfentanyl there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Valerylfentanyl
    Unit
    mg
    Description 
    Valerylfentanyl
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 50+

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.